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what are the 3 categories of cancer treatment? Ans✓✓✓localized:
affects tumour cells and surrounding areas
systemic: travels through blood
targeted: block progression by interfering with specific molecules
localized therapies (6) Ans✓✓✓surgery
external beam radiation
brachytherapy
photodynamic therapy
laser focal therapy
high-intensity ultrasound therapy
surgery use Ans✓✓✓remove, diagnose, and stage cancer, relieve
symptoms
first form of therapy, can be combined with others
preventative/prophylactic surgery Ans✓✓✓prevents/lowers risk of
developing certain cancers
e.g. double mastectomy
external beam radiation Ans✓✓✓damages cancer cell DNA
,can use X rays, gammarays, or electron, proton, and neutron particles
what areas of the body external beam radiation Ans✓✓✓larger areas of
the body or multiple areas (tumour and nearby lymph nodes)
brachytherapy Ans✓✓✓radioactive isotope is placed directly into or
close to the tumour, or the area where it was removed
often used for prostate
what is an advantage of brachytherapy over external beam radiation?
Ans✓✓✓can use a higher dose of radiation
photodynamic therapy Ans✓✓✓uses a photosensitizer to destroy cancer
cells
photosensitizer is absorbed, stays in cancer cells longer than normal cells
cells exposed to low intensity laser light, photosensitizer absorbs light
and resulting chemical reaction kills cancer cells sparing most normal
ones
for what tumours is photodynamic therapy used? Ans✓✓✓tumours in
some organ linings
remove blockages from esophageal/lung tumours
what are the 3 goals of systemic therapy? Ans✓✓✓minimize side effects
(control cancer with minimal adverse effects)
, slow growth (kill metastasized cells and stop spread)
relieve symptoms
what is the most common form of systemic therapy?
Ans✓✓✓chemotherapy
4 types of systemic therapies Ans✓✓✓conventional chemo
hormone therapy
biological therapy/immunotherapy
systemic radiation
conventional chemo Ans✓✓✓cytotoxic drugs non-selectively kill all
actively dividing cells
e.g. doxorubicin
hormone therapy Ans✓✓✓inhibits hormone-induced tumour growth by
manipulating homeostatic control pathways
tamoxifen Ans✓✓✓blocks estrogen receptor in breast cancer cells,
preventing estrogen from acting on the cells
cells must express ER (ER+) to be effective
finasteride Ans✓✓✓blocks testosterone in prostate cancer