NUR 253 Exam 1 Questions With Complete Solutions
accepting Correct Answers indicates you understand the patient
- Saying yes
Antidepressant: MAOIs Correct Answers - Isocarboxazid
(Marplan)
- Phenelzine (Nardil)
- Selegiline (EMSAM)
- Tranylcypromine (Parnate)
Notes:
- Illustrates a principle that drugs can have a desired and
beneficial effect in the brain while at the same time having
possibly dangerous effects elsewhere in the body.
Tyramine: aged cheeses, pickled or smoked fish, and wine
- Liver can not break down tyramine - produces significant
vasoconstriction
- HYPERTENSIVE CRISIS
Contraindicated with concurrent use of any antidepressant and
sympathomimetic drugs (oral decongestant)
-Give patients list of foods that needs to be avoided.
Antidepressant: SNRIs Correct Answers - Venlafaxine
(Effexor) - more serotonergic agent at lower therapeutic doses,
norepinephrine reuptake blockade at higher doses.
Hypertension may be induced in about 5% (depending on
norepinephrine reuptake blockade)
, - Desvenlafaxine (Pristiq) - metabolite of venlafaxine.
- Duloxetine (Cymbalta):
Indicated for both depression and GAD; diabetic neuropathy;
fibromyalgia
Therapeutic effects on neuropathic pain (nerve injury and
dysfunction)
Notes:
- Increases both serotonin and norepinephrine
Antidepressants: SSRIs Correct Answers - Fluoxetine (Prozac) -
can lead to anorexic and antibulimic effects at higher doses
- Sertraline (Zoloft)
- Paroxetine (Paxil) - most anticholinergic
- Citalopram (Celexa)
- Escitalopram (Lexapro)
- Fluvoxamine (Luvox)
Notes:
- Comparable efficacy without eliciting the anticholinergic and
sedating side effects that limits patient compliance.
- Gi tract
Side effects:
- apathy and low libido
Antidepressants: Tricyclic antidepressants (TCAs) Correct
Answers Tricyclic antidepressants (TCAs):
accepting Correct Answers indicates you understand the patient
- Saying yes
Antidepressant: MAOIs Correct Answers - Isocarboxazid
(Marplan)
- Phenelzine (Nardil)
- Selegiline (EMSAM)
- Tranylcypromine (Parnate)
Notes:
- Illustrates a principle that drugs can have a desired and
beneficial effect in the brain while at the same time having
possibly dangerous effects elsewhere in the body.
Tyramine: aged cheeses, pickled or smoked fish, and wine
- Liver can not break down tyramine - produces significant
vasoconstriction
- HYPERTENSIVE CRISIS
Contraindicated with concurrent use of any antidepressant and
sympathomimetic drugs (oral decongestant)
-Give patients list of foods that needs to be avoided.
Antidepressant: SNRIs Correct Answers - Venlafaxine
(Effexor) - more serotonergic agent at lower therapeutic doses,
norepinephrine reuptake blockade at higher doses.
Hypertension may be induced in about 5% (depending on
norepinephrine reuptake blockade)
, - Desvenlafaxine (Pristiq) - metabolite of venlafaxine.
- Duloxetine (Cymbalta):
Indicated for both depression and GAD; diabetic neuropathy;
fibromyalgia
Therapeutic effects on neuropathic pain (nerve injury and
dysfunction)
Notes:
- Increases both serotonin and norepinephrine
Antidepressants: SSRIs Correct Answers - Fluoxetine (Prozac) -
can lead to anorexic and antibulimic effects at higher doses
- Sertraline (Zoloft)
- Paroxetine (Paxil) - most anticholinergic
- Citalopram (Celexa)
- Escitalopram (Lexapro)
- Fluvoxamine (Luvox)
Notes:
- Comparable efficacy without eliciting the anticholinergic and
sedating side effects that limits patient compliance.
- Gi tract
Side effects:
- apathy and low libido
Antidepressants: Tricyclic antidepressants (TCAs) Correct
Answers Tricyclic antidepressants (TCAs):
