,. ENDOCRINE SYSTEM
I I
1. A I predominant I effect I of I a I prolonged I excessive I growth I hormone I level I is:
A) short I stature I with I obesity.
B) high I androgen I hormone I levels.
C) increased I blood I glucose I levels.
D) insulin-like I growth I factor I (IGF) I depletion.
2. The I most I common I cause I of I hypothyroidism I is:
A) goiter.
B) myxedema.
C) thyroidectomy.
D) autoimmune I thyroiditis.
,3. Thyroid I hormone I deficit , I which I alters I the Ifunction I of I all
I major Iorgans Iin Ithe Ibody.
A) decreases I metabolism
B) increases I protein I synthesis
C) causes I vitamin I deficiencies
D) enhances I absorption I of I glucose
4. The I most I common I cause I of I thyrotoxicosis I is I Graves I disease, I which I has
I the Idistinguishing I characteristic I of in Iaddition Ito Ia Idiffuse Igoiter.
A) muscle I fatigue
B) facial I myxedema
C) ophthalmopathy
D) decreased I cholesterol
5. The I major I adrenal I cortical I hormones I are I steroids I and I are I synthesized
I from Iacetate Iand:
A) ACTH.
B) albumin.
C) amino I acids.
D) cholesterol.
6. Primary I adrenal I insufficiency I is I manifested I by:
A) truncal I obesity I and I edema.
B) hypokalemia I and I hypervolemia.
C) hyponatremia I and I hypoglycemia.
D) hypopigmentation I and I hypertension.
7. One I of I the I earliest I signs I of I Cushing I syndrome I is I the I loss I of I variable
I diurnal Isecretion Iof Icortisol-releasing Ihormone I(CRH) Iand:
A) GH.
, B) TSH.
C) DHEA.
D) ACTH.
8. The I iatrogenic I form I of I Cushing I syndrome I is I caused I by:
A) long-term I cortisone I therapy.
B) pituitary I tumor-secreting I ACTH.
C) benign I or I malignant I adrenal I tumor.
D) ectopic I ACTH I secreting I lung I tumor.
9. The I major I manifestations I of I Cushing I syndrome I include:
A) excessive I salt I loss.
B) muscle I hypertrophy.
C) overt I diabetes I mellitus.
D) hair I and I weight I loss.
10 The I immune I suppressive I and I anti-inflammatory I effects I of I cortisol I cause:
.
A) moderate I insulin I resistance.
B) increased I capillary I permeability.
C) increased I cell-mediated I immunity.
D) inhibition I of I prostaglandin I synthesis.
11 Which I of I the I following I individuals I is I experiencing I the I effects I of I a I primary
. endocrine I disorder?
A) A I patient I with I adrenal I cortical I insufficiency I due I to I pituitary
I hyposecretion Iof IACTH
B) A I patient I who I has I hypothyroidism I as I a I result I of I low I TSH I production
C) A I patient I whose I dysfunctional I hypothalamus I has I resulted I in
I endocrine Iimbalances
I I
1. A I predominant I effect I of I a I prolonged I excessive I growth I hormone I level I is:
A) short I stature I with I obesity.
B) high I androgen I hormone I levels.
C) increased I blood I glucose I levels.
D) insulin-like I growth I factor I (IGF) I depletion.
2. The I most I common I cause I of I hypothyroidism I is:
A) goiter.
B) myxedema.
C) thyroidectomy.
D) autoimmune I thyroiditis.
,3. Thyroid I hormone I deficit , I which I alters I the Ifunction I of I all
I major Iorgans Iin Ithe Ibody.
A) decreases I metabolism
B) increases I protein I synthesis
C) causes I vitamin I deficiencies
D) enhances I absorption I of I glucose
4. The I most I common I cause I of I thyrotoxicosis I is I Graves I disease, I which I has
I the Idistinguishing I characteristic I of in Iaddition Ito Ia Idiffuse Igoiter.
A) muscle I fatigue
B) facial I myxedema
C) ophthalmopathy
D) decreased I cholesterol
5. The I major I adrenal I cortical I hormones I are I steroids I and I are I synthesized
I from Iacetate Iand:
A) ACTH.
B) albumin.
C) amino I acids.
D) cholesterol.
6. Primary I adrenal I insufficiency I is I manifested I by:
A) truncal I obesity I and I edema.
B) hypokalemia I and I hypervolemia.
C) hyponatremia I and I hypoglycemia.
D) hypopigmentation I and I hypertension.
7. One I of I the I earliest I signs I of I Cushing I syndrome I is I the I loss I of I variable
I diurnal Isecretion Iof Icortisol-releasing Ihormone I(CRH) Iand:
A) GH.
, B) TSH.
C) DHEA.
D) ACTH.
8. The I iatrogenic I form I of I Cushing I syndrome I is I caused I by:
A) long-term I cortisone I therapy.
B) pituitary I tumor-secreting I ACTH.
C) benign I or I malignant I adrenal I tumor.
D) ectopic I ACTH I secreting I lung I tumor.
9. The I major I manifestations I of I Cushing I syndrome I include:
A) excessive I salt I loss.
B) muscle I hypertrophy.
C) overt I diabetes I mellitus.
D) hair I and I weight I loss.
10 The I immune I suppressive I and I anti-inflammatory I effects I of I cortisol I cause:
.
A) moderate I insulin I resistance.
B) increased I capillary I permeability.
C) increased I cell-mediated I immunity.
D) inhibition I of I prostaglandin I synthesis.
11 Which I of I the I following I individuals I is I experiencing I the I effects I of I a I primary
. endocrine I disorder?
A) A I patient I with I adrenal I cortical I insufficiency I due I to I pituitary
I hyposecretion Iof IACTH
B) A I patient I who I has I hypothyroidism I as I a I result I of I low I TSH I production
C) A I patient I whose I dysfunctional I hypothalamus I has I resulted I in
I endocrine Iimbalances
