NUR 651 Final Study Guide questions with verified detailed
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answers
Clinical judgement in prescribing includes: - ✔✔Factoring in the cost to the patient of
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the medication prescribed
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The route of excretion of a volatile drug will likely be the: - ✔✔lungs
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The NP chooses to give cephalexin every 8 hours based on knowledge of the drugs: -
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✔✔biological half-life ||
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
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1. When the drug has a wide therapeutic range
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2. When the drug will be administered for a short time only
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3. When there is a high correlation between the dose and saturation of receptor sites
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4. To determine if a drug is in the therapeutic range - ✔✔To determine if the drug is
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in the therapeutic range
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Drugs that use CYP 3A4 isoenzymes for metabolism may:
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1. Induce the metabolism of another drug
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2. Inhibit the metabolism of another drug
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3. Both 1 and 2
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,4. Neither 1 nor 2 - ✔✔Both 1 & 2: induce OR inhibit metabolism of another drug
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The prudent NP would prescribe liquid ibuprofen for a 6-year-old because: - ✔✔The
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6-year-old may not be able to swallow pills || || || || || || ||
In deciding which drug to prescribe of all multiple drugs used to treat a condition, the
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NP chooses drug A because: - ✔✔It will be taken twice daily at home
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Your patient asks the difference in drug effects between men and women. What should
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the NP know about the differences between pharmacokinetics of men and women? -
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✔✔Percentage of fat differs between genders || || || || ||
Drugs that have a significant first-pass effect: - ✔✔Are rapidly metabolized by the liver
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and may have little if any desired action
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Azithromycin dosing requires the first days dosage be twice those of the other 4 days
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of the prescription. This is considered a loading dose. Loading doses: - ✔✔Rapidly
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achieve drug levels in the theraputic range
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The point in time on the drug concentration curve that indicates the first sign of a
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therapeutic effect is the: - ✔✔onset of action || || || || || || ||
Drugs that are receptor agonists may demonstrate what property? - ✔✔Describes the
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extent of effect (response) produced by a given drug concentration (dose)
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Shows the relationship between the dosage/concentration and the effect of the drug
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concentration
Therapeutic window (range) - ✔✔The range of plasma drug concentration with high
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probability of therapeutic response || || || ||
, Provides a fixed comparison for drug safety
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What is a narrow therapeutic window? - ✔✔A drug that has little difference between
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therapeutic and toxic doses || || ||
Treatment goals in prescribing should be: - ✔✔Patient centered
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storage reservoirs: - ✔✔Fat and tissue that the drug has been distributed to
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Passive monitoring: - ✔✔patient is educated on expected outcome and instructed to
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contact provider (expected side effects)
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A potentially life-threatening adverse response to ACE inhibitors is angioedema.
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Which statement is true about this adverse response? - ✔✔Swelling of the tongue and
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hoarseness are the most common sympotms. || || || || ||
ACE inhibitors are the drug of choice in treating hypertension in diabetic patients
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because: - ✔✔They improve insulin sensitivity
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Improve renal hemodynamics || ||
Reduce the production of angiotensin II
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Ray has been diagnosed with hypertension and an ACE inhibitor is determined to be
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needed. Prior to prescribing this drug, the NP should assess for:
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A. Hypokalemia
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B. Impotence
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C. Decreased renal function
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answers
Clinical judgement in prescribing includes: - ✔✔Factoring in the cost to the patient of
|| || || || || || || || || || || || || ||
the medication prescribed
|| ||
The route of excretion of a volatile drug will likely be the: - ✔✔lungs
|| || || || || || || || || || || || ||
The NP chooses to give cephalexin every 8 hours based on knowledge of the drugs: -
|| || || || || || || || || || || || || || || ||
✔✔biological half-life ||
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
|| || || || || || || || || || || || ||
1. When the drug has a wide therapeutic range
|| || || || || || || ||
2. When the drug will be administered for a short time only
|| || || || || || || || || || ||
3. When there is a high correlation between the dose and saturation of receptor sites
|| || || || || || || || || || || || || ||
4. To determine if a drug is in the therapeutic range - ✔✔To determine if the drug is
|| || || || || || || || || || || || || || || || || ||
in the therapeutic range
|| || ||
Drugs that use CYP 3A4 isoenzymes for metabolism may:
|| || || || || || || ||
1. Induce the metabolism of another drug
|| || || || || ||
2. Inhibit the metabolism of another drug
|| || || || || ||
3. Both 1 and 2
|| || || ||
,4. Neither 1 nor 2 - ✔✔Both 1 & 2: induce OR inhibit metabolism of another drug
|| || || || || || || || || || || || || || || ||
The prudent NP would prescribe liquid ibuprofen for a 6-year-old because: - ✔✔The
|| || || || || || || || || || || || ||
6-year-old may not be able to swallow pills || || || || || || ||
In deciding which drug to prescribe of all multiple drugs used to treat a condition, the
|| || || || || || || || || || || || || || || ||
NP chooses drug A because: - ✔✔It will be taken twice daily at home
|| || || || || || || || || || || || ||
Your patient asks the difference in drug effects between men and women. What should
|| || || || || || || || || || || || ||
the NP know about the differences between pharmacokinetics of men and women? -
|| || || || || || || || || || || || || ||
✔✔Percentage of fat differs between genders || || || || ||
Drugs that have a significant first-pass effect: - ✔✔Are rapidly metabolized by the liver
|| || || || || || || || || || || || ||
and may have little if any desired action
|| || || || || || || ||
Azithromycin dosing requires the first days dosage be twice those of the other 4 days
|| || || || || || || || || || || || || || ||
of the prescription. This is considered a loading dose. Loading doses: - ✔✔Rapidly
|| || || || || || || || || || || || ||
achieve drug levels in the theraputic range
|| || || || || ||
The point in time on the drug concentration curve that indicates the first sign of a
|| || || || || || || || || || || || || || || ||
therapeutic effect is the: - ✔✔onset of action || || || || || || ||
Drugs that are receptor agonists may demonstrate what property? - ✔✔Describes the
|| || || || || || || || || || || ||
extent of effect (response) produced by a given drug concentration (dose)
|| || || || || || || || || ||
Shows the relationship between the dosage/concentration and the effect of the drug
|| || || || || || || || || || || ||
concentration
Therapeutic window (range) - ✔✔The range of plasma drug concentration with high
|| || || || || || || || || || || ||
probability of therapeutic response || || || ||
, Provides a fixed comparison for drug safety
|| || || || || ||
What is a narrow therapeutic window? - ✔✔A drug that has little difference between
|| || || || || || || || || || || || || ||
therapeutic and toxic doses || || ||
Treatment goals in prescribing should be: - ✔✔Patient centered
|| || || || || || || ||
storage reservoirs: - ✔✔Fat and tissue that the drug has been distributed to
|| || || || || || || || || || || ||
Passive monitoring: - ✔✔patient is educated on expected outcome and instructed to
|| || || || || || || || || || || ||
contact provider (expected side effects)
|| || || ||
A potentially life-threatening adverse response to ACE inhibitors is angioedema.
|| || || || || || || || || ||
Which statement is true about this adverse response? - ✔✔Swelling of the tongue and
|| || || || || || || || || || || || || ||
hoarseness are the most common sympotms. || || || || ||
ACE inhibitors are the drug of choice in treating hypertension in diabetic patients
|| || || || || || || || || || || || ||
because: - ✔✔They improve insulin sensitivity
|| || || || ||
Improve renal hemodynamics || ||
Reduce the production of angiotensin II
|| || || || ||
Ray has been diagnosed with hypertension and an ACE inhibitor is determined to be
|| || || || || || || || || || || || || ||
needed. Prior to prescribing this drug, the NP should assess for:
|| || || || || || || || || ||
A. Hypokalemia
||
B. Impotence
||
C. Decreased renal function
|| || ||
