ONS CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATE COMPLETE EXAM QUESTIONS
AND SOLUTIONS GRADED A+ 2026
◉ What is unique about nitrosoureas agents? Answer: Able to cross
the blood-brain barrier; can be effective in treating some brain
tumors
◉ Common nitrosoureas agents: Answer: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
◉ Hypersensitivity can occur with late doses of: Answer:
Carboplatin
◉ These agents are typically categorized as highly emetogenic:
Answer: 1. Alkylating agents
2. Nitrosoureas
◉ Pre-administration labs for alkylating agents and nitrosoureas:
Answer: BUN
Creatinine
,CBC w/ diff
◉ What is the medication Mesna used for? Answer: Bladder
protectant with administration of cyclophosphamide or ifosfamide
◉ Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment Answer:
Oxaliplatin
◉ How do antimetabolites function? Answer: By blocking DNA and
RNA growth by interfering with enzymes needed for normal cell
metabolism
◉ Antimetabolites work in the ___ phase. Answer: S
◉ What types of cells are best affected by antimetabolites? Answer:
Cells with high division rates
◉ Common side effects of antimetabolites: Answer:
Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
, ◉ Common antimetabolite drugs: Answer: Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
◉ The institute for Safe Medication Practices recommends what
route of administration for vincristine? Answer: IV piggyback via
gravity
◉ Anthracycline antitumor abx work by: Answer: Interfering with
enzymes necessary for DNA to replicate in ALL phases of the cell
cycle
◉ The two major classifications of antitumor antibiotics are:
Answer: Anthracyclines
Non-anthracyclines
◉ Common anthracycline antitumor abx: Answer: Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
CERTIFICATE COMPLETE EXAM QUESTIONS
AND SOLUTIONS GRADED A+ 2026
◉ What is unique about nitrosoureas agents? Answer: Able to cross
the blood-brain barrier; can be effective in treating some brain
tumors
◉ Common nitrosoureas agents: Answer: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
◉ Hypersensitivity can occur with late doses of: Answer:
Carboplatin
◉ These agents are typically categorized as highly emetogenic:
Answer: 1. Alkylating agents
2. Nitrosoureas
◉ Pre-administration labs for alkylating agents and nitrosoureas:
Answer: BUN
Creatinine
,CBC w/ diff
◉ What is the medication Mesna used for? Answer: Bladder
protectant with administration of cyclophosphamide or ifosfamide
◉ Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment Answer:
Oxaliplatin
◉ How do antimetabolites function? Answer: By blocking DNA and
RNA growth by interfering with enzymes needed for normal cell
metabolism
◉ Antimetabolites work in the ___ phase. Answer: S
◉ What types of cells are best affected by antimetabolites? Answer:
Cells with high division rates
◉ Common side effects of antimetabolites: Answer:
Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
, ◉ Common antimetabolite drugs: Answer: Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
◉ The institute for Safe Medication Practices recommends what
route of administration for vincristine? Answer: IV piggyback via
gravity
◉ Anthracycline antitumor abx work by: Answer: Interfering with
enzymes necessary for DNA to replicate in ALL phases of the cell
cycle
◉ The two major classifications of antitumor antibiotics are:
Answer: Anthracyclines
Non-anthracyclines
◉ Common anthracycline antitumor abx: Answer: Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
