Pharmacodynamics, Drug Metabolism, Medication
Administration Rights, Antibiotic Classes, Antiviral
and Antifungal Agents, Topical Medications, Drug
Interactions, Adverse Drug Reactions, Routes of
Administration, Therapeutic and Toxic Doses, First-
Pass Metabolism, Beta-Lactam Antibiotics,
Fluoroquinolones, Aminoglycosides, Tetracyclines,
Sulfonamides, Corticosteroids, Antiseptics,
Anesthetics – Comprehensive Nursing
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Pharmaceutical Phase
The manufacture of a drug until absorption takes place in the body.
Pharmacokinetic Phase
What the body does with the drug. Absorption, distribution, metabolism, excretion.
Pharmacodynamic Phase
What the drug does to the body.
The Liver
Inactivates and metabolizes drugs. Detoxification.
The Kidneys
Eliminate the byproducts.
Cumulative Affect
Drug build-up in the body.
Therapeutic Dose
, Positive result.
Lethal Dose
Amount of drug that will cause death.
Toxic Dose
Amount of drug that will produce s & s of poisoning.
Drug Interaction
One drug alters another drug.
Antagonist
Drug that will block the action of another drug. Example is narcam for respiratory depression
Reduced Response
Tolerance to a drug. Antihistamines are varied because of this.
Allergic Reaction
Anaphylaxis may occur. Epinephrine used to constrict blood vessels.
Medication Orders Should Include. 1-8
Name
Date and Time
Drug
Dosage
Route
Frequency
Physician Signature
Any Special Instructions
Adverse Drug Reaction
Harmful, unintended reaction to a drug administered at a normal dosage.
Contraindications
Conditions in which drug should not be given
Trade Name
Short, brand name received from manufacturer