NR546-Finalexam-Pearls Carefully Structured
Questions With Correct Verified Solutions
Already Graded A+ 2026
First line treatment for depression ANSWER >> SSRIs
1
,Common side effect of SSRIs ANSWER >> sexual dysfunction
rapid cycling bipolar disorder ANSWER >> Minimum of 4 episodes a year
Goal of antidepressant therapy ANSWER >> complete remission of symptoms
Serotonin GI effects ANSWER >> Due to the fact that 90% of 5HT receptors are located
in GI tract
best tolerated SSRI ANSWER >> Escitalopram (Lexapro) also has fewest CYP
interactions
Lithium levels ANSWER >> Can be increased by NSAIDS and ACE inhibitors
Can be decreased by caffeine and mania
Unaffected by amiloride, furosemide, and sulindac
Lithium purpose ANSWER >> Effective treatment for manic episodes, to prevent
reoccurrence and to a lower degree is effective in depressive episodes
Lamotrigine ANSWER >> Well tolerated except for the propensity to cause a rash
Monoamines ANSWER >> dopamine, norepinephrine, serotonin
Lamotrigine ANSWER >> Is a mood stabilizer
Lithium ANSWER >> Well established to prevent suicide in clients with mood disorders
Lithium ANSWER >> Has a narrow therapeutic window and requires law draws
2
, 1st line treatment for OCD ANSWER >> SSRIs are first line. Benzodiazepines are not!!!
Primary action of hallucinogenic drugs such as LSD,mescaline, psilocybin, and MDMA
ANSWER >> Agonism of 5HT2A receptors
Hallucinogens may have additional actions at other serotonin receptors (particularly
5HT1A and 5HT2C) and at other neurotransmitter systems, and MDMA in particular
also blocks the serotonin transporter (SERT)
Controls appetite ANSWER >> hypothalamus serves as the brain center that controls
appetite by utilizing a complex set of circuits and regulators. One formulation of how the
hypothalamus does this is the notion that there is a major appetite stimulating pathway
whose actions are mediated by two peptides (neuropeptide Y and agouti-related
protein)
Phentermine ANSWER >> Acts like amphetamine, blocking both the dopamine
transporter (DAT) and the norepinephrine transporter (NET) and, at high doses, the
vesicular monoamine transporter (VMAT)
Buprenorphine ANSWER >> Is also approved for <18 year olds
Disulfiram caution ANSWER >> Alcohol reaction may occur within two weeks of alcohol
ingestion
Methadone ANSWER >> Is a full mu-receptor agonist with a long half-life, which can
prevent withdrawal symptoms for 24 hours and provide steady control of cravings
throughout the day. In addition to its opioid receptor activity, it is also an antagonist of
the N-methyl-D-aspartate (NMDA) receptor.
Hallucinogenic intoxication ANSWER >> pupillary dilation, tachycardia, sweating,
palpitations, blurred vision, tremors, incoordination
Can be perceived as a panic attack and often called a bad trip.
3
Questions With Correct Verified Solutions
Already Graded A+ 2026
First line treatment for depression ANSWER >> SSRIs
1
,Common side effect of SSRIs ANSWER >> sexual dysfunction
rapid cycling bipolar disorder ANSWER >> Minimum of 4 episodes a year
Goal of antidepressant therapy ANSWER >> complete remission of symptoms
Serotonin GI effects ANSWER >> Due to the fact that 90% of 5HT receptors are located
in GI tract
best tolerated SSRI ANSWER >> Escitalopram (Lexapro) also has fewest CYP
interactions
Lithium levels ANSWER >> Can be increased by NSAIDS and ACE inhibitors
Can be decreased by caffeine and mania
Unaffected by amiloride, furosemide, and sulindac
Lithium purpose ANSWER >> Effective treatment for manic episodes, to prevent
reoccurrence and to a lower degree is effective in depressive episodes
Lamotrigine ANSWER >> Well tolerated except for the propensity to cause a rash
Monoamines ANSWER >> dopamine, norepinephrine, serotonin
Lamotrigine ANSWER >> Is a mood stabilizer
Lithium ANSWER >> Well established to prevent suicide in clients with mood disorders
Lithium ANSWER >> Has a narrow therapeutic window and requires law draws
2
, 1st line treatment for OCD ANSWER >> SSRIs are first line. Benzodiazepines are not!!!
Primary action of hallucinogenic drugs such as LSD,mescaline, psilocybin, and MDMA
ANSWER >> Agonism of 5HT2A receptors
Hallucinogens may have additional actions at other serotonin receptors (particularly
5HT1A and 5HT2C) and at other neurotransmitter systems, and MDMA in particular
also blocks the serotonin transporter (SERT)
Controls appetite ANSWER >> hypothalamus serves as the brain center that controls
appetite by utilizing a complex set of circuits and regulators. One formulation of how the
hypothalamus does this is the notion that there is a major appetite stimulating pathway
whose actions are mediated by two peptides (neuropeptide Y and agouti-related
protein)
Phentermine ANSWER >> Acts like amphetamine, blocking both the dopamine
transporter (DAT) and the norepinephrine transporter (NET) and, at high doses, the
vesicular monoamine transporter (VMAT)
Buprenorphine ANSWER >> Is also approved for <18 year olds
Disulfiram caution ANSWER >> Alcohol reaction may occur within two weeks of alcohol
ingestion
Methadone ANSWER >> Is a full mu-receptor agonist with a long half-life, which can
prevent withdrawal symptoms for 24 hours and provide steady control of cravings
throughout the day. In addition to its opioid receptor activity, it is also an antagonist of
the N-methyl-D-aspartate (NMDA) receptor.
Hallucinogenic intoxication ANSWER >> pupillary dilation, tachycardia, sweating,
palpitations, blurred vision, tremors, incoordination
Can be perceived as a panic attack and often called a bad trip.
3
