Immunology Exam 1 Questions and
Correct Answers
What are two examples of phagocytes? - <CORRECT ANSWER >>Neutrophils (PMN-polymorpho
nuclear) and Macrophages (MO)
True or false: Monocytes are precursors of macrophages. - <CORRECT ANSWER >>True.
Monocytes are found in blood but when they move into tissues, they are macrophages.
What cells are important for parasite control, allergy, and inflammation? - <CORRECT ANSWER
>>1. mast cell (release histamine when activated)
2. eosinophil (similar function as mast cell but arrive at scene later)
3. basophil (uncommon; function unknown)
4. dendritic cell (internalize pathogens & active T-cells & help initiate adaptive immune
response-serving as a bridge)
What are two types of lymphocytes? - <CORRECT ANSWER >>T cells and B cells.
T or F: Plasma cells are B-cells that actively secrete antibodies. - <CORRECT ANSWER >>True.
What is the effector function? - <CORRECT ANSWER >>A job that a cell has once it is activated
Some functions of the immune response include: - <CORRECT ANSWER >>a. recognition of the
pathogen or antigen
b. develop "effector" function
What are the main differences between innate immunity and adaptive immunity? - <CORRECT
ANSWER >>Innate immunity: quicker response, use less specific mechanisms to recognize
, pathogens, unable to eradicate the pathogen completely, doesn't provide immunity for
reinfection.
Define hematopoiesis. - <CORRECT ANSWER >>Hematopoiesis is the generation of blood cells.
T or F: Blood cells and certain tissue cells derive from a common hematopoietic stem cell. -
<CORRECT ANSWER >>True. It's pluripotent & self-renewing (can make many copies of itself)
Immune cells go through which pathways? - <CORRECT ANSWER >>Lymphoid and myeloid
pathways.
What are examples of granulocytes? - <CORRECT ANSWER >>neutrophils, basophils, and
eosinophils. They are polymorphonuclear leukocytes that reside in the blood.
What chemical signals drive the path the cell takes to its final fate? - <CORRECT ANSWER >>1.
colony stimulating factor (CSF) - GCSF (granulocyte colony stimulating factor) --> drives the
production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body? - <CORRECT ANSWER >>fetal liver or spleen,
and bone marrow (adults only)
What does lymphoid progenitor differentiate into? - <CORRECT ANSWER >>1. B cells
2. T cells
3. Natural Killer (NK) cells
What does myeloid progenitor differentiate into? - <CORRECT ANSWER >>1. basophils
2. eosinophils
Correct Answers
What are two examples of phagocytes? - <CORRECT ANSWER >>Neutrophils (PMN-polymorpho
nuclear) and Macrophages (MO)
True or false: Monocytes are precursors of macrophages. - <CORRECT ANSWER >>True.
Monocytes are found in blood but when they move into tissues, they are macrophages.
What cells are important for parasite control, allergy, and inflammation? - <CORRECT ANSWER
>>1. mast cell (release histamine when activated)
2. eosinophil (similar function as mast cell but arrive at scene later)
3. basophil (uncommon; function unknown)
4. dendritic cell (internalize pathogens & active T-cells & help initiate adaptive immune
response-serving as a bridge)
What are two types of lymphocytes? - <CORRECT ANSWER >>T cells and B cells.
T or F: Plasma cells are B-cells that actively secrete antibodies. - <CORRECT ANSWER >>True.
What is the effector function? - <CORRECT ANSWER >>A job that a cell has once it is activated
Some functions of the immune response include: - <CORRECT ANSWER >>a. recognition of the
pathogen or antigen
b. develop "effector" function
What are the main differences between innate immunity and adaptive immunity? - <CORRECT
ANSWER >>Innate immunity: quicker response, use less specific mechanisms to recognize
, pathogens, unable to eradicate the pathogen completely, doesn't provide immunity for
reinfection.
Define hematopoiesis. - <CORRECT ANSWER >>Hematopoiesis is the generation of blood cells.
T or F: Blood cells and certain tissue cells derive from a common hematopoietic stem cell. -
<CORRECT ANSWER >>True. It's pluripotent & self-renewing (can make many copies of itself)
Immune cells go through which pathways? - <CORRECT ANSWER >>Lymphoid and myeloid
pathways.
What are examples of granulocytes? - <CORRECT ANSWER >>neutrophils, basophils, and
eosinophils. They are polymorphonuclear leukocytes that reside in the blood.
What chemical signals drive the path the cell takes to its final fate? - <CORRECT ANSWER >>1.
colony stimulating factor (CSF) - GCSF (granulocyte colony stimulating factor) --> drives the
production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body? - <CORRECT ANSWER >>fetal liver or spleen,
and bone marrow (adults only)
What does lymphoid progenitor differentiate into? - <CORRECT ANSWER >>1. B cells
2. T cells
3. Natural Killer (NK) cells
What does myeloid progenitor differentiate into? - <CORRECT ANSWER >>1. basophils
2. eosinophils
