Pharmacology Principles Elsevier Exam
UPDATED QUESTIONS AND CORRECT
ANSWERS
A patient with end-stage renal disease is admitted to the hospital with a complication and is in
need of drug therapy. Which pharmacokinetic phase is affected by a compromised renal
system?
Excretion
Absorption
Distribution
Metabolism - CORRECT ANSWER Excretion
A nurse is educating a patient who is prescribed warfarin. The nurse advises the patient to
avoid taking aspirin and explains that taking both drugs together may cause excessive
bleeding. What is this phenomenon called?
Additive effect
Incompatibility
Synergistic effect
Antagonistic effect - CORRECT ANSWER Additive effect
Pharmacokinetics involves the study of which factor?
, Physiologic interactions of drugs
Interactions among various drugs
Adverse reactions to medications
Distribution rates among various body compartments - CORRECT
ANSWER Distribution rates among various body compartments
The nurse will administer a drug to a patient via the oral route. What condition interferes with
the optimum therapeutic effect of a drug given by this route?
Seizure disorder
Left lower leg amputation
Coronary artery bypass graft
Resection of the small intestine - CORRECT ANSWER Resection of the small
intestine
Which enzyme is responsible for the metabolism of drugs in the liver during first-pass
metabolism?
Ptyalin
Gastric lipase
P450 enzymes
UPDATED QUESTIONS AND CORRECT
ANSWERS
A patient with end-stage renal disease is admitted to the hospital with a complication and is in
need of drug therapy. Which pharmacokinetic phase is affected by a compromised renal
system?
Excretion
Absorption
Distribution
Metabolism - CORRECT ANSWER Excretion
A nurse is educating a patient who is prescribed warfarin. The nurse advises the patient to
avoid taking aspirin and explains that taking both drugs together may cause excessive
bleeding. What is this phenomenon called?
Additive effect
Incompatibility
Synergistic effect
Antagonistic effect - CORRECT ANSWER Additive effect
Pharmacokinetics involves the study of which factor?
, Physiologic interactions of drugs
Interactions among various drugs
Adverse reactions to medications
Distribution rates among various body compartments - CORRECT
ANSWER Distribution rates among various body compartments
The nurse will administer a drug to a patient via the oral route. What condition interferes with
the optimum therapeutic effect of a drug given by this route?
Seizure disorder
Left lower leg amputation
Coronary artery bypass graft
Resection of the small intestine - CORRECT ANSWER Resection of the small
intestine
Which enzyme is responsible for the metabolism of drugs in the liver during first-pass
metabolism?
Ptyalin
Gastric lipase
P450 enzymes
