Update ) Questions & Answers
{Grade A} 100% Correct
•There are 4 types of receptors that drugs interact with? - correct answer •Ligand
gated ion channels
•G protein coupled receptors
•Enzyme linked receptor
Intracellular receptor
The receptor that the drug interacts with determines? - correct answer the action of
the drug
Pharmacologic effect: - correct answer •The effect that a drug has on the cell
• Effect increases with dose, until...
,•Emax: Effect of the drug increases until all receptors are occupied by the drug (see
graph)
•Cells can regulate the number of receptors that are on the cell surface
Every time you give more BP medicine? - correct answer the receptors become
saturated, so the effect will be smaller and smaller until the full effect of the medicine
is gone. That's why sometimes we must approach more than 1 type of drugs to fix a
problem.
Agonist - correct answer mimic biologic effect or potentiate effects - helps very well
with pain
Partial Agonist - correct answer -potentiates biological effect (but not as strong as
true agonist) - not perfect - but helps reduce pain with no as much euphoria from
narcan (in case someone wants to get clean)
,Inverse agonist - correct answer binds to same receptor, but produces opposite effect
- pt would be in pain
Antagonist - correct answer competes for or blocks the agonist from binding -
NARCAN - blocks 100% of the receptors, so morphine or any other med can't connect.
What determines how a patient responds to a drug? - correct answer - Age
- Gender
- Ethnicity
- Genetic make-up
- Disease (severity, progression)
- Lifestyle
- Other drugs/ illnesses
, Pharmacogenetics - correct answer the study of how genetic variation affects an
individual's response to drugs
Pharmacogenomics - correct answer the study of how genetic inheritance affects the
body's response to drugs
•Nursing responsibilities when administering drugs - correct answer •Name of drug
and classification
•Intended use
•Effect on body
•Contraindications
•Special considerations
•Side effects
•Patient specific
•How supplied