NGR 6172 Quiz 3 (Chapters 70 - 76 and Chapters 78 - 82)
Questions With Complete Solutions
What bacteria does Vancomycin cover?
(Non-beta-lactam ABX)
MRSA
C. diff (oral only)
Serious G (+) infections in beta-lactam allergic pts
What bacteria does Telavancin cover?
(Synthetic Vancomycin Derivative)
G+ bacteria, including MRSA
Complicated skin infections
Adverse Fx of Telavancin
(Synthetic Vancomycin Derivative)
Taste changes
Foamy urine
QT prolongation
Nephrotoxicity
Teratogenic - avoid in pregnancy
Aztreonam bacterial coverage
(monobactam)
,Serious G (−) infections
Alt for pts w/ PCN/cephalosporin allergy
Aztreonam Adverse Fx
(monobactam)
Generally well tolerated
Occasional GI upset
Rash
Uses for Fosfomycin
Lower uncomplicated UTI in women + 1st Line for Acute
Cystitis in Non-Pregnant Women
Adverse Fx of Fosfomycin
Diarrhea + Nausea
HA + Vaginitis
Tetracycline Coverage
Most Gram (+) & Gram (-) bacteria
Mycoplasma pneumoniae
Lyme disease
Anthrax
H. pylori
Adverse Fx of Tetracycline
Children: Bone growth suppression + teeth discoloration
GI irritation
Superinfection
, Hepatotoxic + Nephrotoxic + Vestibulotoxic
Photosensitivity
Drug + Food Interactions for Tetracyclines
↓ Absorption with:
- Calcium + Iron + Mg
- Milk products
- Laxatives + Antacids
They form nonabsorbable chelates
Tetracycline contraindications
Pregnant women
Breastfeeding women
Children under 8 YO
Uses for Macrolides
(Erythromycin, Clarithromycin, Azithromycin)
Broad-spectrum ABX
Used if pt allergic to PCN
Active against most gram (+) & some gram (-) bacteria
Uses for Erythromycin
(Type of Macrolide)
Acute diphtheria
Chlamydia
Questions With Complete Solutions
What bacteria does Vancomycin cover?
(Non-beta-lactam ABX)
MRSA
C. diff (oral only)
Serious G (+) infections in beta-lactam allergic pts
What bacteria does Telavancin cover?
(Synthetic Vancomycin Derivative)
G+ bacteria, including MRSA
Complicated skin infections
Adverse Fx of Telavancin
(Synthetic Vancomycin Derivative)
Taste changes
Foamy urine
QT prolongation
Nephrotoxicity
Teratogenic - avoid in pregnancy
Aztreonam bacterial coverage
(monobactam)
,Serious G (−) infections
Alt for pts w/ PCN/cephalosporin allergy
Aztreonam Adverse Fx
(monobactam)
Generally well tolerated
Occasional GI upset
Rash
Uses for Fosfomycin
Lower uncomplicated UTI in women + 1st Line for Acute
Cystitis in Non-Pregnant Women
Adverse Fx of Fosfomycin
Diarrhea + Nausea
HA + Vaginitis
Tetracycline Coverage
Most Gram (+) & Gram (-) bacteria
Mycoplasma pneumoniae
Lyme disease
Anthrax
H. pylori
Adverse Fx of Tetracycline
Children: Bone growth suppression + teeth discoloration
GI irritation
Superinfection
, Hepatotoxic + Nephrotoxic + Vestibulotoxic
Photosensitivity
Drug + Food Interactions for Tetracyclines
↓ Absorption with:
- Calcium + Iron + Mg
- Milk products
- Laxatives + Antacids
They form nonabsorbable chelates
Tetracycline contraindications
Pregnant women
Breastfeeding women
Children under 8 YO
Uses for Macrolides
(Erythromycin, Clarithromycin, Azithromycin)
Broad-spectrum ABX
Used if pt allergic to PCN
Active against most gram (+) & some gram (-) bacteria
Uses for Erythromycin
(Type of Macrolide)
Acute diphtheria
Chlamydia
