Antimicrobials Part 3 ACTUAL EXAM Review NEWEST COMPLETE
QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS)
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The cell walls of mycobacteria contain what?
Mycolic acid
Why are mycobacteria called acid fast bacilli?
Because they produce lipophilic cell walls that do not stain well with Gram
stain but once they are stained they do not lose the color even when made
acidic
-they appear red or pink
Mycobacteria infections cause what to grow?
Slow-growing granulomatous lesions
-these can occur anywhere in the body
What is the leading infectious cause of death worldwide?
Mycobacterium tuberculosis
-1/4 of the world's population is infected
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What are the other types of nontubercular mycobacterium?
-M. Avium
-M. Intracellulare
-M. Chelonae
-M. Abscessus
-M. Kansasii
-M. Fortuitum
-M. Leprae
T/F: Leprosy is a type of mycobacterium infection.
True
-caused by M. leprae
What drugs are used to treat mycobacterium?
-Ethambutol
-Isoniazid
-Pyrazinamide
-Rifabutin
-Rifampin
-Rifapentine
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What is the prototype drug for mycobacterium?
Isoniazid
What are the second line drugs for TB?
-Aminosalicylic acid
-Bedaquiline
-Capreomycin
-Cyclosporine
-Ethionamide
-Aminoglycosides
-Fluoroquinolones
-Macrolides
How long does TB treatment take?
Months to years
Latent TB can be treated for 9 months with?
Isoniazid
Latent TB can be treated for 3 months with?
12 once a week high dose isoniazid and rifapentine
How long is multi-drug resistant TB treated?
2 years
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What is extremely drug resistant TB (XDR-TB)?
Resistant to isoniazid and rifampin, all fluoroquinolones, and at least one of
the injectable second-line drugs
What can be used to treat XDR-TB?
-Clofazimine
-Linezolid
What are the first line agents for treating TB?
-Isoniazid
-Rifampin
-Ethambutol
-Pyrazinamide
T/F: Active TB always requires the use of multiple drugs, 3 more with proven in
vitro activity against the isolate.
True
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