(VERSION A, TEST SCORE 94%) RESP 2250
What is a drug? any chemical that alters the organisms functions or processes
What is an orphan drug? A drug for the diagnosis or treatment of a rare disease
study of drugs, including their origins, properties and interactions with living
What is pharmacology?
organisms
Name assigned to a chemical by the United States adopted name (USAN) council
What is the generic name of a drug? when the chemical appears to have therapeutic use and manufacturers wish to
market drug.
What is the trade name of a drug? Brand-name or trademarked name by a particular manufacturer.
- Patient's name
- Drug name (should be generic)
What is required on a drug prescription? - Drug dose
- Frequency of administration
- Duration of treatment (optional)
- Doses are smaller than doses given systemically (oral or injection)
- Fewer and less severe side effects
What are the advantages of inhaled
- Onset of drug action is rapid
aerosols?
- Delivery targeted to intended organ
- Painless, safe, convenient
"Every"
What does "q" mean in pharmacology?
(q4 = every 4 hrs)
What does "BID" mean in pharmacology? Twice a day
What does "TID" mean in pharmacology? Three times a day
What does "QID" mean in pharmacology? Four times a day
What does "HS" mean in pharmacology? Hours of sleep meaning at bed time
What does "PRN" mean in pharmacology? As needed
, What does "CUM" mean in pharmacology? With
What does "S" mean in pharmacology? Without
What does "A_" mean in pharmacology? Before
What does "P_" mean in pharmacology? Post or After
MDI = Metered Dose Inhalers
SVN = Small Volume
What are the common devices from drug
Nebulizers
delivery in RT?
HHN = Hand-Held Nebulizers (Same as SVN)
DPI = Dry powder inhaler
SMI = soft mist inhaler (new and limited)
- Absorption
What are the four factors that influence the - Distribution
course of a drug? - Metabolism
- Elimination
What is a receptor? Any cell components that combines with a drug to modify the function of that cell
What is an agonist? A drug that binds to a receptor and stimulates it (has an effect)
A drug that binds to a receptor, but causes no response. It also will not allow other
What is an antagonist?
chemicals to bind with it. (it blocks)
How are aerosolized meds better than Less side effects
systemic delivered drugs?
What is aerosol? A suspension of solid or liquid particles in gas
What is emitted dose? the mass of drug leaving the mouthpiece of the nebulizer as aerosol
Inertial impact = > 5um
Particle sizes by aerosol deposition Sedimentation = 1-5um
Brownian diffusion = < 3um
Upper airway (nose, larynx, trachea) = 5 to >50um
Lower aiways = 2-5um
Desired location of deposition by size..
Parenchyma (Alveolar region) = 1-3um
Parenchyma = <0.1um
Smallest particles (0.5 - 1um) are mostly During exhalation
cleared...
Difference between heterodispense and Hetero = many different particle sizes
monodispense? Mono = similar particle size
Particle size that reaches alveolar region? 1-3 um
What is the primary hazard of aerosol Adverse reaction
therapy?
Diff between holding chamber and space? Spacer has no valves
When sending a PT home W/ meds.. what For PTs to learn to effectively self-administer
is the goal?
If a small volume nebulizer is tilted... It doesnt work (PT needs to be upright)
What is the recommended dose for CBT? 15 mg/HR
What is the range of pulmonary deposition 1.5 to 3.0%
for SVN while on a MV?
Pentamidine and Ribavirin require... Private rooms, booths and special stations
NE or Norepinephrine is the Sympathetic nervous system
neurotransmitter for
ACH or acetylcholine is the Parasympathetic nervous system
neurotransmitter for
What is a drug? any chemical that alters the organisms functions or processes
What is an orphan drug? A drug for the diagnosis or treatment of a rare disease
study of drugs, including their origins, properties and interactions with living
What is pharmacology?
organisms
Name assigned to a chemical by the United States adopted name (USAN) council
What is the generic name of a drug? when the chemical appears to have therapeutic use and manufacturers wish to
market drug.
What is the trade name of a drug? Brand-name or trademarked name by a particular manufacturer.
- Patient's name
- Drug name (should be generic)
What is required on a drug prescription? - Drug dose
- Frequency of administration
- Duration of treatment (optional)
- Doses are smaller than doses given systemically (oral or injection)
- Fewer and less severe side effects
What are the advantages of inhaled
- Onset of drug action is rapid
aerosols?
- Delivery targeted to intended organ
- Painless, safe, convenient
"Every"
What does "q" mean in pharmacology?
(q4 = every 4 hrs)
What does "BID" mean in pharmacology? Twice a day
What does "TID" mean in pharmacology? Three times a day
What does "QID" mean in pharmacology? Four times a day
What does "HS" mean in pharmacology? Hours of sleep meaning at bed time
What does "PRN" mean in pharmacology? As needed
, What does "CUM" mean in pharmacology? With
What does "S" mean in pharmacology? Without
What does "A_" mean in pharmacology? Before
What does "P_" mean in pharmacology? Post or After
MDI = Metered Dose Inhalers
SVN = Small Volume
What are the common devices from drug
Nebulizers
delivery in RT?
HHN = Hand-Held Nebulizers (Same as SVN)
DPI = Dry powder inhaler
SMI = soft mist inhaler (new and limited)
- Absorption
What are the four factors that influence the - Distribution
course of a drug? - Metabolism
- Elimination
What is a receptor? Any cell components that combines with a drug to modify the function of that cell
What is an agonist? A drug that binds to a receptor and stimulates it (has an effect)
A drug that binds to a receptor, but causes no response. It also will not allow other
What is an antagonist?
chemicals to bind with it. (it blocks)
How are aerosolized meds better than Less side effects
systemic delivered drugs?
What is aerosol? A suspension of solid or liquid particles in gas
What is emitted dose? the mass of drug leaving the mouthpiece of the nebulizer as aerosol
Inertial impact = > 5um
Particle sizes by aerosol deposition Sedimentation = 1-5um
Brownian diffusion = < 3um
Upper airway (nose, larynx, trachea) = 5 to >50um
Lower aiways = 2-5um
Desired location of deposition by size..
Parenchyma (Alveolar region) = 1-3um
Parenchyma = <0.1um
Smallest particles (0.5 - 1um) are mostly During exhalation
cleared...
Difference between heterodispense and Hetero = many different particle sizes
monodispense? Mono = similar particle size
Particle size that reaches alveolar region? 1-3 um
What is the primary hazard of aerosol Adverse reaction
therapy?
Diff between holding chamber and space? Spacer has no valves
When sending a PT home W/ meds.. what For PTs to learn to effectively self-administer
is the goal?
If a small volume nebulizer is tilted... It doesnt work (PT needs to be upright)
What is the recommended dose for CBT? 15 mg/HR
What is the range of pulmonary deposition 1.5 to 3.0%
for SVN while on a MV?
Pentamidine and Ribavirin require... Private rooms, booths and special stations
NE or Norepinephrine is the Sympathetic nervous system
neurotransmitter for
ACH or acetylcholine is the Parasympathetic nervous system
neurotransmitter for
