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NR283/ NR 283 EXAM 1: (NEW 2025/ 2026
UPDATE) PATHOPHYSIOLOGY REVIEW| QUESTIONS &
ANSWERS| GRADE A| 100% CORRECT (VERIFIED
SOLUTIONS)- CHAMBERLAIN
Bradykinin - ANS ✓activation of plasma proteins, vasodilation and increase
capillary permeability, pain, fever
Complement System - ANS ✓activation of plasma protein cascade, vasodilation
and increased capillary permeability, chemotaxis, increase histamine
Chemotactic factors - ANS ✓mast cell granules, attract neutrophils to site
Antigens - ANS ✓Foreign material that invades the body that stimulates an
immune response
Antibodies - ANS ✓specific proteins produced in humoral response to bind with
an antigen. Produced by B lymphocytes.
I Hypersensitivity - ANS ✓hay fever; anaphalaxis - IgE - mast cells release
histamine - inflammation and pruritis
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II Hypersensitivity - ANS ✓"Ant - Body" IgG and IgM, cytotoxicity, ABO blood
transfusions danger
III Hypersensitivity - ANS ✓Immune Complex Clumps in blood vessel walls,
causes complement cascades and neutrophil degranulation, causes inflammation
and tissue damage. ex: lupus
IV Hypersensitivity - ANS ✓cell mediated, regulated by T-cells, delayed, 24
hours before a response, poison ivy
IgG - ANS ✓most common in blood, creates passive immunity in newborn
IgM - ANS ✓bound to B-lymphocytes, the to increase immune response
IgE - ANS ✓binds to mast cells, causes release of histamine
innate immunity - ANS ✓related to ethnicity, 2 step response system, primary
and secondary. Ex: T-lymphocytes, memory cells, or T-cells.
Passive Immunity - ANS ✓when antibodies are passed from one person to
another
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