,
, Clinical
Chemistry
TECHNIQUES, PRINCIPLES, CORRELATIONS
SIXTH EDITION
Michael L. Bishop, MS, CLS, MT(ASCP)
Director of Educational Services
Global Med Technologies
El Dorado Hills, California
Edward P. Fody, MD
Medical Director
Department of Pathology
Holland Hospital
Holland, Michigan
Larry E. Schoeff, MS, MT(ASCP)
Professor and Director, Medical Laboratory Science Program
University of Utah School of Medicine
Education Consultant, ARUP Laboratories
Salt Lake City, Utah
, Acquisitions Editor: John Goucher
Managing Editor: Meredith Brittain
Marketing Manager: Allison Noplock
Project Manager: Rosanne Hallowell
Designer: Stephen Druding
Compositor: ASI Maryland Composition
Sixth Edition
Copyright © 2010, 2005, 2000, 1996, 1992, 1985 by Lippincott Williams & Wilkins, a Wolters Kluwer
business.
351 West Camden Street 530 Walnut Street
Baltimore, MD 21201 Philadelphia, PA 19106
Printed in China
All rights reserved. This book is protected by copyright. No part of this book may be reproduced or
transmitted in any form or by any means, including as photocopies or scanned-in or other electronic
copies, or utilized by any information storage and retrieval system without written permission from
the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials ap-
pearing in this book prepared by individuals as part of their official duties as U.S. government em-
ployees are not covered by the above-mentioned copyright. To request permission, please contact
Lippincott Williams & Wilkins at 530 Walnut Street, Philadelphia, PA 19106, via email at permis-
, or via website at lww.com (products and services).
987654321
Library of Congress Cataloging-in-Publication Data
Clinical chemistry : techniques, principles, correlations / [edited by] Michael L. Bishop, Edward P.
Fody, Larry E. Schoeff. -- 6th ed.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-0-7817-9045-1 (alk. paper)
1. Clinical chemistry. I. Bishop, Michael L. II. Fody, Edward P. III. Schoeff, Larry E.
[DNLM: 1. Chemistry, Clinical--methods. 2. Clinical Chemistry Tests. QY 90 C6414 2010]
RB40.C576 2010
616.07'56--dc22
2008052929
DISCLAIMER
Care has been taken to confirm the accuracy of the information present and to describe generally
accepted practices. However, the authors, editors, and publisher are not responsible for errors or omis-
sions or for any consequences from application of the information in this book and make no warranty,
expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the
publication. Application of this information in a particular situation remains the professional respon-
sibility of the practitioner; the clinical treatments described and recommended may not be considered
absolute and universal recommendations.
The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage
set forth in this text are in accordance with the current recommendations and practice at the time of
publication. However, in view of ongoing research, changes in government regulations, and the con-
stant flow of information relating to drug therapy and drug reactions, the reader is urged to check the
package insert for each drug for any change in indications and dosage and for added warnings and pre-
cautions. This is particularly important when the recommended agent is a new or infrequently em-
ployed drug.
Some drugs and medical devices presented in this publication have Food and Drug Administration
(FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care
provider to ascertain the FDA status of each drug or device planned for use in their clinical practice.
To purchase additional copies of this book, call our customer service department at (800) 638-
3030 or fax orders to (301) 223-2320. International customers should call (301) 223-2300.
Visit Lippincott Williams & Wilkins on the Internet: http://www.lww.com. Lippincott Williams &
Wilkins customer service representatives are available from 8:30 am to 6:00 pm, EST.
, Clinical
Chemistry
TECHNIQUES, PRINCIPLES, CORRELATIONS
SIXTH EDITION
Michael L. Bishop, MS, CLS, MT(ASCP)
Director of Educational Services
Global Med Technologies
El Dorado Hills, California
Edward P. Fody, MD
Medical Director
Department of Pathology
Holland Hospital
Holland, Michigan
Larry E. Schoeff, MS, MT(ASCP)
Professor and Director, Medical Laboratory Science Program
University of Utah School of Medicine
Education Consultant, ARUP Laboratories
Salt Lake City, Utah
, Acquisitions Editor: John Goucher
Managing Editor: Meredith Brittain
Marketing Manager: Allison Noplock
Project Manager: Rosanne Hallowell
Designer: Stephen Druding
Compositor: ASI Maryland Composition
Sixth Edition
Copyright © 2010, 2005, 2000, 1996, 1992, 1985 by Lippincott Williams & Wilkins, a Wolters Kluwer
business.
351 West Camden Street 530 Walnut Street
Baltimore, MD 21201 Philadelphia, PA 19106
Printed in China
All rights reserved. This book is protected by copyright. No part of this book may be reproduced or
transmitted in any form or by any means, including as photocopies or scanned-in or other electronic
copies, or utilized by any information storage and retrieval system without written permission from
the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials ap-
pearing in this book prepared by individuals as part of their official duties as U.S. government em-
ployees are not covered by the above-mentioned copyright. To request permission, please contact
Lippincott Williams & Wilkins at 530 Walnut Street, Philadelphia, PA 19106, via email at permis-
, or via website at lww.com (products and services).
987654321
Library of Congress Cataloging-in-Publication Data
Clinical chemistry : techniques, principles, correlations / [edited by] Michael L. Bishop, Edward P.
Fody, Larry E. Schoeff. -- 6th ed.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-0-7817-9045-1 (alk. paper)
1. Clinical chemistry. I. Bishop, Michael L. II. Fody, Edward P. III. Schoeff, Larry E.
[DNLM: 1. Chemistry, Clinical--methods. 2. Clinical Chemistry Tests. QY 90 C6414 2010]
RB40.C576 2010
616.07'56--dc22
2008052929
DISCLAIMER
Care has been taken to confirm the accuracy of the information present and to describe generally
accepted practices. However, the authors, editors, and publisher are not responsible for errors or omis-
sions or for any consequences from application of the information in this book and make no warranty,
expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the
publication. Application of this information in a particular situation remains the professional respon-
sibility of the practitioner; the clinical treatments described and recommended may not be considered
absolute and universal recommendations.
The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage
set forth in this text are in accordance with the current recommendations and practice at the time of
publication. However, in view of ongoing research, changes in government regulations, and the con-
stant flow of information relating to drug therapy and drug reactions, the reader is urged to check the
package insert for each drug for any change in indications and dosage and for added warnings and pre-
cautions. This is particularly important when the recommended agent is a new or infrequently em-
ployed drug.
Some drugs and medical devices presented in this publication have Food and Drug Administration
(FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care
provider to ascertain the FDA status of each drug or device planned for use in their clinical practice.
To purchase additional copies of this book, call our customer service department at (800) 638-
3030 or fax orders to (301) 223-2320. International customers should call (301) 223-2300.
Visit Lippincott Williams & Wilkins on the Internet: http://www.lww.com. Lippincott Williams &
Wilkins customer service representatives are available from 8:30 am to 6:00 pm, EST.
