Advanced Pharmacology WGU D116 Unit 8 Prerequisite
pretest Exam training Questions with Rated A + solution
Latest 2025/2026
Which abx should be avoided in a patient with hx of allergic reaction to the abx
amoxicillin? - correct answer Cefuroxime (Ceftin)
If a pt has a hx of an allergic reaction to a penicillin abx, cephalosporin antibiotics
should be given cautiously
Which abx has potential adverse effects of tendon rupture, cardiac arrhythmias, or
paresthesias? - correct answer Fluoroquinolones
Ciprofloxacin
Gram negative bacteria are more difficult to treat due to which of the following
characteristics? - correct answer Outer lipopolysaccharide membrane
Presence of porin channels
Presence of endo/exotoxins
Which generation of the cephalosporin group are best coverage for gram negative
bacteria? - correct answer Third and fourth cover gram-negative pathogens more
broadly
On a gram stain, which 2 pathogens appears as cocci in chains? - correct answer
Group A streptococcus
Streptococcus pneumoniae
,Which abx is NOT considered a beta-lactam antibiotic? - correct answer Metronidazole
(flagyl)
Benadryl may be required to reduce erthroderma associated with which one of the
following drugs? - correct answer Vancomycin
A disulfiram reaction can occur if alcohol is consumed while taking which abx? - correct
answer Metronidazole
Flulike symptoms is with disulfiram reaction
A serum trough level should be measured in a patient receiving vancomycin when? -
correct answer 30 mins before the 4th dose
Optimal dose between 10-20 mcg/ml
The provider orders 20 mg of hydrocortisone orally once each day.
At what time should the drug be administered? - correct answer 8AM
To allow the adrenals to recover, dose should be given before 9AM
A patient has seasonal allergies and needs an antihistamine to control symptoms. The
patient likes to have wine with dinner occasionally and wants to know which
antihistamine will be the safest to take.
Which medication will be the safest for the patient to take? - correct answer
Fexofenadine (allergra) 2nd-generation H1-receptor blocker (antagonist)
Least sedating so it is least likely to have synergistic effects with alcohol
A 60-year-old female patient is about to begin long-term therapy with a glucocorticoid.
, What will be important for minimizing the risk of osteoporosis? - correct answer
Calcium and vitamin D supplements
Can help minimize the patient's risk of developing osteoporosis
A patient is using a high concentration keratolytic agent containing 20 percent salicylic
acid to remove warts.
What should the provider teach this patient? - correct answer "Systemic effects may
occur with this medication"
Salicylic acid is readily absorbed through the skin, and systemic toxicity can result
Tinnitus is a s/s of systemic toxicity
Tissue injury is likely in any concentration above 6%
Peeling and drying are NOT desired effects of salicylic acid
A patient with severe psoriasis will begin taking acitretin. The provider obtains a health
history and learns that the patient takes a combination oral contraceptive (OCP).
What should the provider do? - correct answer Counsel the pt to use another form of
birth control along with the combination oral contraceptive (OCP)
Acitretin (like accutane) is contraindicated during pregnancy and can reduce the
effectiveness of progestin-only oral contraceptives
Pts need to use 2 reliable forms of birth control
A patient has severe acne that has been refractory to treatment. The patient is taking
tetracycline and using topical tretinoin and has been applying benzoyl peroxide twice
pretest Exam training Questions with Rated A + solution
Latest 2025/2026
Which abx should be avoided in a patient with hx of allergic reaction to the abx
amoxicillin? - correct answer Cefuroxime (Ceftin)
If a pt has a hx of an allergic reaction to a penicillin abx, cephalosporin antibiotics
should be given cautiously
Which abx has potential adverse effects of tendon rupture, cardiac arrhythmias, or
paresthesias? - correct answer Fluoroquinolones
Ciprofloxacin
Gram negative bacteria are more difficult to treat due to which of the following
characteristics? - correct answer Outer lipopolysaccharide membrane
Presence of porin channels
Presence of endo/exotoxins
Which generation of the cephalosporin group are best coverage for gram negative
bacteria? - correct answer Third and fourth cover gram-negative pathogens more
broadly
On a gram stain, which 2 pathogens appears as cocci in chains? - correct answer
Group A streptococcus
Streptococcus pneumoniae
,Which abx is NOT considered a beta-lactam antibiotic? - correct answer Metronidazole
(flagyl)
Benadryl may be required to reduce erthroderma associated with which one of the
following drugs? - correct answer Vancomycin
A disulfiram reaction can occur if alcohol is consumed while taking which abx? - correct
answer Metronidazole
Flulike symptoms is with disulfiram reaction
A serum trough level should be measured in a patient receiving vancomycin when? -
correct answer 30 mins before the 4th dose
Optimal dose between 10-20 mcg/ml
The provider orders 20 mg of hydrocortisone orally once each day.
At what time should the drug be administered? - correct answer 8AM
To allow the adrenals to recover, dose should be given before 9AM
A patient has seasonal allergies and needs an antihistamine to control symptoms. The
patient likes to have wine with dinner occasionally and wants to know which
antihistamine will be the safest to take.
Which medication will be the safest for the patient to take? - correct answer
Fexofenadine (allergra) 2nd-generation H1-receptor blocker (antagonist)
Least sedating so it is least likely to have synergistic effects with alcohol
A 60-year-old female patient is about to begin long-term therapy with a glucocorticoid.
, What will be important for minimizing the risk of osteoporosis? - correct answer
Calcium and vitamin D supplements
Can help minimize the patient's risk of developing osteoporosis
A patient is using a high concentration keratolytic agent containing 20 percent salicylic
acid to remove warts.
What should the provider teach this patient? - correct answer "Systemic effects may
occur with this medication"
Salicylic acid is readily absorbed through the skin, and systemic toxicity can result
Tinnitus is a s/s of systemic toxicity
Tissue injury is likely in any concentration above 6%
Peeling and drying are NOT desired effects of salicylic acid
A patient with severe psoriasis will begin taking acitretin. The provider obtains a health
history and learns that the patient takes a combination oral contraceptive (OCP).
What should the provider do? - correct answer Counsel the pt to use another form of
birth control along with the combination oral contraceptive (OCP)
Acitretin (like accutane) is contraindicated during pregnancy and can reduce the
effectiveness of progestin-only oral contraceptives
Pts need to use 2 reliable forms of birth control
A patient has severe acne that has been refractory to treatment. The patient is taking
tetracycline and using topical tretinoin and has been applying benzoyl peroxide twice
