First Aid USMLE Step 1: Neurology Exam
Questions with Answers
1. Describe the ba-- the* notochord* induces overlying ectoderm to ditterentiate into
neuroectoderm
sic embryological and form the neural plate (day 18)
process - the neural plate invaginates to form the *neural tube* and at the same
behind time, cells demarginated from the invaginating tube to form the
development *neural crest cells*
of the neural
tube
2. What are The alar and basal plates are basically the dorsal and ventral divisions of the
the basal neural tube below the sulcus limitans.
and alar
plates? The alar plate (dorsal) --> sensory neurons of the spinal
What do cord The basal plate (ventral) --> motor neurons of the
they give
rise to? spinal cord
3. With regard
1/
174
,to the
regions of
the
developing
brain correct
answer
What are the
three primary
vesicles of the
brain?
2/
174
, What are the 5 give rise to?
secondary
vesi- cles they 5. In general, what are neural tube defects?
give rise to?
Name the
adult
structures
that arise
from the walls
and cavi- ties
of the 5 sec-
ondary
vesicles.
4. What does
the
notochord
give rise to?
What does
the
neuroecto-
derm give
rise to?
What do the
neural crest
cells give rise
to?
What does the
mesoderm
3/
174
, give rise to?*
-microglia!
*In general, what are neural tube defects?*
-failure of the neuropores to fuse (occurs in the 4th week)
-results in a persistent connections between the amniotic cavity and spinal
canal
*What does the notochord give
rise to?
-the notochord gives rise
nucleus pulposus of the
intervertebral disc in adults
*What does the neuroectoderm
give rise to?*
---> the neural tube, which then
gives rise to
-CNS neurons
-ependymal cells (inner lining of
ventricles, makes CSF fluid)
-oligodendroglia
-astrocytes
*What do the neural crest cells
give rise to?*
-PNS neurons
-Schwann cells
*What does the mesoderm
4/
174
Questions with Answers
1. Describe the ba-- the* notochord* induces overlying ectoderm to ditterentiate into
neuroectoderm
sic embryological and form the neural plate (day 18)
process - the neural plate invaginates to form the *neural tube* and at the same
behind time, cells demarginated from the invaginating tube to form the
development *neural crest cells*
of the neural
tube
2. What are The alar and basal plates are basically the dorsal and ventral divisions of the
the basal neural tube below the sulcus limitans.
and alar
plates? The alar plate (dorsal) --> sensory neurons of the spinal
What do cord The basal plate (ventral) --> motor neurons of the
they give
rise to? spinal cord
3. With regard
1/
174
,to the
regions of
the
developing
brain correct
answer
What are the
three primary
vesicles of the
brain?
2/
174
, What are the 5 give rise to?
secondary
vesi- cles they 5. In general, what are neural tube defects?
give rise to?
Name the
adult
structures
that arise
from the walls
and cavi- ties
of the 5 sec-
ondary
vesicles.
4. What does
the
notochord
give rise to?
What does
the
neuroecto-
derm give
rise to?
What do the
neural crest
cells give rise
to?
What does the
mesoderm
3/
174
, give rise to?*
-microglia!
*In general, what are neural tube defects?*
-failure of the neuropores to fuse (occurs in the 4th week)
-results in a persistent connections between the amniotic cavity and spinal
canal
*What does the notochord give
rise to?
-the notochord gives rise
nucleus pulposus of the
intervertebral disc in adults
*What does the neuroectoderm
give rise to?*
---> the neural tube, which then
gives rise to
-CNS neurons
-ependymal cells (inner lining of
ventricles, makes CSF fluid)
-oligodendroglia
-astrocytes
*What do the neural crest cells
give rise to?*
-PNS neurons
-Schwann cells
*What does the mesoderm
4/
174
