NUR 631 Advanced Physiology and Pathophysiology
Final Exam Prep Test Bank 2 with 200 Exam
Questions and Correct Answers with Rationales/ GCU
NUR 631 Latest Final Exam Prep Test Bank 2026-
2027 (New!)
Which disorders are considered autoimmune?
(Select all that apply.)
a. Crohn disease
b. Addison disease
c. Rheumatoid arthritis
d. Systemic lupus erythematosus
e. Noninsulin-dependent diabetes - ANSWER-a.
b.
c.
d.
Exp: Crohn disease, Addison disease, rheumatoid arthritis, and systemic lupus
erythematosus are all diseases that result from autoimmune pathologic conditions.
Insulin-dependent diabetes is also an autoimmune disorder, but noninsulin-
dependent diabetes is not. page 264-265 Table 9-2
What is the major virus involved in the development of cervical cancer?
,a. Herpes simple virus type 6
b. Herpes simple virus type 2
c. Human papillomavirus
d. Human immunodeficiency virus - ANSWER-c. Human papillomavirus
Exp: Infection with specific subtypes of human papillomavirus HPV cause
virtually all cervical cancers. The remaining options are not known to be associated
with cervical cancer. page 382-383
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
a. IgE
c. IgG
b. IgM
d. T cells - ANSWER-a. IgE
Exp: Type I reactions are mediated by antigen-specific IgE and the products of
tissue mast cells (see figure 9-1). The most common allergies (e.g., pollen
allergies) are type I reactions. In addition, most type I reactions occur against
environmental antigens and are therefore allergic. The other options do not
accurately identify the mediation factor related to hay fever. page 263
Which type of antibody is involved in type I hypersensitivity reaction?
a. IgA
c. IgE
b. IgG
,d. IgM - ANSWER-c. IgE
Exp: Type I reactions are only mediated by antigen-specific IgE and the products
of tissue mast cells (see figure 9-1). page 263
Which statements are true concerning the humoral immune response? (Select all
that apply.)
a. The humoral immune response is divided into major and minor phases.
b. The response has IgG and IgM produced during each of its phrases.
c. It has a greater presence of IgG than IgM in one of its phases.
d. The humoral immune response is produced in reaction to the presence of an
antigen.
e. Phases differ in their response time as a result of the effect of memory cells. -
ANSWER-b. The response has IgG and IgM produced during each of its phrases.
c. It has a greater presence of IgG than IgM in one of its phases.
d. The humoral immune response is produced in reaction to the presence of an
antigen.
e. Phases differ in their response time as a result of the effect of memory cells.
Exp: The humoral immune response is divided into two phases, primary and
secondary. These phases differ in the relative amounts of IgG produced-the
secondary response having a significantly higher proportion of IgG relative to IgM.
The two phases also differ in the speed with which each occurs after the antigen
challenge-the secondary phases is significantly more rapid than the primary phase
because of the presence of memory cells in the secondary phase. page 247
Antibodies that are associated with mucosal immune system, such as
immunoglobulins, function to prevent which type of infections?
, a. Infections that attack the respiratory system
b. Infections that tend to be chronic in nature
c. Infections likely to be resistant to antibiotics
d. Infections that focus on epithelial surfaces of the body - ANSWER-d. Infections
that focus on epithelial surfaces of the body
Exp: Antibodies of the systemic immune system function throughout the body,
whereas antibodies of the secretory (mucosal) immune system-primarily
immunoglobulins of the IgA class-are associated with bodily secretions and
function to prevent pathogenic infection on epithelial surfaces. The other options
are not necessarily true when considering the immunoglobulins. page 252-253
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due
to:
a. Immune complexes that are deposited in capillary beds, blocking circulation
b. Mast cells that are bound to specific endothelial receptors, causing them to
degranulate and creating a localized inflammatory reaction that occludes capillary
circulation
c. Cytotoxic T cells that attack and destroy the capillaries so that the" are unable to
perfuse local tissues
d. Antibodies that detect the capillaries as foreign protein and destroy them using
lysosomal enzymes and toxic oxygen species - ANSWER-a. Immune complexes
that are deposited in capillary beds, blocking circulation
Exp: Raynaud phenomenon is a condition caused by the temperature-dependent
deposition of immune complexes in the capillary beds of the peripheral circulation.
None of the other options are involved in causing this condition. page 270
Final Exam Prep Test Bank 2 with 200 Exam
Questions and Correct Answers with Rationales/ GCU
NUR 631 Latest Final Exam Prep Test Bank 2026-
2027 (New!)
Which disorders are considered autoimmune?
(Select all that apply.)
a. Crohn disease
b. Addison disease
c. Rheumatoid arthritis
d. Systemic lupus erythematosus
e. Noninsulin-dependent diabetes - ANSWER-a.
b.
c.
d.
Exp: Crohn disease, Addison disease, rheumatoid arthritis, and systemic lupus
erythematosus are all diseases that result from autoimmune pathologic conditions.
Insulin-dependent diabetes is also an autoimmune disorder, but noninsulin-
dependent diabetes is not. page 264-265 Table 9-2
What is the major virus involved in the development of cervical cancer?
,a. Herpes simple virus type 6
b. Herpes simple virus type 2
c. Human papillomavirus
d. Human immunodeficiency virus - ANSWER-c. Human papillomavirus
Exp: Infection with specific subtypes of human papillomavirus HPV cause
virtually all cervical cancers. The remaining options are not known to be associated
with cervical cancer. page 382-383
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
a. IgE
c. IgG
b. IgM
d. T cells - ANSWER-a. IgE
Exp: Type I reactions are mediated by antigen-specific IgE and the products of
tissue mast cells (see figure 9-1). The most common allergies (e.g., pollen
allergies) are type I reactions. In addition, most type I reactions occur against
environmental antigens and are therefore allergic. The other options do not
accurately identify the mediation factor related to hay fever. page 263
Which type of antibody is involved in type I hypersensitivity reaction?
a. IgA
c. IgE
b. IgG
,d. IgM - ANSWER-c. IgE
Exp: Type I reactions are only mediated by antigen-specific IgE and the products
of tissue mast cells (see figure 9-1). page 263
Which statements are true concerning the humoral immune response? (Select all
that apply.)
a. The humoral immune response is divided into major and minor phases.
b. The response has IgG and IgM produced during each of its phrases.
c. It has a greater presence of IgG than IgM in one of its phases.
d. The humoral immune response is produced in reaction to the presence of an
antigen.
e. Phases differ in their response time as a result of the effect of memory cells. -
ANSWER-b. The response has IgG and IgM produced during each of its phrases.
c. It has a greater presence of IgG than IgM in one of its phases.
d. The humoral immune response is produced in reaction to the presence of an
antigen.
e. Phases differ in their response time as a result of the effect of memory cells.
Exp: The humoral immune response is divided into two phases, primary and
secondary. These phases differ in the relative amounts of IgG produced-the
secondary response having a significantly higher proportion of IgG relative to IgM.
The two phases also differ in the speed with which each occurs after the antigen
challenge-the secondary phases is significantly more rapid than the primary phase
because of the presence of memory cells in the secondary phase. page 247
Antibodies that are associated with mucosal immune system, such as
immunoglobulins, function to prevent which type of infections?
, a. Infections that attack the respiratory system
b. Infections that tend to be chronic in nature
c. Infections likely to be resistant to antibiotics
d. Infections that focus on epithelial surfaces of the body - ANSWER-d. Infections
that focus on epithelial surfaces of the body
Exp: Antibodies of the systemic immune system function throughout the body,
whereas antibodies of the secretory (mucosal) immune system-primarily
immunoglobulins of the IgA class-are associated with bodily secretions and
function to prevent pathogenic infection on epithelial surfaces. The other options
are not necessarily true when considering the immunoglobulins. page 252-253
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due
to:
a. Immune complexes that are deposited in capillary beds, blocking circulation
b. Mast cells that are bound to specific endothelial receptors, causing them to
degranulate and creating a localized inflammatory reaction that occludes capillary
circulation
c. Cytotoxic T cells that attack and destroy the capillaries so that the" are unable to
perfuse local tissues
d. Antibodies that detect the capillaries as foreign protein and destroy them using
lysosomal enzymes and toxic oxygen species - ANSWER-a. Immune complexes
that are deposited in capillary beds, blocking circulation
Exp: Raynaud phenomenon is a condition caused by the temperature-dependent
deposition of immune complexes in the capillary beds of the peripheral circulation.
None of the other options are involved in causing this condition. page 270
