NURS 5357 Neurobiology Exam 1 - Updated Summer
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All of the following are true about the hippocampus except
that it: - Answer-Is disrupted by frontal lobotomy
Which of the following statements is true about the
cerebellum: - Answer-Has been implicated in autism.
Cytokines are involved with all of the following except: -
Answer-identifying T. pallidum
Which of the following is a possible explanation for
schizophrenia: - Answer-Excessive pruning
Possible explanations for the role of thyroid hormone in
mood disorders include all of the following except: -
Answer-Changes in GR's
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All of the following are plausible theories on the etiology of
schizophrenia except? - Answer-Dopamine hypothesis
Auditory hallucinations have been shown to activate which
region on fMRI? - Answer-Superior temporal lobe
All of the following suggest white matter impairment in
schizophrenia except? - Answer-Significantly reduced
white matter volume
Evidence that GABA interneurons are impaired in
schizophrenia - Answer-Reduced GAD67
All of the following support the reduced neuropil
hypothesis except? - Answer-oligodendrocyte dysfunction
Evidence that schizophrenia is a biological disorder
includes all of the following except? - Answer-Gliosis in the
prefrontal cortex
What are the three major hypotheses of psychosis and
their neurotransmitter networks? - Answer-Dopamine
theory - hyperactive dopamine at D2 receptors in the
mesolimbic pathway
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Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the
cortex
Briefly explain the dopamine hypothesis of the positive
and negative symptoms of schizophrenia. - Answer-The
dopamine hypothesis of schizophrenia consists of:
There is too much dopamine activity in the mesolimbic
dopamine pathway, which leads to positive symptoms
(such as hallucinations and delusions).
There is also too little dopamine activity in the
mesocortical dopamine pathway, which leads to negative
symptoms (such as blunting of affect, poverty of speech,
anhedonia, and so on).
What pathway is responsible for regulating dopamine in
the hypothalamus and affects the release of prolactin? -
Answer-Tuberoinfundibular pathway
Drug-induced Parkinson's is caused by a decrease of
dopamine in what pathway? - Answer-Nigrostriatal
pathway