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Oxygenation and Perfusion NUR 111 2026 – 120+ NCLEX Questions & Answers – DVT, COPD, Pulmonary Embolism & Heart Failure

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This document contains 120+ structured NCLEX-style exam questions and detailed answers for Oxygenation and Perfusion (NUR 111) 2026. It provides comprehensive coverage of cardiovascular and respiratory pathophysiology, nursing assessment findings, priority interventions, laboratory interpretation, oxygen therapy management, and evidence-based care planning. The content is organized in a clear question-and-answer format aligned with the nursing process (assessment, diagnosis, planning, implementation, evaluation) and NCLEX cognitive levels. The material thoroughly reviews perfusion-related concepts including pulse deficits (apical–radial discrepancy), hematocrit interpretation in hypoxia, early signs of myocardial infarction in elderly women, prevention of cardiovascular disease (smoking cessation), excess fluid volume interventions, deep vein thrombosis (DVT) assessment findings, postoperative thrombus risk factors (orthopedic surgery, obesity), anticoagulation priorities (heparin and bleeding risk), and prevention of pulmonary embolism. It also addresses congestive heart failure manifestations such as paroxysmal nocturnal dyspnea and priority nursing diagnoses including impaired gas exchange. Respiratory topics include oxygen delivery systems (nasal cannula for 24% at 2 L/min), laboratory interpretation (low hemoglobin 8.3 as a critical oxygenation concern), COPD pathophysiology, hypoxic drive considerations, bronchodilator therapy, antibiotic indications, dietary management for COPD (high protein, high fat, low carbohydrate), pursed-lip and abdominal breathing techniques, pulmonary embolism assessment priorities, and postoperative DVT prevention strategies using pneumatic compression devices and leg exercises. The document emphasizes clinical reasoning, prioritization, and safety-based decision-making consistent with NCLEX testing standards and foundational nursing coursework. It integrates pathophysiology with bedside nursing interventions to reinforce exam readiness and patient-centered care planning. This resource is particularly suitable for: Practical Nursing (PN/LPN) students Associate Degree in Nursing (ADN) students Bachelor of Science in Nursing (BSN) students NUR 111 students NCLEX-PN candidates NCLEX-RN candidates Foundations and Adult Health nursing students It is relevant for courses such as: NUR 111 Oxygenation and Perfusion Fundamentals of Nursing Adult Health I Medical-Surgical Nursing Pathophysiology for Nurses NCLEX Preparation Keywords: NUR 111 Oxygenation and Perfusion 2026, NCLEX Cardiovascular Questions, Deep Vein Thrombosis DVT Nursing, Pulmonary Embolism Priority Diagnosis, COPD Nursing Interventions, Hypoxic Drive COPD, Pulse Deficit Assessment, Paroxysmal Nocturnal Dyspnea, Heparin Bleeding Risk, Oxygen Delivery Nasal Cannula 24 Percent, Hemoglobin 8.3 Interpretation, Excess Fluid Volume Nursing Care, Pursed Lip Breathing COPD, Orthopedic Surgery DVT Risk, Impaired Gas Exchange Nursing Diagnosis

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OXYGENATION AND PERFUSION
NUR 111 (NCLEX QUESTIONS)
2026 EXAM QUESTIONS AND
ANSWERS | 100% PASS



Which of the following assessment findings would suggest to the nurse that

a Patient is at risk for alterations in perfusion?

1. Blood pressure 110/68 mmHg

2. Apical heart rate 80; radial beats per minute 68

,3. Respiratory rate 20 per minute


4. Temperature 98.8°F - 🧠 ANSWER ✔✔Answer


2. Apical heart rate 80; radial beats per minute 68.

• Rationale:

• The number of radial beats per minute is 12 beats slower than the apical

rate of 80 per minute. This indicates weak contractions of the left ventricle

and could lead to alterations in perfusion. The other assessment findings

are within normal limits.

• Nursing Process: Assessment

• Cognitive Level: Analyzing

• Client Need: Physiological Integrity

A Patient is admitted with complaints of shortness of breath of 2 weeks

duration. Which of the following laboratory findings would support the

finding that the Patient is at risk for an alteration in perfusion?




1. Increased hematocrit

2. Decreased BUN

, 3. Increased blood sugar


4. Increased sedimentation rate - 🧠 ANSWER ✔✔1. Increased hematocrit.


• Rationale:

• Hematocrit is the percentage of the blood that is erythrocytes, which

contain the hemoglobin that carries oxygen. Long-term hypoxia may result

in the body's attempt to increase oxygen-carrying capacity by increasing

erythrocyte production. This can lead to an alteration in the client's

perfusion. BUN is a measure of blood urea nitrogen, not oxygen-carrying

capacity. Increases in blood sugar and sedimentation rate are not directly a

measure of oxygenation.

• Nursing Process: Assessment

• Cognitive Level: Analyzing

• Client Need: Physiological Integrity

• Learning Outcome: 5. Outline diagnostic and laboratory tests to determine

the individual's perfusion status.

A Patient tells the nurse that he does not want to develop the same heart

problems that his parents experienced. Which of the following should the

nurse instruct this client?


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