What organ produces the main digestive enzyme for starch breakdown? What is this enzyme
named? correct answers Exocrine Pancreas
Amylase
Explain the passive transport of glucose into and out of the intestinal epithelial cell (transporters
in each end of the cell).
Of these passive transporters which has a higher Km for glucose, the transporter on the lumen
surface or on the basolateral membrane (membrane near blood vessel; logic this out)? correct
answers Pancreases creates a-amylase
this cleaves glucose at its a1-4 linkages
individual glucoses then travel through the SGLUT1 transporter from the intestine to the
intestinal epithelial cell with Na+
(Na+ is kept at a gradient through the 3Na+/2K+ pump)
glucose is then further transported to the hepatoportal vasculature.
The transporter on the basolateral membrane due to the Glut 4 Translocation
What is the blood vessel that carries glucose from the digestive tract called? correct answers
Hepatic Portal Vein
Describe the cori cycle? (what 2 organs are involved, what 2 main metabolites are
involved)Explain why this must occur, including why the metabolites involved have to be
involved correct answers Skeletal Muscle Red Blood Cells and Liver
Glucose is metabolized to pyruvate and then to lactate in muscle, the lactate is released into the
blood and carried to the liver, where it is reconverted to pyruvate and used for gluconeogenesis,
and the resulting glucose is released and travels back to muscle.
When does a monogastric herbivore make glycogen, why correct answers (think rabbits)
In the fed state,
Glycogenesis; glucose enters hepatocytes via GLUT2 and is phosphorylated by glucokinase and
used to synthesize glycogen by glycogen synthase
When would a carnivore make glycogen, why correct answers (think cats)
never have huge insulin amount, never eats glucose, never stores glycogen
What 2 tissues store glycogen correct answers Liver and Skeletal Muscles
Based on your understanding of glycogen synthesis and regulation would a pig or cow store
more glycogen correct answers pig, cows do not make glycogen
Through glycogenolysis, glycogen is broken down to (2 things) correct answers glucose-1-
phosphate and glucose