PAT 202: Week 8- Liver Disorders Continued |
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Terms in this set (41)
- Is usually transmitted parenterally and sexually
transmitted
- Maternal-infant transmission occurs if the mother is
infected during the third trimester.
Risk factors:
- Immunosuppressed people or on
immunosuppressive drugs
What is hepatitis B? - Hemodialysis, multiple blood transfusions
- Multiple sex partners
- Share needles, syringes or other drug equipment
Prevention:
- Hepatitis B vaccine prevents the transmission and
development of hepatitis B
- Hepatitis B immunoglobulin provides post-exposure
prophylaxis against hepatitis B
, - Is usually transmitted parenterally
- Is responsible for most cases of posttransfusion
hepatitis
- Is also implicated in infections related to IV drug use
and human immunodeficiency viral (HIV) infection
- Coinfection with hepatitis B is common
What is hepatitis C? - Approximately 80% of those with hepatitis C
develop chronic liver disease
Risk factors:
- HBV infection
Prevention
- No vaccine is available
- Administer antiviral medications
- Hepatic cell necrosis, scarring, Kupffer cell
hyperplasia, and infiltration by mononuclear
phagocytes occur
- Inflammatory processes can damage and obstruct
What is the
bile canaliculi → cholestasis and obstructive jaundice
pathophysiology behind
- Cell-mediated immune mechanisms (e.g., cytotoxic T
hepatitis?
cells, T regulatory cells, and natural killer cells)
- Damage most severe in Hep B and Hep C
- Viruses cause liver cell apoptosis
- Hep associated with acute liver failure
- The clinical signs of viral hepatitis are similar,
including nausea, malaise, stomach pain, and jaundice
- The symptoms range from no symptoms to
fulminating hepatitis, with rapid onset of liver failure
What are the clinical and coma
manifestations of viral - Acute viral hepatitis causes abnormal liver function
hepatitis? test results
- ↑ serum aminotransferase values, ↑ aspartate
transaminase (AST) and ↑ alanine transaminase (ALT)
- Elevation may not be consistent with extent of
cellular damage
Questions and Answers
Save
Terms in this set (41)
- Is usually transmitted parenterally and sexually
transmitted
- Maternal-infant transmission occurs if the mother is
infected during the third trimester.
Risk factors:
- Immunosuppressed people or on
immunosuppressive drugs
What is hepatitis B? - Hemodialysis, multiple blood transfusions
- Multiple sex partners
- Share needles, syringes or other drug equipment
Prevention:
- Hepatitis B vaccine prevents the transmission and
development of hepatitis B
- Hepatitis B immunoglobulin provides post-exposure
prophylaxis against hepatitis B
, - Is usually transmitted parenterally
- Is responsible for most cases of posttransfusion
hepatitis
- Is also implicated in infections related to IV drug use
and human immunodeficiency viral (HIV) infection
- Coinfection with hepatitis B is common
What is hepatitis C? - Approximately 80% of those with hepatitis C
develop chronic liver disease
Risk factors:
- HBV infection
Prevention
- No vaccine is available
- Administer antiviral medications
- Hepatic cell necrosis, scarring, Kupffer cell
hyperplasia, and infiltration by mononuclear
phagocytes occur
- Inflammatory processes can damage and obstruct
What is the
bile canaliculi → cholestasis and obstructive jaundice
pathophysiology behind
- Cell-mediated immune mechanisms (e.g., cytotoxic T
hepatitis?
cells, T regulatory cells, and natural killer cells)
- Damage most severe in Hep B and Hep C
- Viruses cause liver cell apoptosis
- Hep associated with acute liver failure
- The clinical signs of viral hepatitis are similar,
including nausea, malaise, stomach pain, and jaundice
- The symptoms range from no symptoms to
fulminating hepatitis, with rapid onset of liver failure
What are the clinical and coma
manifestations of viral - Acute viral hepatitis causes abnormal liver function
hepatitis? test results
- ↑ serum aminotransferase values, ↑ aspartate
transaminase (AST) and ↑ alanine transaminase (ALT)
- Elevation may not be consistent with extent of
cellular damage
