1. A structured approach to prescribing that includes WHO Prescribing Process
making a diagnosis, setting therapeutic goals, decid-
ing on therapeutic approaches, choosing a drug class,
selecting a generic drug, individualizing dose and for-
mulation, verifying drug suitability, writing the pre-
scription, informing the patient, monitoring effects,
and altering the prescription if necessary.
2. Different methods of delivering drugs into the body, Routes of Administration
including oral, rectal, sublingual, intrathecal, trans-
dermal, intravenous (IV), intramuscular (IM), subcuta-
neous (SQ), topical, and inhalation.
3. The study of what the drug does to the body. Pharmacodynamics
4. The study of what the body does to the drug. Pharmacokinetics
5. The process by which a drug enters the bloodstream, Absorption
influenced by routes of administration and factors like
membrane solubility and ionization.
6. The dispersion of a drug throughout the fluids and Distribution
tissues of the body.
7. The process by which the body breaks down and inac- Metabolism
tivates a drug, typically occurring in the liver.
8. The process by which a drug leaves the body, primarily Elimination/Excretion
through urine, feces, sweat, or respiration.
9. The proportion of a drug that enters the circulation Bioavailability
when introduced into the body and is available for
action.
, NURS 615: Advanced Pharmacology Exam 1 Study Guide
10. The ability of a drug to produce the desired therapeu- Efficacy
tic effect.
11. The amount of drug required to achieve a specific Potency
effect.
12. A pharmacological parameter that describes the dis- Volume of Distribution
tribution of a drug throughout the body.
13. Fat-loving drugs that easily cross biological mem- Lipophilic Drugs
branes, have a high volume of distribution, and are
cleared by the liver.
14. Water-loving drugs that do not cross membranes eas- Hydrophilic Drugs
ily, have a low volume of distribution, and are cleared
by the kidneys.
15. The process by which the liver makes a substance Conjugation
water-soluble for elimination.
16. The metabolic process where a drug is broken down in First Pass Metabolism
the gastrointestinal system and liver before entering
systemic circulation, reducing its bioavailability.
17. A group of enzymes, particularly CYPs, that play a Isoenzymes and p450
major role in drug metabolism. System
18. Substances that inhibit the metabolism of enzymes Inhibitors
that metabolize drugs, potentially increasing drug lev-
els in the system.
19. Substances that promote the production of more en- Inducers
zymes, which can decrease the effectiveness of cer-
tain drugs.