Intro Medical-Surgical Nursing by Timby & Smith: Ch 31 Caring for Clients w/ Disorders of the Hematopoietic System: Red Blood Cell Morphology (Normocytic, Microcytic, Macrocytic, Megaloblastic), Hemoglobin Concentration Variations (Normochromic, Hypochrom

Intro Medical-Surgical Nursing by Timby & Smith: Ch 31 Caring for Clients w/ Disorders of the Hematopoietic System: Red Blood Cell Morphology (Normocytic, Microcytic, Macrocytic, Megaloblastic), Hemoglobin Concentration Variations (Normochromic, Hypochromic, Hyperchromic), Anemia Classification (Hypovolemic, Iron Deficiency, Pernicious, Folic Acid Deficiency, Aplastic, Hemolytic), Hemoglobinopathies (Sickle Cell Disease, Thalassemias), Hematologic Malignancies (Leukemia Subtypes and Multiple Myeloma), Platelet and Coagulation Disorders (Thrombocytopenia, Purpura, Hemophilia A/B/C, von Willebrand Disease), Bone Marrow Suppression Syndromes, Clinical Manifestations, Pathophysiology, and Therapeutic Interventions Including Chelation Therapy Exam Questions Verified and Provided with A+ Graded Rationales Latest Updated 2026 Blood dyscrasia abnormal or pathologic condition of the blood Anemia deficient in either erythrocytes or hemoglobin Normocytic normal cell size Microcytic small cell size Macrocytic large cell size Megaloblastic large immature cell Normochromic normal hemoglobin concentration Hypochromic low hemoglobin concentration Hyperchromic high hemoglobin concentration Aplastic decreased cell production Hemolytic premature destruction Pernicious potentially injurious heme pigmented, iron-containing portion of hemoglobin Hypovolemic Anemia anemia caused by a loss of blood volume, which results in fewer blood cells iron deficiency anemia anemia that develops with iron is insufficient to produce hemoglobin sickle cell disease type of anemia in which erythrocytes become crescent shaped with oxygen supply in the blood is inadequate fetal hemoglobin (HbF) present during intrauterine development through 6 months of age hemoglobin A normal form of hemoglobin, eventually replaces HbF hemoglobin S an abnormal form of hemoglobin when under hypoxic conditions, HbS causes RBC's to assume a sickled shape hemoglobin polymerization the formation of crystal-like rods that change the biconcave RBC into an irregular, brittle, sticky, sickle-shaped cell acute chest syndrome type of pneumonia triggered by decreased hemoglobin and infiltrates in the lungs hemolytic anemia reduction in red cells due to excessive destruction thalassemias hereditary hemolytic anemias chelation therapy process in which heavy metals such as iron are pharmacologically removed from the blood to prevent organ damage and death pernicious anemia develops when a client lacks the intrinsic factor, which is necessary for absorption of vitamin B12 folic acid-deficiency anemia immature erythrocytes erythrocytosis an increase in circulating erythrocytes polycythemia vera characterized by a greater-than-normal number of erythrocytes, leukocytes, and platelets leukemia refers to any malignant blood disorder in which proliferation of leukocytes, usually in an immature form, is unregulated Type: Acute lymphocytic leukemia (ALL) Age of onset: younger than 5 yrs; uncommon after 15 yrs Type: Chronic lymphocytic leukemia (CLL) Age