What are arterial thrombi composed of?
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Fibrin and platelets
What factor is deficient in Hemophilia B?
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Factor IX
What is a major clinical problem associated with HIT?
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Thrombosis (arterial and venous)
What is a thrombus composed of?
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Fibrin and blood cells
What are the clinical manifestations of a bleed from a coagulopathy?
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Joint bleeding; tissue hematomas; large, spontaneous, centrally located
What are the most common sites of bleeding in Hemophilia A?
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knees, elbows, and ankles; GI bleeding; spontaneous bleeding indicative of
severe disease; bleeding only after injury/trauma or surgery indicates
milder disease
A platelet count above what is enough to maintain hemostasis?
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50,000
When should you suspect a thrombophilia?
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Recurrent thromboembolism; VTE in person < 40; familial history of venous
thromboembolism; thrombosis in unusual sites as mesenteric vein, renal
vein, hepatic and cerebral thrombosis
What is Type 2 HIT?
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Immune mediated drug reaction resulting in platelet destruction; severe
form of HIT
What are the clinical manifestations of HIT?
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An otherwise unexplained fall in platelet count 5-10 days after receiving
heparin; 25-30% of patients present with rapid onset HIT, in which platelet
count falls abruptly; persons can present with HIT up to 2 weeks after their
last exposure to heparin
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Fibrin and platelets
What factor is deficient in Hemophilia B?
Give this one a try later!
Factor IX
What is a major clinical problem associated with HIT?
,Give this one a try later!
Thrombosis (arterial and venous)
What is a thrombus composed of?
Give this one a try later!
Fibrin and blood cells
What are the clinical manifestations of a bleed from a coagulopathy?
Give this one a try later!
Joint bleeding; tissue hematomas; large, spontaneous, centrally located
What are the most common sites of bleeding in Hemophilia A?
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knees, elbows, and ankles; GI bleeding; spontaneous bleeding indicative of
severe disease; bleeding only after injury/trauma or surgery indicates
milder disease
A platelet count above what is enough to maintain hemostasis?
, Give this one a try later!
50,000
When should you suspect a thrombophilia?
Give this one a try later!
Recurrent thromboembolism; VTE in person < 40; familial history of venous
thromboembolism; thrombosis in unusual sites as mesenteric vein, renal
vein, hepatic and cerebral thrombosis
What is Type 2 HIT?
Give this one a try later!
Immune mediated drug reaction resulting in platelet destruction; severe
form of HIT
What are the clinical manifestations of HIT?
Give this one a try later!
An otherwise unexplained fall in platelet count 5-10 days after receiving
heparin; 25-30% of patients present with rapid onset HIT, in which platelet
count falls abruptly; persons can present with HIT up to 2 weeks after their
last exposure to heparin
