Bio 99 Midterm Review Week 3 Questions With Complete
Solutions
A mutant protein has been designated as G189A. What does this
designation reveal about the mutation? Correct Answers That a
glycine in position 189 of the protein is now an Alanine.
Compounds that kill the cell are said to be: Correct Answers
Cytotoxic.
Each replication fork requires both leading and lagging strand
because: Correct Answers The DNA templates are antiparallel
and yet the DNA polymerases only work in one direction.
How did Meselson and Stahl distinguish between
semiconservative and conservative replication in their
experiment? Correct Answers After one round of replication,
only mixed DNA molecules were present in the gradient.
How did Meselson and Stahl distinguish between
semiconservative and dispersive replication in their experiment?
Correct Answers After one round of replication, both heavy and
light DNA single strands were present in alkaline gradients.
Insetions and deletions of three base pairs: Correct Answers Do
not disrupt the reading frame so the protein witlll usually retain
some degree of function.
Observing replication of circular plasmid DNAs by electron
microscopy showed that: Correct Answers Replication initiates
, from a single origin, creating a single replication bubble in the
plasmid.
Polyglutamine (polyQ) diseases: Correct Answers Result from
template slippage during replication.
Result when CAG repeats increase above the disease threshold.
Is a triple expansion diseases.
Include hunington disease and fragile X syndrome.
The E. Coli origin, oriC, contains: Correct Answers Four 9-
base-pair consensus sequences, three AT-rich direct repeats, and
eleven GTAC sites.
The exchange of purine-pyrimidine base pair for the other
purine-pyrimidine pair is a ________ mutation. Correct Answers
Transition
The function of DNA ligase is to: Correct Answers Catalyze the
formation of covalent bonds between adjacent nucleotides.
Watson and Crick proposed that during DNA replication the
double wound and each parental DNA strand is used as a
template to generate a new daughter strand. What is this mode of
replication called? Correct Answers Semiconservative
replication
What bases are most susceptible to hydrolysis of the glycosidic
linkage that connects them to the DNA backbone? Correct
Answers Adenine and Guanine
Solutions
A mutant protein has been designated as G189A. What does this
designation reveal about the mutation? Correct Answers That a
glycine in position 189 of the protein is now an Alanine.
Compounds that kill the cell are said to be: Correct Answers
Cytotoxic.
Each replication fork requires both leading and lagging strand
because: Correct Answers The DNA templates are antiparallel
and yet the DNA polymerases only work in one direction.
How did Meselson and Stahl distinguish between
semiconservative and conservative replication in their
experiment? Correct Answers After one round of replication,
only mixed DNA molecules were present in the gradient.
How did Meselson and Stahl distinguish between
semiconservative and dispersive replication in their experiment?
Correct Answers After one round of replication, both heavy and
light DNA single strands were present in alkaline gradients.
Insetions and deletions of three base pairs: Correct Answers Do
not disrupt the reading frame so the protein witlll usually retain
some degree of function.
Observing replication of circular plasmid DNAs by electron
microscopy showed that: Correct Answers Replication initiates
, from a single origin, creating a single replication bubble in the
plasmid.
Polyglutamine (polyQ) diseases: Correct Answers Result from
template slippage during replication.
Result when CAG repeats increase above the disease threshold.
Is a triple expansion diseases.
Include hunington disease and fragile X syndrome.
The E. Coli origin, oriC, contains: Correct Answers Four 9-
base-pair consensus sequences, three AT-rich direct repeats, and
eleven GTAC sites.
The exchange of purine-pyrimidine base pair for the other
purine-pyrimidine pair is a ________ mutation. Correct Answers
Transition
The function of DNA ligase is to: Correct Answers Catalyze the
formation of covalent bonds between adjacent nucleotides.
Watson and Crick proposed that during DNA replication the
double wound and each parental DNA strand is used as a
template to generate a new daughter strand. What is this mode of
replication called? Correct Answers Semiconservative
replication
What bases are most susceptible to hydrolysis of the glycosidic
linkage that connects them to the DNA backbone? Correct
Answers Adenine and Guanine
