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PNR 105 EXAM 2 (CH 5, 6, 8, 9, 10, 11) QUESTIONS COMPLETE WITH 100% VERIFIED ANSWERS

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PNR 105 EXAM 2 (CH 5, 6, 8, 9, 10, 11) QUESTIONS COMPLETE WITH 100% VERIFIED ANSWERS .Diuretics - ANSWERS-Classified into four groups: Thiazides, Thiazide-like sulfonamides, loop diuretics, potassium sparing diuretics .Thiazide and Thiazide-like diuretics - ANSWERS-Most commonly used type of diuretic and often are first line in the management of High blood Pressure. Thiazide (HCTZ), Thiazide like (Indapamide, metolazone). Potassium wasting .Loop diuretics - ANSWERS-Potassium wasting. Most powerful of the diuretics. (Bumetanide, furosemide [Lasix]) .Potassium sparing - ANSWERS-Increases the excretion of water and sodium, leading to increased urine output without loss of potassium. (Amiloride, Spironolactone [Aldactone], Triamterene) .Thiazide side effects - ANSWERS-Urinary frequency, dry mouth, increased thirst, CAN CAUSE INCREASE IN URIC ACID, which can cause flare ups of gout .Phenazopyridine - ANSWERS-Bladder anesthetic. Controls symptoms of urinary irritation including BURNING, PAIN, and urinary frequency that often results from acute UTI. CANNOT cure UTI .Phenazopyridine side effects - ANSWERS-Turns urine orange-red color that can stain toilet and clothing .HDL - ANSWERS-"Good cholesterol". Protective. Removes cholesterol from the blood and transports it to the liver. .LDL - ANSWERS-"Bad cholesterol". Harmful. Major contributors to the onset and progression of heart disease. .Antihyperlipidemic drugs (HMG-CoA reductase inhibitors) - ANSWERS-Also called STATINS! Lowers blood LDL levels by slowing cholesterol production by the liver. STATINS ARE MOST EFFECTIVE FOR LOWERING LDL LEVELS AND RAISING HDL LEVELS. They do NOT remove cholesterol from the blood. (Atorvastatin, Pravastatin). Review liver function tests before administering. CONTRAINDICATED IN PREGNANT WOMEN .Rhabdomyolysis - ANSWERS-Muscle breakdown. May occur with higher doses of statins. Can be life threatening. S&S: muscle soreness, TEA colored urine. .Selective cholesterol absorption inhibitors - ANSWERS-Stays in the intestinal wall and acts on the epithelial cells to limit the absorption of cholesterol from food and from other sources in the body .Fibric Acid Derivatives (Fibrates) - ANSWERS-Gemfibrozil and fenofibrate are the preferred drugs. Highly effective at lowering triglyceride levels and increasing

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PNR 105 EXAM 2 (CH 5, 6, 8, 9, 10,
11) QUESTIONS COMPLETE WITH 100%
VERIFIED ANSWERS


\.Diuretics - ANSWERS✔-Classified into four groups: Thiazides, Thiazide-like
sulfonamides, loop diuretics, potassium sparing diuretics



\.Thiazide and Thiazide-like diuretics - ANSWERS✔-Most commonly used type of
diuretic and often are first line in the management of High blood Pressure.
Thiazide (HCTZ), Thiazide like (Indapamide, metolazone). Potassium wasting



\.Loop diuretics - ANSWERS✔-Potassium wasting. Most powerful of the diuretics.
(Bumetanide, furosemide [Lasix])



\.Potassium sparing - ANSWERS✔-Increases the excretion of water and sodium,
leading to increased urine output without loss of potassium. (Amiloride,
Spironolactone [Aldactone], Triamterene)



\.Thiazide side effects - ANSWERS✔-Urinary frequency, dry mouth, increased
thirst, CAN CAUSE INCREASE IN URIC ACID, which can cause flare ups of gout



\.Phenazopyridine - ANSWERS✔-Bladder anesthetic. Controls symptoms of urinary
irritation including BURNING, PAIN, and urinary frequency that often results from
acute UTI. CANNOT cure UTI

, \.Phenazopyridine side effects - ANSWERS✔-Turns urine orange-red color that can
stain toilet and clothing



\.HDL - ANSWERS✔-"Good cholesterol". Protective. Removes cholesterol from the
blood and transports it to the liver.



\.LDL - ANSWERS✔-"Bad cholesterol". Harmful. Major contributors to the onset
and progression of heart disease.



\.Antihyperlipidemic drugs (HMG-CoA reductase inhibitors) - ANSWERS✔-Also
called STATINS! Lowers blood LDL levels by slowing cholesterol production by the
liver. STATINS ARE MOST EFFECTIVE FOR LOWERING LDL LEVELS AND RAISING HDL
LEVELS. They do NOT remove cholesterol from the blood. (Atorvastatin,
Pravastatin). Review liver function tests before administering. CONTRAINDICATED
IN PREGNANT WOMEN



\.Rhabdomyolysis - ANSWERS✔-Muscle breakdown. May occur with higher doses
of statins. Can be life threatening. S&S: muscle soreness, TEA colored urine.



\.Selective cholesterol absorption inhibitors - ANSWERS✔-Stays in the intestinal
wall and acts on the epithelial cells to limit the absorption of cholesterol from
food and from other sources in the body



\.Fibric Acid Derivatives (Fibrates) - ANSWERS✔-Gemfibrozil and fenofibrate are
the preferred drugs. Highly effective at lowering triglyceride levels and increasing

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