Intervention, and Evidence-Based Management of
Immunodeficiency, Hypersensitivity Reactions,
Allergic Disorders, Post-Transplant Care,
Immunotherapy, and Acute Anaphylaxis with Focus
on T-Cell Function, Laboratory Interpretation,
Patient Teaching, and Delegation in Critical and
Outpatient Settings Exam Questions Verified and
Provided with A+ Graded Rationales Latest
Updated 2026
The nurse provides discharge instructions to a patient who has an immune deficiency involving
the T lymphocytes. Which health screening should the nurse include in the teaching plan for
this patient?
a. Screening for allergies
b. Screening for malignancies
c. Screening for antibody deficiencies
d. Screening for autoimmune disorders
ANS: B
Cell-mediated immunity is responsible for the recognition and destruction of cancer cells.
Allergic reactions, autoimmune disorders, and antibody deficiencies are mediated primarily by B
lymphocytes and humoral immunity.
A patient is being evaluated for possible atopic dermatitis. The nurse expects elevation of which
laboratory value?
a. IgE
b. IgA
c. Basophils
d. Neutrophils
ANS: A
Serum IgE is elevated in an allergic response (type 1 hypersensitivity disorders). The eosinophil
level will be elevated rather than neutrophil or basophil counts. IgA is located in body secretions
and would not be tested when evaluating a patient who has symptoms of atopic dermatitis.
, An older adult patient who is having an annual check-up tells the nurse, "I feel fine, and I don't
want to pay for all these unnecessary cancer screening tests!" Which information should the
nurse plan to teach this patient?
a. Consequences of aging on cell-mediated immunity
b. Decrease in antibody production associated with aging
c. Impact of poor nutrition on immune function in older people
d. Incidence of cancer-associated infections in older individuals
ANS: A
The primary impact of aging on immune function is on T cells, which are important for immune
surveillance and tumor immunity. Antibody function is not affected as much by aging. Poor
nutrition can also contribute to decreased immunity, but there is no evidence that it is a
contributing factor for this patient. Although some types of cancer are associated with specific
infections, this patient does not have an active infection.
A patient who collects honey to earn supplemental income has developed a hypersensitivity to
bee stings. Which statement, if made by the patient, would indicate a need for additional
teaching?
a. "I need to find a different way to earn extra money."
b. "I will take oral antihistamines before going to work."
c. "I will get a prescription for epinephrine and learn to self-inject it."
d. "I should wear a Medic-Alert bracelet indicating my allergy to bee stings."
ANS: B
Because the patient is at risk for bee stings and the severity of allergic reactions tends to
increase with added exposure to allergen, taking oral antihistamines will not adequately control
the patient's hypersensitivity reaction. The other patient statements indicate a good
understanding of management of the problem.
Which information about intradermal skin testing should the nurse teach to a patient with
possible allergies?
a. "Do not eat anything for about 6 hours before the testing."
b. "Take an oral antihistamine about an hour before the testing."
c. "Plan to wait in the clinic for 20 to 30 minutes after the testing."
d. "Reaction to the testing will take about 48 to 72 hours to occur."
ANS: C
Allergic reactions usually occur within minutes after injection of an allergen, and the patient will
be monitored for at least 20 minutes for anaphylactic reactions after the testing. Medications
that might modify the response, such as antihistamines, should be avoided before allergy