PSIO 201--Exam 2-- University of Arizona EXAM,
MOST TESTED QUESTIONS AND VERIFIED
SOLUTIONS/GET IT 100% ACCURATE!! 2026!!
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Terms in this set (111)
Bone Types Long, Short, Flat, Irregular, Sesamoid, Sutural,
Pneumatized
Periosteum -Cover: Outer membrane of bone. (External)
-Connections: Continuous with tendons & joint
capsules.
-Anchored by: Perforating fibers.
Layers:
Fibrous (outer) → protection, attachment.
Osteogenic (inner) → bone growth & repair.
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Endosteum -Lines inner surface of bone, contains osteogenic
cells
-bone growth, repair, remodeling.
Why is bone considered an organ? It contains osseous (connective) tissue, blood
vessels, nerves, lymphatic vessels, cartilage, and
connective tissue coverings
Osteogenic Cells Stem cells formed from mesenchyme (embryonic
connective tissue)
(These differentiate into Osteoblasts)
Osteoblasts Build bone --> Bone Formation
-Immature bone cells
-Synthesize organic components of matrix
- Initiate Calcification: Take calcium from blood &
deposit it within the matrix by exocytosis.
Osteocytes -Maintenance of bone
-Mature bone cells
-Sense bone microdamage and mechanical forces
on bone, sending signals for repair
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Osteoclasts -Break down bone --> Bones resorption
-Release proteolytic enzymes & acids to degrade
collagen & release minerals to the blood.
These have the
1. Scaling zone (SZ)
2. Ruffled border (RB)
3. Functional Secretory Domain (FSD)
Bone Modeling Bone formed by osteoblasts without prior bone
resorption
Bone Remodeling Bone resorbed by osteoclasts and then formed by
osteoblasts
Cartilage Tissue Chondrocytes; gel-like substance containing
proteoglycan, elastic, collagen, or reticular fibers
Bone Tissue Osteocytes; solid ground substance containing
proteoglycans, collagen elastic fibers,
hydroxyapatite
Collagen -Provides flexibility & resistance to tension
Minerals -Provide firmness (resistance to compression)
Rickets Calcium deficiency due to lack of vitamin D leads
to flexible bones (bowed legs)
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