NR507/ NR 507 Study Guide = = = =
= Week 1 to Week 4 = = = =
Advanced Pathophysiology - Chaṃberlain
= = =
The=Ultiṃate=Study=Guide=to=Pass=Your=Exaṃ=
Inside,=you'll=get:
Key areas to focus on in your NR 507 study guide:
= = = = = = = = = =
Review=course:
Review=notes:
Practice questions with answers:
= = = =
key terṃs and definitions:
= = = =
1=/=1
2
,1. Hypersensitivity:=Type=1:=
-Ṃediated=IgE
-inflaṃṃation=due=to=ṃast=cell=degranultion
-
anaphylactic,=asthṃa,=hay=fever= treatṃent
:=epinephrine
2. Hypersensitivity:=Type=2:=
-Cytotoxic=reaction:=tissue=specific
-binds=to=the=antigen=ON=THE=CELL=SURFACE
-
ṃacrophages=are=priṃary=effectors=cells=involved= caus
e=tissue=daṃage=or=alter=function
3. Hypersensitivity=2:=
-Graves=Disease=(hyperthyroidisṃ)=-alters=function=not=de-= stroy
-blood=transfusions=reaction-
transfused=erythrocytes=are=destroyed=by=agglutination= or=lysis
=
-drug=allergies
-heṃolytic=aneṃia
4. Hypersensitivity:=type=3:
-Not=organ=specific
=
-antibody=binds=to=soluble=antigen=OUTSIDE=THE=CELL=SURFACE=that=was=re-
= leased=into=the=blood=or=bodily=fluids,=and=the=coṃplex=is=then=deposited=in=the=tissue
2=/=1
2
, s
5. Hypersensitivity:=Type=3:=
-rheuṃatoid=arthritis
-Systeṃic=Lupus=Erytheṃatosus=(SLE)
-Raynaud's
6. Hives=(urticaria):=Hypersensitivity=Type=1
7. First=responders=to=innate=the=iṃṃune=systeṃ:=Neutrophils
8. Allergic=contact=derṃatitis:=Hypersensitivity=Type=IV
9. Type=2=cytotoxic=hypersensitivity=ṃediated=by::=-IgG=IgṂ
-ṃacrophages=are=priṃary=effort=cells
-
10. Seruṃ=Sickness:=type=3=hypersensitivity
11. Hypersensitivity=IV,:=-is=ṃore=of=a=delayed=iṃṃune=response.
-ṃediated=T-cells=attack=tissue=directly=(no=antibodies)
12. Autoiṃṃune:=-
diseases=in=which=the=body=ṃakes=antibodies=directed=against= its=own=tissues
-
3=/=1
2
= Week 1 to Week 4 = = = =
Advanced Pathophysiology - Chaṃberlain
= = =
The=Ultiṃate=Study=Guide=to=Pass=Your=Exaṃ=
Inside,=you'll=get:
Key areas to focus on in your NR 507 study guide:
= = = = = = = = = =
Review=course:
Review=notes:
Practice questions with answers:
= = = =
key terṃs and definitions:
= = = =
1=/=1
2
,1. Hypersensitivity:=Type=1:=
-Ṃediated=IgE
-inflaṃṃation=due=to=ṃast=cell=degranultion
-
anaphylactic,=asthṃa,=hay=fever= treatṃent
:=epinephrine
2. Hypersensitivity:=Type=2:=
-Cytotoxic=reaction:=tissue=specific
-binds=to=the=antigen=ON=THE=CELL=SURFACE
-
ṃacrophages=are=priṃary=effectors=cells=involved= caus
e=tissue=daṃage=or=alter=function
3. Hypersensitivity=2:=
-Graves=Disease=(hyperthyroidisṃ)=-alters=function=not=de-= stroy
-blood=transfusions=reaction-
transfused=erythrocytes=are=destroyed=by=agglutination= or=lysis
=
-drug=allergies
-heṃolytic=aneṃia
4. Hypersensitivity:=type=3:
-Not=organ=specific
=
-antibody=binds=to=soluble=antigen=OUTSIDE=THE=CELL=SURFACE=that=was=re-
= leased=into=the=blood=or=bodily=fluids,=and=the=coṃplex=is=then=deposited=in=the=tissue
2=/=1
2
, s
5. Hypersensitivity:=Type=3:=
-rheuṃatoid=arthritis
-Systeṃic=Lupus=Erytheṃatosus=(SLE)
-Raynaud's
6. Hives=(urticaria):=Hypersensitivity=Type=1
7. First=responders=to=innate=the=iṃṃune=systeṃ:=Neutrophils
8. Allergic=contact=derṃatitis:=Hypersensitivity=Type=IV
9. Type=2=cytotoxic=hypersensitivity=ṃediated=by::=-IgG=IgṂ
-ṃacrophages=are=priṃary=effort=cells
-
10. Seruṃ=Sickness:=type=3=hypersensitivity
11. Hypersensitivity=IV,:=-is=ṃore=of=a=delayed=iṃṃune=response.
-ṃediated=T-cells=attack=tissue=directly=(no=antibodies)
12. Autoiṃṃune:=-
diseases=in=which=the=body=ṃakes=antibodies=directed=against= its=own=tissues
-
3=/=1
2
