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CANC 380 Module 3 (2026) Questions and
Correct Answers/ Latest Update / Already
Graded
What does TME stand for?
Ans: Tumor Microenvironment
What are the main components of the tumor microenvironment?
Ans: Cellular components, extracellular components (ECM),
and physical parameters (temperature, interstitial pressure, pH,
oxygen level).
How do cancer cells interact with the tumor microenvironment?
Ans: Through continuous communication mediated by
cytokines, chemokines, growth factors, inflammatory
molecules, and matrix-remodelling enzymes.
What role do immune cells play in the TME?
Ans: They can promote or inhibit tumor growth depending on
their interactions with cancer cells.
What is angiogenesis?
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Ans: The formation of new blood vessels from existing ones,
necessary for tumor growth.
What are angiogenic inducers?
Ans: Substances that promote blood vessel growth, such as
VEGF and bFGF.
What are angiogenic inhibitors?
Ans: Substances that prevent unnecessary vessel growth, such
as thrombospondin-1 and angiostatin.
What is lymphangiogenesis?
Ans: The formation of new lymphatic vessels, which is common
in cancer.
What is the significance of pericytes in the TME?
Ans: They provide vessel stability, control permeability, and
regulate endothelial adhesion molecules.
What is the impact of hypoxia on tumors?
All rights reserved © 2025/ 2026 |
CANC 380 Module 3 (2026) Questions and
Correct Answers/ Latest Update / Already
Graded
What does TME stand for?
Ans: Tumor Microenvironment
What are the main components of the tumor microenvironment?
Ans: Cellular components, extracellular components (ECM),
and physical parameters (temperature, interstitial pressure, pH,
oxygen level).
How do cancer cells interact with the tumor microenvironment?
Ans: Through continuous communication mediated by
cytokines, chemokines, growth factors, inflammatory
molecules, and matrix-remodelling enzymes.
What role do immune cells play in the TME?
Ans: They can promote or inhibit tumor growth depending on
their interactions with cancer cells.
What is angiogenesis?
All rights reserved © 2025/ 2026 |
, Page |2
Ans: The formation of new blood vessels from existing ones,
necessary for tumor growth.
What are angiogenic inducers?
Ans: Substances that promote blood vessel growth, such as
VEGF and bFGF.
What are angiogenic inhibitors?
Ans: Substances that prevent unnecessary vessel growth, such
as thrombospondin-1 and angiostatin.
What is lymphangiogenesis?
Ans: The formation of new lymphatic vessels, which is common
in cancer.
What is the significance of pericytes in the TME?
Ans: They provide vessel stability, control permeability, and
regulate endothelial adhesion molecules.
What is the impact of hypoxia on tumors?
All rights reserved © 2025/ 2026 |
