, TEXTBOOK of
CLINICAL
ECHOCARDIOGRAPHY
, SIXTH EDITION
TEXTBOOK of
CLINICAL
ECHOCARDIOGRAPHY
Catherine M. Otto, MD
J. Ward Kennedy-Hamilton Endowed Chair in Cardiology
Professor of Medicine
University of Washington School of Medicine;
Director, Heart Valve Disease Clinic;
Associate Director, Echocardiography Laboratory
University of Washington Medical Center
Seattle, Washington
, 1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
TEXTBOOK OF CLINICAL ECHOCARDIOGRAPHY: SIXTH EDITION ISBN: 978-0-323-48048-2
Copyright © 2018 by Elsevier, Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or
mechanical, including photocopying, recording, or any information storage and retrieval system, without
permission in writing from the Publisher. Details on how to seek permission, further information about the
Publisher’s permissions policies, and our arrangements with organizations such as the Copyright Clearance
Center and the Copyright Licensing Agency can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher
(other than as may be noted herein).
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience
broaden our understanding, changes in research methods, professional practices, or medical treatment
may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating
and using any information, methods, compounds, or experiments described herein. In using such
information or methods, they should be mindful of their own safety and the safety of others, including
parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the
most current information provided (i) on procedures featured or (ii) by the manufacturer of each
product to be administered, to verify the recommended dose or formula, the method and duration of
administration, and contraindications. It is the responsibility of practitioners, relying on their own
experience and knowledge of their patients, to make diagnoses, to determine dosages and the best
treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors
assume any liability for any injury and/or damage to persons or property as a matter of products
liability, negligence, or otherwise or from any use or operation of any methods, products, instructions,
or ideas contained in the material herein.
Previous editions copyrighted 2013, 2009, 2004, 2000, 1995
ISBN: 978-0-323-48048-2
Executive Content Strategist: Dolores Meloni
Senior Content Development Specialist: Jennifer Ehlers
Publishing Services Manager: Catherine Albright Jackson
Senior Project Manager: Doug Turner
Designer: Margaret Reid
Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1
CLINICAL
ECHOCARDIOGRAPHY
, SIXTH EDITION
TEXTBOOK of
CLINICAL
ECHOCARDIOGRAPHY
Catherine M. Otto, MD
J. Ward Kennedy-Hamilton Endowed Chair in Cardiology
Professor of Medicine
University of Washington School of Medicine;
Director, Heart Valve Disease Clinic;
Associate Director, Echocardiography Laboratory
University of Washington Medical Center
Seattle, Washington
, 1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
TEXTBOOK OF CLINICAL ECHOCARDIOGRAPHY: SIXTH EDITION ISBN: 978-0-323-48048-2
Copyright © 2018 by Elsevier, Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or
mechanical, including photocopying, recording, or any information storage and retrieval system, without
permission in writing from the Publisher. Details on how to seek permission, further information about the
Publisher’s permissions policies, and our arrangements with organizations such as the Copyright Clearance
Center and the Copyright Licensing Agency can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher
(other than as may be noted herein).
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience
broaden our understanding, changes in research methods, professional practices, or medical treatment
may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating
and using any information, methods, compounds, or experiments described herein. In using such
information or methods, they should be mindful of their own safety and the safety of others, including
parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the
most current information provided (i) on procedures featured or (ii) by the manufacturer of each
product to be administered, to verify the recommended dose or formula, the method and duration of
administration, and contraindications. It is the responsibility of practitioners, relying on their own
experience and knowledge of their patients, to make diagnoses, to determine dosages and the best
treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors
assume any liability for any injury and/or damage to persons or property as a matter of products
liability, negligence, or otherwise or from any use or operation of any methods, products, instructions,
or ideas contained in the material herein.
Previous editions copyrighted 2013, 2009, 2004, 2000, 1995
ISBN: 978-0-323-48048-2
Executive Content Strategist: Dolores Meloni
Senior Content Development Specialist: Jennifer Ehlers
Publishing Services Manager: Catherine Albright Jackson
Senior Project Manager: Doug Turner
Designer: Margaret Reid
Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1
