UPDATE | 100% CORRECT
Endings of benign and cancerous growths Answer - -oma=benign growth
-cacinoma=malignant growth
-sarcoma/myoma=malignant growth of muscle
-Carcinoma in Situ=early or pre-invasive carcinoma of the glandular or
squamous epithelia tissue
what is myleocytic, lymphocytic, multiple myeloma Answer - -
myleocytic=excessive production of granulocytes
-lymphocytic=excessive production of lymphocytes
-multiple myeloma=excessive production of plasma cells
What is paraneoplastic syndrome? Answer - Consequence of the presence of
cancer in the body, but is not due to the local presence of cancer cells or direct
invasion, obstruction, or metastasis of cancer. Mediated by humoral factors
excreted by tumor cells or an immune response against the tumor.
What is the most common gynecologic malignancy? Expand Answer - -
Epithelial ovarian cancer
-increases with age
-Presence of BRCA1 and BRCA2 mutations
-Early menarche is a risk factors
, -Risk decreased by pregnancy, use of contraceptive, breast feeding > 1 year,
hysterectomy, salpingo-oophorectomy
-80% have CA125 marker
-only dx by surgical exploration
-bilateral salpingo-oophorectomy at 35y.o. or after bearing children; decreases
risk by 90%
What is the most common gynecologic malignancies in developed countries?
Answer - -adenocarcinoma of the endometrium
-avg age 61
-Lynch syndrome increases the risk of developing
-most common symptom is vaginal bleeding in theist menopausal woman
-gold standard for eval is pelvic US
-treatment is hysterectomy
multiple myeloma Answer - -malignant proliferation of plasma cells in the
bone marrow
-cause osteolytic lesions, osteopenia, and pathologic fractures
--Occurs more in African American, less risk in Asians from Japan and Mexicans
-More in men than woman
-occurs typically between 50-70 y.o.
-symptom is bone pain (vertebrae is most common)
-increased serum protein, , hypercalcemia, AKI
-and negative protein on the urine dipstick (large, waxy, laminated casts),
SPEP/UPEP 24 hour unrine positive for monodonal (M) protein in 97% of
patients