NR 293 - EXAM 1 Questions and
Answers
1. Drug correct answer: Any chemical that attects the physiologic processes of a living organism
2. Pharmacology correct answer: The study or science of drugs
3. Chemical Name correct answer: Describes the drug's chemical composition and molecular
structure (not usually used in nursing)
4. Generic Name correct answer: Name given by the United States Adopted Names council. The
universal name, like ibuprofen or acetaminophen
5. Trade Name correct answer: AKA proprietary name. The drug has a registered trademark, use of
the name is restricted by the drug's patent owner. Ex is Motrin and Advil, they are both ibuprofen
6. Pharmaceutics correct answer: The study of how various drug forms influence the way in
which the drug attects the body. Oral, rectal, transdermal, etc.
7. Pharmacodynamics correct answer: The study of what the drug does to the body. The
mechanism of drug actions in living tissues and drug-receptor relationships
8. Pharmacotherapeutics correct answer: The clinical use of drugs to prevent and treat
disease. Defines principles of drug actions- the cellular processes that change in response to the
presence of drug molecules. Drugs are organized into pharmacologic classes, like antihypertensives.
Ex correct answer: elderly taking baby aspirin to prevent strokes
9. Pharmacognosy correct answer: The study of natural drug sources, like plants, animals and
minerals.
10. Pharmaceutic Properties correct answer: Ditterent drug dosage forms have
ditterent properties. Dosage form deter- mines the rate of drug dissolution. Enteric-coated tablets
protect patients from stomach irritation.
11. Fastest Route of Oral Drug Absorption correct answer: 1. Oral
disintegration, buccal tabs, and oral soluble wafers
2. Liquids, elixirs, and syrups
3. Suspension solutions
4. Powders
,5. Capsules
6. Tablets
7. Coated tablets
8. Enteric-coated tabletes
12. Pharmacokinetics correct answer: The study of what the body does to the drug. A
drug's time to onset of action, time to peak ettect, and duration of action.
-Absorption, Distribution, Metabolism, Excretion
, 13. Pharmacokinetics correct answer: Absorption correct answer: Movement of a
drug from its site of administration into the blood- stream for distribution to the tissues.
14. Bioavailability correct answer: A measure of the extent of drug absorption for a given
drug and route. Giving a med through the IV, you will have 100% of the med in the bloodstream,
none is lost.
15. First-Pass Effect correct answer: The initial metabolism in the liver of a drug
absorbed from the GI tract before the drug reaches systemic circulation. If you give a PO med, the
GI system digests, liver transforms, and then it reaches the bloodstream. Not 100% of the med
reaches the bloodstream, you lose some as it travels.
16. Enteral Route of Drug Administration correct answer: The drug is absorbed
into the systemic circulation through
the oral or gastric mucosa or the small intestine. Types of enteral are oral, sublingual, buccal, and rectal.
17. Parenteral Route of Drug Administration correct answer: Though an IV,
IM, subcutaneous, intradermal, intraarterial, intrathecal, and intraarticular
18. Topical Route of Drug Administration correct answer: Skin, eyes, ears, nose,
lungs, rectum, vagina
19. Pharmacokinetics correct answer: Distribution correct answer: The transport of
a drug by the bloodstream to its site of action. Protein-binding, water-soluble vs fat-soluble,
blood-brain barrier.
20. Protein-Binding Drugs correct answer: After you take the medication, it is in the blood
attached to protein, mainly albumin. When the drug binds to albumin, it works as a slow release, only
the free unbound drug is therapeutic. The bound drug is essentially inactive. Type of drugs that are
protein-binding are blood thinners. If a patient is deficient in albumin, there is a problem of too much
free-drug.
21. Pharmacokinetics correct answer: Metabolism/Biotransformation correct
answer: The biochemical alteration of a drug
into an inactive metabolite, a more soluble compound, a more potent active metabolite, or a less active
metabolite. Transformed mainly in the liver, but also skeletal muscle, kidneys, lungs, plasma, intestinal
mucosa.
22. Factors the Decrease Metabolism correct answer: Cardiovascular dysfunction,
renal insuflciency, starvation, ob-
structive jaundice, slow acetylator, and ketoconazole therapy
23. Factors the Increase Metabolism correct answer: Fast acetylator, barbiturate
Answers
1. Drug correct answer: Any chemical that attects the physiologic processes of a living organism
2. Pharmacology correct answer: The study or science of drugs
3. Chemical Name correct answer: Describes the drug's chemical composition and molecular
structure (not usually used in nursing)
4. Generic Name correct answer: Name given by the United States Adopted Names council. The
universal name, like ibuprofen or acetaminophen
5. Trade Name correct answer: AKA proprietary name. The drug has a registered trademark, use of
the name is restricted by the drug's patent owner. Ex is Motrin and Advil, they are both ibuprofen
6. Pharmaceutics correct answer: The study of how various drug forms influence the way in
which the drug attects the body. Oral, rectal, transdermal, etc.
7. Pharmacodynamics correct answer: The study of what the drug does to the body. The
mechanism of drug actions in living tissues and drug-receptor relationships
8. Pharmacotherapeutics correct answer: The clinical use of drugs to prevent and treat
disease. Defines principles of drug actions- the cellular processes that change in response to the
presence of drug molecules. Drugs are organized into pharmacologic classes, like antihypertensives.
Ex correct answer: elderly taking baby aspirin to prevent strokes
9. Pharmacognosy correct answer: The study of natural drug sources, like plants, animals and
minerals.
10. Pharmaceutic Properties correct answer: Ditterent drug dosage forms have
ditterent properties. Dosage form deter- mines the rate of drug dissolution. Enteric-coated tablets
protect patients from stomach irritation.
11. Fastest Route of Oral Drug Absorption correct answer: 1. Oral
disintegration, buccal tabs, and oral soluble wafers
2. Liquids, elixirs, and syrups
3. Suspension solutions
4. Powders
,5. Capsules
6. Tablets
7. Coated tablets
8. Enteric-coated tabletes
12. Pharmacokinetics correct answer: The study of what the body does to the drug. A
drug's time to onset of action, time to peak ettect, and duration of action.
-Absorption, Distribution, Metabolism, Excretion
, 13. Pharmacokinetics correct answer: Absorption correct answer: Movement of a
drug from its site of administration into the blood- stream for distribution to the tissues.
14. Bioavailability correct answer: A measure of the extent of drug absorption for a given
drug and route. Giving a med through the IV, you will have 100% of the med in the bloodstream,
none is lost.
15. First-Pass Effect correct answer: The initial metabolism in the liver of a drug
absorbed from the GI tract before the drug reaches systemic circulation. If you give a PO med, the
GI system digests, liver transforms, and then it reaches the bloodstream. Not 100% of the med
reaches the bloodstream, you lose some as it travels.
16. Enteral Route of Drug Administration correct answer: The drug is absorbed
into the systemic circulation through
the oral or gastric mucosa or the small intestine. Types of enteral are oral, sublingual, buccal, and rectal.
17. Parenteral Route of Drug Administration correct answer: Though an IV,
IM, subcutaneous, intradermal, intraarterial, intrathecal, and intraarticular
18. Topical Route of Drug Administration correct answer: Skin, eyes, ears, nose,
lungs, rectum, vagina
19. Pharmacokinetics correct answer: Distribution correct answer: The transport of
a drug by the bloodstream to its site of action. Protein-binding, water-soluble vs fat-soluble,
blood-brain barrier.
20. Protein-Binding Drugs correct answer: After you take the medication, it is in the blood
attached to protein, mainly albumin. When the drug binds to albumin, it works as a slow release, only
the free unbound drug is therapeutic. The bound drug is essentially inactive. Type of drugs that are
protein-binding are blood thinners. If a patient is deficient in albumin, there is a problem of too much
free-drug.
21. Pharmacokinetics correct answer: Metabolism/Biotransformation correct
answer: The biochemical alteration of a drug
into an inactive metabolite, a more soluble compound, a more potent active metabolite, or a less active
metabolite. Transformed mainly in the liver, but also skeletal muscle, kidneys, lungs, plasma, intestinal
mucosa.
22. Factors the Decrease Metabolism correct answer: Cardiovascular dysfunction,
renal insuflciency, starvation, ob-
structive jaundice, slow acetylator, and ketoconazole therapy
23. Factors the Increase Metabolism correct answer: Fast acetylator, barbiturate
