NR577/NR 577 Pharm only #2Advanced Psychopharmacology and Endocrine Therapeutics Review: Bipolar Disorder Management in Pregnancy and Valproic Acid Teratogenicity, Absence Seizures and Carbamazepine Contraindication, Migraine Treatment in Coronary Artery

NR577/NR 577 Pharm only #2Advanced Psychopharmacology and Endocrine Therapeutics Review: Bipolar Disorder Management in Pregnancy and Valproic Acid Teratogenicity, Absence Seizures and Carbamazepine Contraindication, Migraine Treatment in Coronary Artery Disease and Triptan Avoidance, Type 2 Diabetes Mellitus with Recurrent Hypoglycemia and Sulfonylurea Risk, GLP-1 Receptor Agonists for Cardiovascular Benefit and Weight Loss, SSRI First-Line Therapy for Generalized Anxiety Disorder, Bulimia Nervosa and Bupropion Contraindication, Antidepressant-Induced Mania in Bipolar Disorder, Lithium Narrow Therapeutic Index and Serum Monitoring, Levothyroxine Initiation and TSH Reassessment at 6–8 Week Exam Questions Verified and Provided with Complete A+ Graded Rationales Latest Updated 2026 1. A 28-year-old woman with bipolar disorder is newly pregnant (6 weeks). Which medication should be AVOIDED? A. Quetiapine B. Lamotrigine C. Valproic acid D. Lithium C. Valproic acid 2. A patient with absence seizures is mistakenly started on carbamazepine. What is the most likely outcome? A. Improved seizure control B. No clinical change C. Worsening seizure frequency D. Conversion to focal seizures C. Worsening seizure frequency 3. A patient with migraine headaches and coronary artery disease should avoid which medication? A. Propranolol B. Topiramate C. Sumatriptan D. Amitriptyline C. Sumatriptan 4. A patient with type 2 diabetes and recurrent hypoglycemia should avoid which medication class? A. GLP-1 receptor agonists B. SGLT2 inhibitors C. Metformin D. Sulfonylureas D. Sulfonylureas 5. Which diabetes medication provides cardiovascular benefit and weight loss? A. Sulfonylurea B. Insulin C. GLP-1 receptor agonist D. TZD C. GLP-1 receptor agonist 6. A patient asks for fast-acting medication for long-term anxiety control. Best response? A. Alprazolam B. Clonazepam C. Start an SSRI D. Propranolol daily C. Start an SSRI 7. Which antidepressant should be avoided in bulimia nervosa? A. Fluoxetine B. Sertraline C. Escitalopram D. Bupropion D. Bupropion 8. A bipolar patient on sertraline develops euphoria and decreased sleep. This represents: A. Intolerance B. Serotonin syndrome C. Antidepressant-induced mania D. Akathisia C. Antidepressant-induced mania 9. Which medication requires serum monitoring and has a narrow therapeutic index? A. Valproic acid B. Quetiapine C. Lithium D. Lamotrigine C. Lithium 10. When should TSH be rechecked after starting levothyroxine? A. 1 week B. 2 weeks C. 6-8 weeks D. 3 months C. 6-8 weeks 11. Which hyperthyroidism medication is preferred in first trimester pregnancy? A. Methimazole B. Propranolol C. Levothyroxine D. PTU D. PTU 12. A patient on methimazole develops fever and sore throat. This suggests: A. Thyroid storm B. Allergy C. Agranulocytosis D. Hypothyroidism C. Agranulocytosis 13. Which insulin provides basal coverage only? A. Lispro B. Regular C. NPH D. Glargine D. Glargine 14. Which insulin has the highest hypoglycemia risk? A. Glargine B. Lispro C. Detemir D. NPH D. NPH 15. ADHD patient with substance use disorder—best medication? A. Amphetamine salts B. Methylphenidate C. Atomoxetine D. Dexmethylphenidate C. Atomoxetine