Karch’s Focus on Nursing Pharmacology – Test Bank – Verified Questions and Answers

,Chapter 01 - Introduction to Drugs
A A A A A




AAnurseAworkingAinAradiologyAadministersAiodineAtoAaApatientAwhoAisAhavingAaAcomputedAtomographyA(C
T)Ascan.ATheAnurseAworkingAonAtheAoncologyAunitAadministersAchemotherapyAtoApatientsAwhoAhave
Acancer.AAtAtheAPublicAHealthADepartment,AaAnurseAadministersAaAmeasles-mumps-

rubellaA(MMR)AvaccineAtoAaA14-month-
oldAchildAasAaAroutineAimmunization.AWhichAbranchAofApharmacologyAbestAdescribesAtheAactionsAof
AallAthreeAnurses?




PharmacoeconomicsA


Pharmacotherapeutics


PharmacodynamicsAP
A




harmacokineticsA Ans:


B


Response:


PharmacologyAisAtheAstudyAofAtheAbiologicAeffectsAofAchemicals.ANursesAareAinvolvedAwithAclinicalAph
armacologyAorApharmacotherapeutics,AwhichAisAaAbranchAofApharmacologyAthatAdealsAwithAtheAusesAofA
drugsAtoAtreat,Aprevent,AandAdiagnoseAdisease.ATheAradiologyAnurseAisAadministeringAaAdrugAtoAhelpAdi
agnoseAaAdisease.ATheAoncologyAnurseAisAadministeringAaAdrugAtoAhelpAtreatAaAdisease.
PharmacoeconomicsAincludesAanyAcostsAinvolvedAinAdrugAtherapy.APharmacodynamicsAinvolvesAhowAa
AdrugAaffectsAtheAbodyAandApharmacokineticsAisAhowAtheAbodyAactsAonAtheAbody.




AAphysicianAhasAorderedAintramuscularA(IM)AinjectionsAofAmorphine,AaAnarcotic,AeveryA4AhoursAasAneededAf
orApainAinAaAmotorAvehicleAaccidentAvictim.ATheAnurseAisAawareAthisAdrugAhasAaAhighAabuseApotential
.
UnderAwhatAcategoryAwouldAmorphineAbeAclassified?


ScheduleAIAS


cheduleAIIAS


cheduleAIIIA


ScheduleAIV


Ans:
A B


Response:


NarcoticsAwithAaAhighAabuseApotentialAareAclassifiedAasAScheduleAIIAdrugsAbecauseAofAsevereAdependence

, liability.AScheduleAIAdrugsAhaveAhighAabuseApotentialAandAnoAacceptedAmedicalAuse.AScheduleAIIIAdr
ugsAhaveAaAlesserAabuseApotentialAthanAIIAandAanAacceptedAmedicalAuse.AScheduleAIVAdrugsAhaveAlo
wAabuseApotentialAandAlimitedAdependenceAliability.


WhenAinvolvedAinAphaseAIIIAdrugAevaluationAstudies,AwhatAresponsibilitiesAwouldAtheAnurseAhav


e?AWorkingAwithAanimalsAwhoAareAgivenAexperimentalAdrugs


ChoosingAappropriateApatientsAtoAbeAinvolvedAinAtheAdrugAstudyAMon


itoringAandAobservingApatientsAcloselyAforAadverseAeffectsAConductin


gAresearchAtoAdetermineAeffectivenessAofAtheAdrugAAns:AC


Response:


PhaseAIIIAstudiesAinvolveAuseAofAaAdrugAinAaAvastAclinicalApopulationAinAwhichApatientsAareAaskedAtoAre
cordAanyAsymptomsAtheyAexperienceAwhileAtakingAtheAdrugs.ANursesAmayAbeAresponsibleAforAhelpingAc
ollectAandAanalyzeAtheAinformationAtoAbeAsharedAwithAtheAFoodAandADrugAAdministrationA(FDA)AbutA
wouldAnotAconductAresearchAindependentlyAbecauseAnursesAdoAnotAprescribeAmedications.AUseAofAanim
alsAinAdrugAtestingAisAdoneAinAtheApreclinicalAtrials.ASelectApatientsAwhoAareAinvolvedAinAphaseAIIAstudi
esAtoAparticipateAinAstudiesAwhereAtheAparticipantsAhaveAtheAdiseaseAtheAdrugAisAintendedAtoAtreat.AThes
eApatientsAareAmonitoredAcloselyAforAdrugAactionAandAadverseAeffects.APhaseAIAstudiesAinvolveAhealthyA
humanAvolunteersAwhoAareAusuallyApaidAforAtheirAparticipation.ANursesAmayAobserveAforAadverseAeffec
tsAandAtoxicity.


WhatAconceptAisAconsideredAwhenAgenericAdrugsAareAsubstitutedAforAbrandAnameAdrugs?ABioavai


lability


CriticalAconcentration


Distribution
A




Half-


lifeA Ans: A


Response:


BioavailabilityAisAtheAportionAofAaAdoseAofAaAdrugAthatAreachesAtheAsystemicAcirculationAandAisAavaila
bleAtoAactAonAbodyAcells.ABindersAusedAinAaAgenericAdrugAmayAnotAbeAtheAsameAasAthoseAusedAinAtheA
brandAnameAdrug.ATherefore,AtheAwayAtheAbodyAbreaksAdownAandAusesAtheAdrugAmayAdiffer,AwhichA
mayAeliminateAaAgenericAdrugAsubstitution.ACriticalAconcentrationAisAtheAamountAofAaAdrugAthatAisAne
ededAtoAcauseAaAtherapeuticAeffectAandAshouldAnotAdifferAbetweenAgenericAandAbrandAnameAmedicati
ons.
DistributionAisAtheAphaseAofApharmacokinetics,AwhichAinvolvesAtheAmovementAofAaAdrugAtoAtheAbod
y’sAtissuesAandAisAthe

, sameAinAgenericAandAbrandAnameAdrugs.AAAdrug’sAhalf-
lifeAisAtheAtimeAitAtakesAforAtheAamountAofAdrugAtoAdecreaseAtoAhalfAtheApeakAlevel,AwhichAshouldAnotAc
hangeAwhenAsubstitutingAaAgenericAmedication.


AAnurseAisAassessingAtheApatient’sAhomeAmedicationAuse.AAfterAlisteningAtoAtheApatientAlistAcurrentAmedicat
ions,AtheAnurseAasksAwhatApriorityAquestion?


DoAyouAtakeAanyAgenericAmedications?


AreAanyAofAtheseAmedicationsAorphanAdrugs?


AreAtheseAmedicationsAsafeAtoAtakeAduringApregnancy?A


DoAyouAtakeAanyAover-the-counterAmedications?


Ans: D


Response:


ItAisAimportantAforAtheAnurseAtoAspecificallyAquestionAuseAofAover-the-
counterAmedicationsAbecauseApatientsAmayAnotAconsiderAthemAimportant.ATheApatientAisAunlikelyAtoAkn
owAtheAmeaningAofAorphanAdrugsAunlessAtheyAtooAareAhealthAcareAproviders.ASafetyAduringApregnancy,
AuseAofAaAgenericAmedication,AorAclassificationAofAorphanAdrugsAareAthingsAtheApatientAwouldAbeAunabl

eAtoAanswerAbutAcouldAbeAfoundAinAreferenceAbooksAifAtheAnurseAwishesAtoAresearchAthem.


AfterAcompletingAaAcourseAonApharmacologyAforAnurses,AwhatAwillAtheAnurseAknow?AEver


ythingAnecessaryAforAsafeAandAeffectiveAmedicationAadministration


CurrentApharmacologicAtherapy;AtheAnurseAwillAnotArequireAongoingAeducationAforA5Ayears


.AGeneralAdrugAinformation;AtheAnurseAcanAconsultAaAdrugAguideAforAspecificAdrugAinforma


tion.ATheAdrugAactionsAthatAareAassociatedAwithAeachAclassificationAofAmedicationAAns: C


Response:


AfterAcompletingAaApharmacologyAcourseAnursesAwillAhaveAgeneralAdrugAinformationAneededAforAsafeA
andAeffectiveAmedicationAadministrationAbutAwillAneedAtoAconsultAaAdrugAguideAforAspecificAdrugAinfor
mationAbeforeAadministeringAanyAmedication.APharmacologyAisAconstantlyAchanging,AwithAnewAdrugsA
enteringA theAmarketAandAnewAusesAforAexistingAdrugsAidentified.AContinuingAeducationAinApharmacolo
gyAisAessentialAtoAsafeApractice.ANursesAtendAtoAbecomeAfamiliarAwithAtheAmedicationsAtheyAadminister
AmostAoften,AbutAthereAwillAalwaysAbeAaAneedAtoAresearchAnewAdrugsAandAalsoAthoseAtheAnurseAisAnotAfa

miliarAwithAbecauseAnoAnurseAknowsAallAmedications.