Solutions
A genetic test to detect predisposition to cancer would likely
examine the APC gene for involvement in which type(s) of
cancer? Correct Answers colorectal only
A population of viruses with similar characteristics is called a
________. Correct Answers class
A primary transcript in the nucleus of a eukaryotic cell is _____
the functional mRNA, while a primary transcript in a
prokaryotic cell is _____ the functional mRNA. Correct
Answers larger than; the same size as
A researcher found a method she could use to manipulate and
quantify methylation in embryonic cells in culture.
One of her colleagues suggested she try increased methylation
of C nucleotides in the DNA of promoters of a mammalian
system. Which of the following results would she most likely
see? Correct Answers inactivation of the selected genes
A virus consisting of a single strand of RNA, which is reverse
transcribed into complementary DNA, is referred to as a
________. Correct Answers retrovirus
Accuracy in the translation of mRNA into the primary structure
of a polypeptide depends on specificity in the ________. Correct
Answers binding of the anticodon to the codon and the
attachment of amino acids to tRNAs
, After the first replication was observed in their experiments
testing the nature of DNA replication, Meselson and Stahl could
be confident of which of the following conclusions? Correct
Answers Replication is not conservative.
An original section of DNA has the base sequence
AGCGTTACCGT. A mutation in this DNA strand results in the
base sequence AGGCGTTACCGT. What type of mutation does
this change represent? Correct Answers frameshift mutation
At one point, as a cell carried out its day-to-day activities, the
nucleotides GAT were paired with the nucleotides CUA. This
pairing occurred __________ Correct Answers during
transcription
DNA contains the template needed to copy itself, but it has no
catalytic activity in cells. What catalyzes the formation of
phosphodiester bonds between adjacent nucleotides in the DNA
polymer being formed during DNA replication? Correct
Answers DNA polymerase
For a science fair project, two students decided to repeat the
Hershey and Chase experiment, with modifications. They
decided to radioactively label the nitrogen of the DNA, rather
than the phosphate. They reasoned that each nucleotide has only
one phosphate and two to five nitrogen atoms. Thus, labeling the
nitrogen atoms would provide a stronger signal than labeling the
phosphates. Why won't this experiment work? Correct Answers
Amino acids (and thus proteins) also have nitrogen atoms; thus,
the radioactivity would not distinguish between DNA and
proteins.