Bio 99 Final (Quizzes) Questions With Complete Solutions
Which of the following statements is a feature of the wobble
hypothesis?
When inosine (I) is the first nucleotide of an anticodon, up to
three different codons can be recognized by that tRNA.
Because the genetic code is non-overlapping, a missense
mutation (from a single nucleotide change) results in the
alteration of ___________, and the resulting protein has
_____________.
-1st blank: only one codon
-2nd blank: at most, a single amino acid change
A frameshift of an entire coding region of an mRNA molecule is
most likely to be caused by a:
Single nucleotide deletion.
Which of the following statements about the use of synthetic
polynucleotides in cracking the genetic code is true?
-Poly(A) RNA directs the synthesis of only polylysine in vitro
-The codon table was completed by using RNA polymers of
defined sequences
-Particular codons are generated in predictable ratios with
random RNA polymers containing specific ratios of different
nucleotides
Which of the following best describes the procedure Nirenberg
took to decipher the genetic code?
, They added ribosomes, tRNA, and codons together to see which
codons resulted in tRNA/ribosome association.
Which of the following is true regarding the make-up of the
ribosome?
The RNA make up more of the ribosome mass than the protein
components.
Which one of the following experimental results does not
support the hypothesis that the ribosome is a ribozyme?
Ribosomes from thermophilic organisms are more stable than
from E. coli.
Which of the following best describes the tRNA binding sites of
the ribosome?
The P site contains the tRNA molecule covalently bound to the
growing chain of amino acids.
The changing or activation of a tRNA molecule includes:
the covalent attachment of the carboxyl group of an amino acid
to the tRNA.
A difference between a Class I and a Class II tRNA synthetase is
(select all that apply):
-the Class I synthetase uses the 2' OH of the 3' end of the tRNA
as a nucleophile and the Class II uses the 3' OH.
-the Class I synthetase reaction requires a transesterification
reaction not necessary in the Class II reaction.
What result allowed Dintzis to conclude that proteins are
synthesized from the N terminus to C terminus?
Which of the following statements is a feature of the wobble
hypothesis?
When inosine (I) is the first nucleotide of an anticodon, up to
three different codons can be recognized by that tRNA.
Because the genetic code is non-overlapping, a missense
mutation (from a single nucleotide change) results in the
alteration of ___________, and the resulting protein has
_____________.
-1st blank: only one codon
-2nd blank: at most, a single amino acid change
A frameshift of an entire coding region of an mRNA molecule is
most likely to be caused by a:
Single nucleotide deletion.
Which of the following statements about the use of synthetic
polynucleotides in cracking the genetic code is true?
-Poly(A) RNA directs the synthesis of only polylysine in vitro
-The codon table was completed by using RNA polymers of
defined sequences
-Particular codons are generated in predictable ratios with
random RNA polymers containing specific ratios of different
nucleotides
Which of the following best describes the procedure Nirenberg
took to decipher the genetic code?
, They added ribosomes, tRNA, and codons together to see which
codons resulted in tRNA/ribosome association.
Which of the following is true regarding the make-up of the
ribosome?
The RNA make up more of the ribosome mass than the protein
components.
Which one of the following experimental results does not
support the hypothesis that the ribosome is a ribozyme?
Ribosomes from thermophilic organisms are more stable than
from E. coli.
Which of the following best describes the tRNA binding sites of
the ribosome?
The P site contains the tRNA molecule covalently bound to the
growing chain of amino acids.
The changing or activation of a tRNA molecule includes:
the covalent attachment of the carboxyl group of an amino acid
to the tRNA.
A difference between a Class I and a Class II tRNA synthetase is
(select all that apply):
-the Class I synthetase uses the 2' OH of the 3' end of the tRNA
as a nucleophile and the Class II uses the 3' OH.
-the Class I synthetase reaction requires a transesterification
reaction not necessary in the Class II reaction.
What result allowed Dintzis to conclude that proteins are
synthesized from the N terminus to C terminus?
