WGU D236 Patho - Megan/Shay’s Study Guides
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What are common causes of cirrhosis? - Answer--ETOH
-Viral hepatitis (HEP C)
- Autoimmune hepatitis
-Drugs and chemicals (aetaminophen or anything else
hepatotoxic)
Complications of cirrhosis? - Answer-#Ascites
#Edema
#Portal hypertension (elevated BP throghout entire portal
venous system)
#Esophageal varices (engorged varicose veins on the low
esophagus weaken/rupture).
#Encephalopathy
#Respiratory distress
#Coagulation defects
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Hepatocytes do not function properly in cirrhosis, leading
to the following: _____________, _________________,
___________________, _______________,
_____________, __________________. - Answer-
#Inability to detoxify compound in the blood
#Increased toxin exposure
#Decreased bile - decreased lipid digestion/absorption
#Hyperbilirubinemia - jaundice
#Bleeding resulting from portal HTN
#Decreased synthesis of clotting factors - excessive
bleeding
#Hepatic encephalopathy - confusion, impaired cognition
What is pancreatitis? - Answer-Inflammation of the
pancreas that causes pancreatic insufficiency,
malabsorption, and diabetes. Pancreatitis can be an acute
or chronic disorder.
What is acute pancreatitis and what are its causes and
manifestations? - Answer-Acute pancreatitis is a sudden,
short-term episode of inflammation.
Causes:
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#Gallstones
#Excessive alcohol use
#High blood triglycerides
#Abdominal injury
#Certain medications and toxins
Manifestations:
#Abdominal pain
#N/V (following significant alcohol intake)
#Cullen sign (blue discoloration around the umbilicus is a
hallmark)
What is chronic pancreatitis and what are its causes,
manifestations, and complications? - Answer-Chronic
pancreatitis is the recurring destruction of the pancreatic
tissue that results in atrophy, fibrosis, scarring and the
development of calcification within the gland.
Causes:
#Gallstones (obstruct the flow of bile and pancreatic
secretions into the duodenum; backs up into the pancreas
and it starts autodigesting itself).
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#Alcohol (increased secretion of pancreatic enzymes and
sphincter of oddi contracts; enzymes pack up into
pancreas).
Manifestations:
#Severe epigastric pain
#Vomiting
Complications:
#Hemorrhage
#Hypovolemic shock (massive inflammatory response that
causes capillary leak)
#Circulatory collapse
#Peritonitis (enzymes escape into peritoneal cavity,
causing inflammation)
What occurs during gas exchange?
Erythropoietin is secreted into the bloodstream.
Oxygen moves across the alveolar membrane into the
bloodstream.