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Peak -CORRECTANSWER Highest concentration of the drug
Trough -CORRECTANSWER The lowest plasma concentration of a drug and it
measures the rate at which the drug is eliminated
Onset -CORRECTANSWER The time it takes for a drug to reach the minimum effective
concentration
Duration -CORRECTANSWER The length of time the drug exerts therapeutic effects
Agonist -CORRECTANSWER Produces a desired response
Antagonist -CORRECTANSWER Block a desired response
Additive -CORRECTANSWER The sum of the effects of the two drugs
Synergistic effect -CORRECTANSWER When 2 or more drugs are given together, one
drug can have a clinical effect substantially greater than that of either drug alone
, Half Life -CORRECTANSWER The time it takes for the amount of the drug in the body
to be replaced by half
Potentiation -CORRECTANSWER When the combined effects of two different drugs
exceed the expected additive effect of each of the drugs
Pharmacokinetics -CORRECTANSWER Process of drug movement through the body
to achieve necessary drug reaction
Protein Binding -CORRECTANSWER When 2 highly protein drugs are administered
they compete for protein binding sites leading to an increase in free drug being released
into the circulation
Distribution -CORRECTANSWER The movement of the drug from the circulation to
body tissues where it is being absorbed in the body
Bioavailability -CORRECTANSWER Refers to the % of the administered drug available
for activity
Drug Excretion -CORRECTANSWER Elimination of the drug from the body through the
kidneys, bile, lungs, saliva, sweat, and breast milk