USAHS PHARMACOLOGY FINAL EXAM WITH COMPREHENSIVE

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USAHS PHARMACOLOGY FINAL EXAM WITH
COMPREHENSIVE PRACTICE QUESTIONS AND
ANSWERS 2026-28 LATEST VERSION

What is the original NSAID? - CORRECT ANSWERS Asprin


What are the four properties of NSAIDs - CORRECT ANSWERS -
Decrease Inflammation
-Decrease elevated body temp assoc. w/ fever
-Decrease blood clotting by inhibiting platelet aggragation
(anticoagulation)
-Relieve mild-moderate pain (analgesia)


Antipyresis - CORRECT ANSWERS reducing an elevated body
temperature


What do NSAIDs interphere with? - CORRECT ANSWERS With
biosynthesis of prostaglandins


What are prostaglandins? - CORRECT ANSWERS Lipid like
compounds that are biologically active ecosanoids and include
thombroxanes and leukotrienes

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Ecosanoids - CORRECT ANSWERS are diverse lipids chiefly
derived from 20-carbon fatty acid (arachidonic acid) found on all
cell membranes.


How do Ecosanoids influence health? - CORRECT ANSWERS
Cardiovascular, respiratory, GI, Renal, nervous, and reproduction


Problems with excessive prostaglandin sythnesis (8): - CORRECT
ANSWERS Inflammation


Fever


Pain


Dysmenorrhea


Thrombus


Neoplasm


HTN


Colon Cancer

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dysmenorrhea - CORRECT ANSWERS painful menstruation


arachnodonic acid will make - CORRECT ANSWERS cyclo-
oxygenase


Cyclogenase will make - CORRECT ANSWERS prostalandins
unless NSAIDs block that


MOA of NSAID action (normal cell) - CORRECT ANSWERS
Normal cell ->


Physiologic stimulus (i.e excessive GI acid) -->


COX-1 "constitutive" -->


House keeping cells


Cox-1 - CORRECT ANSWERS "house keeping"


THE BENEFICIAL ONE


MOA of NSAID action (injured cell) - CORRECT ANSWERS
Injured Cell --->