NURS 5315 ADVANCED PATHOPHYSIOLOGY
UTA 2026 EXAM 1 COMPLETE (138) CURRENT
TESTING QUESTIONS AND DETAILED
CORRECT ANSWERS (VERIFIED) TOP-RATED
A+.
NURS 5315
Prepare for your NURS 5315 Advanced Pathophysiology Exam 1
at University of Texas at Arlington with this focused study guide.
It covers cellular pathophysiology, genetic influences on
disease, inflammation, and alterations in body systems.
Emphasizes clinical reasoning, disease mechanisms, and
application of advanced pathophysiology concepts. Suitable for
graduate nursing students preparing for advanced
pathophysiology assessments.
Renin Angiotensin Aldosterone System (RAAS) ✓ ✓......
ANSWER ....... Activated by low blood volume. Low
blood volume --> renin --> angiotensinogen --> angiotensin 1
--> ACE (angiotensin converting enzyme) converts
angiotensin 1 to angiotensin 2 -->causes arterial
vasoconstriction --> release of aldosterone --> renal Na+
and H2O reabsorption and K+ excretion.
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Produces LESS urine and blood volume INCREASES.
Manages BP - when body constricts, BP increases
Normal plasma osmolality ✓ ✓...... ANSWER ....... 280-
295 mOsm/kg
Natriuretic hormones ✓ ✓...... ANSWER ....... ANP and
BNP. Hormones released from the heart to decrease blood
volume by promoting urinary excretion of Na+ and H2O.
Decreases blood volume. Opposite of RAAS.
How does a hypertonic solution alter osmolality? ✓ ✓......
ANSWER ....... Increases solute concentration, causing
INCREASED osmolality. Causes cells to SHRINK.
How does a hypotonic solution alter osmolality? ✓ ✓......
ANSWER ....... Intravascular space to become more
dilute, causes cells to SWELL.
Fluid volume deficit (dehydration) clinical manifestations ✓
✓...... ANSWER ....... Poor skin turgor, dry mucous
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membranes, sunken eyes, sunken fontanels (in babies),
decreased urine output, fatigue
Fluid volume excess (fluid retention) clinical manifestations
✓ ✓...... ANSWER ....... Edema, tight skin, puffiness of
eyes, rales or wet breath sounds
Edema is an accumulation of fluid where? ✓ ✓......
ANSWER ....... Interstitial space
Edema pathophysiology ✓ ✓...... ANSWER ....... 1.
Increased hydrostatic pressure
2. Decreased oncotic pressure
3. Increased capillary membrane permeability
4. Lymphatic channel obstruction
Edema clinical manifestations ✓ ✓...... ANSWER .......
Pitting, swelling, puffiness, limited movement in affected
area
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Liver disease and protein malnutrition can result in what? ✓
✓...... ANSWER ....... Decreased oncotic pressure
Glomerular disease, trauma victims, hemorrhage, burns,
and cirrhosis of the liver can result in what? ✓ ✓......
ANSWER ....... Decreased oncotic pressure
How does edema cause increased hydrostatic pressure? ✓
✓...... ANSWER ....... Venous obstruction --> increased
hydrostatic pressure --> fluid is pushed out of the vascular
space into the interstitial space
How does edema cause decreased oncotic pressure? ✓
✓...... ANSWER ....... Decreased plasma protein
production --> decreased oncotic pressure and osmotic
pressure --> fluid moves into the interstitium
How does edema cause increased capillary permeability?
✓ ✓...... ANSWER ....... Results from times of
inflammation (trauma, crushing injuries, burns, neoplastic
diseases, allergic reactions, infections). Increased capillary
permeability allows large amounts of fluid to escape and
enter the interstitial space.