ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED
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to be diagnosed with MDD, you need one of two symptoms
Ans✓✓✓depressed mood; apathy/loss of interest
to be diagnosed with MDD, you need 4/7 symptoms
Ans✓✓✓weight/appetite changes; sleep disturbances; psychomotor;
fatigue; worthlessness; executive dysfunction; suicidal ideation
pharmacological management of MDD Ans✓✓✓SSRI, NDRI, SNRI,
TCAs, MAOI
SSRI MOA Ans✓✓✓selective serotonin reuptake inhibitor; increases
serotonin in body
NDRI MOA Ans✓✓✓norepinephrine dopamine reuptake inhibitor
SSRI use Ans✓✓✓antidepressant, anxiety (first line)
NRDI use Ans✓✓✓depression, smoking cessation
NRDI SE Ans✓✓✓weight loss, reduced appetite, insomnia, elevated BP
, SSRI SE Ans✓✓✓GI upset, n/v, sexual dysfunction
SNRI MOA Ans✓✓✓Serotonin norepinephrine reuptake inhibitor
SNRI uses Ans✓✓✓depression; somatic pain; co-occuring pain disorder
SNRI SE Ans✓✓✓GI upset, n/v, fatigue (take at night), weight loss,
sexual dysfunction
Trazodone, Remeron Ans✓✓✓depression; used when patient has sleep
dysfunction (initiating sleep)
Tricyclic (TCAs) MOA Ans✓✓✓increases all monoamines
TCA SE Ans✓✓✓weight gain, dry mouth, sedation, cardiac effects
MAOI Example Ans✓✓✓Nardil
MAOI consideration Ans✓✓✓tyramine free diet
MAOI major issue Ans✓✓✓hypertensive crisis