PHARMACOLOGY-NCM 106 QUESTIONS AND ANSWERS
• The name selected by the original manufacturer based on the chemical structure of the drug is the:
A. Chemical name
B. Drug name
C. Generic name
D. Trade name
Rationale: Generic name is the identification of the drug as named by the manufacturer basing from
the chemical structure of the drug, while chemical name is for the chemical structure of the
compound. And lastly the trade name comes from the company who produces the drug.
• The interaction of one drug increased by the presence of a second drug is known as:
A. Potentiation
B.Addictive effects
C.Antagonist
D. Synergism
Rationale: One of the drug to drug interactions is the potentiation, this is answer is to be
considered among the rest because by definition, one drug potentiates the other, in other words the
effectiveness of one drug is being increased once combined with another.
• When two drugs given together have an effect equal to the sum of their respective effects,
the interaction is known as:
A. Potentiated
B. Antagonized
C. Agonist
D. Additive
Rationale: From the root word itself, “Add”, by definition once two drug is being administered the
effectiveness is the sum of their respective effects.
• When a drug is 50% protein bound, it means that:
A. 50% of the drug destroys protein
B. 50% of the dose is at work
C. 50% of the drug is excreted in the kidneys
D. Protein must be restricted in the diet
Rationale: There are many metabolic activities within the body that uses protein as a resource of a
process, however answers A,C, and D does not represent any of these actions done by a 50% protein
bound drug. What it does mean is that 50% is of the dose is at work.
• Safety of a drug is determined by the degree between:
A. Therapeutic and toxic doses
B. Potency and efficacy
C. Subtherapeutic and toxic levels
D. Side and adverse effects
Rationale: Among the rest of the choices what mostly speaks about the safety of the drug is
therapeutic and toxic doses, potency and efficicacy do not speaks about safety same with side and
adverse effects which are part of the drug’s responses in the body. .
• When a drug binds to a receptor to produce a pharmacologic effect, the drug may be called a(n):
A. Agonist
B. Antagonist
C. Blocker
D. Accelerator
, PHARMACOLOGY-NCM 106 QUESTIONS AND ANSWERS
Rationale: The action of a drug that binds or connect itself in a receptor to stimulate a biological
response is called Agonist.
• Distribution is affected by:
A. Biotransformation
B. Excretion
C. Protein binding
D. Lipid binding
Rationale: The answer is protein binding because it is the way or manner how drug is being
distributed in the body, while the other two processes, biotransformation and excretion do not affect
drug distribution.
• An unexpected effect of the drug is known as a(n):
A. Side effect
B. Adverse effect
C. Toxic reaction
D. Allergic reaction
Rationale: Side effects are known reaction of the drugs while adverse effects are undesirable and
unpredictable reactions of a drug.
• When performing an assessment about medication, the drug history should include:
A. Complete vital signs
B. Client’s goal of therapy
C. Reason for medication
D. Administration of OTC medications
Rationale: Choice D is the most accurate because it is needed in the assessment to inform the client
if she is currently under OTC medications that their effects are going to be minimized.
• The volume of SC medication must be no more than:
A. 0.5 mL
B. 1.0 mL
C. 1.5 mL
D. 3.0 mL
Rationale: Drug consideration, no amount higher than 0.1mL is to be injected at the SC.
• Which of the following muscles is a possible site for IM injections?
A. Outer aspect of the hip
B. Shoulder
C. Vastus gluteus
D. Vastus lateralis
Rationale: Aside from the deltoid muscle located in the upper outer shoulder, Vastus lateralis is also
a desirable site for IM injections.
• When deciding on what time of day to give medications, the nurse pays closest attention to
the client’s habits regarding:
A. Eating
B. Sleeping
C. Elimination
D. Activity
Rationale: This consideration is important for this affects the drug’s efficacy and administration.
Knowing the clients eating habits or diet will allow the nurse to do necessary inteventions with
regards to drug administration.
• The client’s ability to take oral medications will be hindered by:
A. Age
B. Dental caries
C. Dysphagia
D. Lifestyle
Rationale: One of the common routes of administration is oral route, this can be hindered by the
condition called dysphagia which is a medial term for difficulty in swallowing.
• The name selected by the original manufacturer based on the chemical structure of the drug is the:
A. Chemical name
B. Drug name
C. Generic name
D. Trade name
Rationale: Generic name is the identification of the drug as named by the manufacturer basing from
the chemical structure of the drug, while chemical name is for the chemical structure of the
compound. And lastly the trade name comes from the company who produces the drug.
• The interaction of one drug increased by the presence of a second drug is known as:
A. Potentiation
B.Addictive effects
C.Antagonist
D. Synergism
Rationale: One of the drug to drug interactions is the potentiation, this is answer is to be
considered among the rest because by definition, one drug potentiates the other, in other words the
effectiveness of one drug is being increased once combined with another.
• When two drugs given together have an effect equal to the sum of their respective effects,
the interaction is known as:
A. Potentiated
B. Antagonized
C. Agonist
D. Additive
Rationale: From the root word itself, “Add”, by definition once two drug is being administered the
effectiveness is the sum of their respective effects.
• When a drug is 50% protein bound, it means that:
A. 50% of the drug destroys protein
B. 50% of the dose is at work
C. 50% of the drug is excreted in the kidneys
D. Protein must be restricted in the diet
Rationale: There are many metabolic activities within the body that uses protein as a resource of a
process, however answers A,C, and D does not represent any of these actions done by a 50% protein
bound drug. What it does mean is that 50% is of the dose is at work.
• Safety of a drug is determined by the degree between:
A. Therapeutic and toxic doses
B. Potency and efficacy
C. Subtherapeutic and toxic levels
D. Side and adverse effects
Rationale: Among the rest of the choices what mostly speaks about the safety of the drug is
therapeutic and toxic doses, potency and efficicacy do not speaks about safety same with side and
adverse effects which are part of the drug’s responses in the body. .
• When a drug binds to a receptor to produce a pharmacologic effect, the drug may be called a(n):
A. Agonist
B. Antagonist
C. Blocker
D. Accelerator
, PHARMACOLOGY-NCM 106 QUESTIONS AND ANSWERS
Rationale: The action of a drug that binds or connect itself in a receptor to stimulate a biological
response is called Agonist.
• Distribution is affected by:
A. Biotransformation
B. Excretion
C. Protein binding
D. Lipid binding
Rationale: The answer is protein binding because it is the way or manner how drug is being
distributed in the body, while the other two processes, biotransformation and excretion do not affect
drug distribution.
• An unexpected effect of the drug is known as a(n):
A. Side effect
B. Adverse effect
C. Toxic reaction
D. Allergic reaction
Rationale: Side effects are known reaction of the drugs while adverse effects are undesirable and
unpredictable reactions of a drug.
• When performing an assessment about medication, the drug history should include:
A. Complete vital signs
B. Client’s goal of therapy
C. Reason for medication
D. Administration of OTC medications
Rationale: Choice D is the most accurate because it is needed in the assessment to inform the client
if she is currently under OTC medications that their effects are going to be minimized.
• The volume of SC medication must be no more than:
A. 0.5 mL
B. 1.0 mL
C. 1.5 mL
D. 3.0 mL
Rationale: Drug consideration, no amount higher than 0.1mL is to be injected at the SC.
• Which of the following muscles is a possible site for IM injections?
A. Outer aspect of the hip
B. Shoulder
C. Vastus gluteus
D. Vastus lateralis
Rationale: Aside from the deltoid muscle located in the upper outer shoulder, Vastus lateralis is also
a desirable site for IM injections.
• When deciding on what time of day to give medications, the nurse pays closest attention to
the client’s habits regarding:
A. Eating
B. Sleeping
C. Elimination
D. Activity
Rationale: This consideration is important for this affects the drug’s efficacy and administration.
Knowing the clients eating habits or diet will allow the nurse to do necessary inteventions with
regards to drug administration.
• The client’s ability to take oral medications will be hindered by:
A. Age
B. Dental caries
C. Dysphagia
D. Lifestyle
Rationale: One of the common routes of administration is oral route, this can be hindered by the
condition called dysphagia which is a medial term for difficulty in swallowing.
