Advanced Pharmacology Final Exam
Review UPDATED ACTUAL QUESTIONS
AND CORRECT ANSWERS
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin
therapy? - CORRECT ANSWER To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - CORRECT
ANSWER Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with?
- CORRECT ANSWER Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - CORRECT
ANSWER Aldosterone antagonist
Heparin exerts its therapeutic action by what? - CORRECT ANSWER Upregulating
the activity of one of the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an
anaphylactic reaction. - CORRECT ANSWER Mast cells liberate large doses of
histamine.
What are two systemic psoriasis medications? - CORRECT ANSWER Photo-therapy
and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage
I hypertension? - CORRECT ANSWER Thiazide diuretics
What is the effect of cardiac glycosides? - CORRECT ANSWER Digitalis glycosides
have a negative chronotropic effect on the cardiac muscle cells.
, Amenorrhea is the most common side effect of which birth control medication? - CORRECT
ANSWER Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-
receptor sites? - CORRECT ANSWER Atenolol (Tenormin)
What type of action does nitrates have on the body? - CORRECT ANSWER Reduction
in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients
with known coronary artery disease? - CORRECT ANSWER 100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - CORRECT
ANSWER Depressing phase 4 depolarization and lengthening phases 1 and 2
repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones
and re-establish eumetabolic state in a patient with Graves' disease? - CORRECT
ANSWER Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
insufficiency? - CORRECT ANSWER Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart
failure? - CORRECT ANSWER Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? - CORRECT
ANSWER Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker? - CORRECT
ANSWER Prazosin (Minipress)
Review UPDATED ACTUAL QUESTIONS
AND CORRECT ANSWERS
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin
therapy? - CORRECT ANSWER To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - CORRECT
ANSWER Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with?
- CORRECT ANSWER Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - CORRECT
ANSWER Aldosterone antagonist
Heparin exerts its therapeutic action by what? - CORRECT ANSWER Upregulating
the activity of one of the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an
anaphylactic reaction. - CORRECT ANSWER Mast cells liberate large doses of
histamine.
What are two systemic psoriasis medications? - CORRECT ANSWER Photo-therapy
and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage
I hypertension? - CORRECT ANSWER Thiazide diuretics
What is the effect of cardiac glycosides? - CORRECT ANSWER Digitalis glycosides
have a negative chronotropic effect on the cardiac muscle cells.
, Amenorrhea is the most common side effect of which birth control medication? - CORRECT
ANSWER Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-
receptor sites? - CORRECT ANSWER Atenolol (Tenormin)
What type of action does nitrates have on the body? - CORRECT ANSWER Reduction
in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients
with known coronary artery disease? - CORRECT ANSWER 100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - CORRECT
ANSWER Depressing phase 4 depolarization and lengthening phases 1 and 2
repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones
and re-establish eumetabolic state in a patient with Graves' disease? - CORRECT
ANSWER Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
insufficiency? - CORRECT ANSWER Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart
failure? - CORRECT ANSWER Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? - CORRECT
ANSWER Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker? - CORRECT
ANSWER Prazosin (Minipress)
