NR 507 EDAPT WEEK 7- CNS SENSORY AND MOTOR
DISORDERS ADVANCED PATHOPHYSIOLOGY
(CHAMBERLAIN UNIVERSITY)
NR 507 EDAPT WEEK 7- CNS SENSORY
AND MOTOR DISORDERS ADVANCED
PATHOPHYSIOLOGY
,Neurodegenerative disorders progressively damage brain regions, causing tremors, paralysis, cognitive decline,
memory loss, and speech or language difficulties. These conditions, such as dementia and Parkinson’s disease, can
significantly affect families even before full care is needed.
Learning Module Focus & Outcomes:
CO 1: Analyze pathophysiology of selected diseases across the lifespan.
CO 2: Examine how physiological mechanisms can be supported or altered via therapies.
CO 3: Identify risk factors for selected diseases across the lifespan.
CO 4: Apply advanced pathophysiology in diagnosing and treating health problems in specific populations.
Introduction to
Neurodegenerative Disorders
Neurodegenerative disorders progressively target and
destroy certain areas of brain function. This leads to tremors,
paralysis, reduced cognitive function, poor memory recall,
and speech and/or language problems. These debilitating
conditions may have a significant impact on friends and
family even before a client requires total care. Dementia and
Parkinson’s disease are two examples of common
neurodegenerative conditions.
This learning module focuses on the disease process of
neurodegenerative disorders and enables you to meet the
following course outcomes:
• CO 1: Analyze pathophysiologic mechanisms
associated with selected disease states across the
lifespan.
• CO 2: Examine the way in which homeostatic,
adaptive, and compensatory physiological
mechanisms can be supported and/or altered through
specific therapeutic interventions across the lifespan.
• CO 3: Distinguish risk factors associated with selected
disease states across the lifespan.
• CO 4: Integrate advanced pathophysiological concepts
in the diagnosis and treatment of health problems in
selected populations.
, Characteristics of
Neurodegenerative Disorders
Which of the following is a common characteristic of
neurodegenerative disorders?
Reversible neurological deficits
Rapid progression and immediate onset of symptoms
Progressive loss of structure or function of neurons
Primarily affecting the peripheral nervous system
Neurodegenerative disorders are primarily characterized by
the progressive degeneration of the structures and functions
of the brain (not the peripheral nervous system), especially
neurons. This process is usually gradual and worsens over
time (not rapidly), leading to irreversible (not reversible)
symptoms, including memory loss, impaired judgment, and
Risk Factors for
Neurodegenerative Disorders
motor dysfunction.
, Which of the following are risk factors for developing
neurodegenerative disorders? Select all that apply.
Genetic predisposition
History of traumatic brain injuries
Aging
High levels of physical activity in early adulthood
Exposure to certain environmental toxins
Genetic predisposition and aging are well-known risk factors
for neurodegenerative disorders. As individuals age, the risk
of diseases like Alzheimer's and Parkinson's increases.
Exposure to environmental toxins has been linked to an
increased risk of neurodegenerative diseases. History of
traumatic brain injuries is also considered a risk factor,
particularly for conditions such as Alzheimer's disease.
High levels of physical activity in early adulthood can reduce
the risk of neurodegenerative diseases.
Differentiating Neurodegenerative Disorders
Which neurodegenerative disorder is primarily caused by the
destruction of dopaminergic neurons in the substantia nigra of
the brain?
Huntington's disease
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Parkinson's disease
Parkinson's disease is caused by the progressive loss of
dopamine- producing neurons in the substantia nigra. This
loss leads to the primary symptoms of Parkinson's, such as
tremors, rigidity, bradykinesia (slowness of movement), and
postural instability.
Although the other options are neurodegenerative diseases,
they exhibit different pathophysiological characteristics.
Neurodegenerative
Disorders Affecting Motor
Function
Neurodegenerative disorders as a group cause progressive
degeneration of the structure and function of the nervous
system.
DISORDERS ADVANCED PATHOPHYSIOLOGY
(CHAMBERLAIN UNIVERSITY)
NR 507 EDAPT WEEK 7- CNS SENSORY
AND MOTOR DISORDERS ADVANCED
PATHOPHYSIOLOGY
,Neurodegenerative disorders progressively damage brain regions, causing tremors, paralysis, cognitive decline,
memory loss, and speech or language difficulties. These conditions, such as dementia and Parkinson’s disease, can
significantly affect families even before full care is needed.
Learning Module Focus & Outcomes:
CO 1: Analyze pathophysiology of selected diseases across the lifespan.
CO 2: Examine how physiological mechanisms can be supported or altered via therapies.
CO 3: Identify risk factors for selected diseases across the lifespan.
CO 4: Apply advanced pathophysiology in diagnosing and treating health problems in specific populations.
Introduction to
Neurodegenerative Disorders
Neurodegenerative disorders progressively target and
destroy certain areas of brain function. This leads to tremors,
paralysis, reduced cognitive function, poor memory recall,
and speech and/or language problems. These debilitating
conditions may have a significant impact on friends and
family even before a client requires total care. Dementia and
Parkinson’s disease are two examples of common
neurodegenerative conditions.
This learning module focuses on the disease process of
neurodegenerative disorders and enables you to meet the
following course outcomes:
• CO 1: Analyze pathophysiologic mechanisms
associated with selected disease states across the
lifespan.
• CO 2: Examine the way in which homeostatic,
adaptive, and compensatory physiological
mechanisms can be supported and/or altered through
specific therapeutic interventions across the lifespan.
• CO 3: Distinguish risk factors associated with selected
disease states across the lifespan.
• CO 4: Integrate advanced pathophysiological concepts
in the diagnosis and treatment of health problems in
selected populations.
, Characteristics of
Neurodegenerative Disorders
Which of the following is a common characteristic of
neurodegenerative disorders?
Reversible neurological deficits
Rapid progression and immediate onset of symptoms
Progressive loss of structure or function of neurons
Primarily affecting the peripheral nervous system
Neurodegenerative disorders are primarily characterized by
the progressive degeneration of the structures and functions
of the brain (not the peripheral nervous system), especially
neurons. This process is usually gradual and worsens over
time (not rapidly), leading to irreversible (not reversible)
symptoms, including memory loss, impaired judgment, and
Risk Factors for
Neurodegenerative Disorders
motor dysfunction.
, Which of the following are risk factors for developing
neurodegenerative disorders? Select all that apply.
Genetic predisposition
History of traumatic brain injuries
Aging
High levels of physical activity in early adulthood
Exposure to certain environmental toxins
Genetic predisposition and aging are well-known risk factors
for neurodegenerative disorders. As individuals age, the risk
of diseases like Alzheimer's and Parkinson's increases.
Exposure to environmental toxins has been linked to an
increased risk of neurodegenerative diseases. History of
traumatic brain injuries is also considered a risk factor,
particularly for conditions such as Alzheimer's disease.
High levels of physical activity in early adulthood can reduce
the risk of neurodegenerative diseases.
Differentiating Neurodegenerative Disorders
Which neurodegenerative disorder is primarily caused by the
destruction of dopaminergic neurons in the substantia nigra of
the brain?
Huntington's disease
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Parkinson's disease
Parkinson's disease is caused by the progressive loss of
dopamine- producing neurons in the substantia nigra. This
loss leads to the primary symptoms of Parkinson's, such as
tremors, rigidity, bradykinesia (slowness of movement), and
postural instability.
Although the other options are neurodegenerative diseases,
they exhibit different pathophysiological characteristics.
Neurodegenerative
Disorders Affecting Motor
Function
Neurodegenerative disorders as a group cause progressive
degeneration of the structure and function of the nervous
system.
