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1. What are the three phases of the vascular permeability, cellular chemotaxis, systemic re-
inflammatory reaction? sponses
2. What happens during vascular inflammatory mediators (histamine or bradykinin) cause
permeability? blood vessels to dilate becoming more permeable allowing
WBC, fluids, platelets to go to site of injury
3. What is followed after the va- enhanced capillary permeability allowing fluid to to flow out
sodilation of arterioles? of the blood vessels to the site of injury
4. What does the increase in fluids dilutes toxins and lowers pH
do?
5. What happens to the inflamed inflamed area becomes red, warm, congested and swollen
area after vascular permeabili- from the vasodilation and fluid
ty?
6. What happens during cellular chemical signal from microbial agents, endothelial cells and
chemotaxis? WBCs attracts platelets and other WBCs to the site of injury
7. What happens to the number increased number of WBCs released from the bone marrow
of WBCs during cellular chemo- into the bloodstream
taxis?
8. What is the third phase of in- Systemic responses
flammatory reaction?
9. What is the first phase of inflam- vascular permeability
matory reaction?
10. what is the second phase of in- cellular chemotaxis
flammatory reaction?
11. What is a titer?
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, NUR 376 - Applied Patho Exam 1: Module 1
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lab test to confirm adequate immune protection vs a partic-
ular antigen by measuring IgM and IgG
12. What CD4+ count do you need <200 cells/mm³
for an AIDS diagnosis?
13. What is the normal range for 800-1200 cells/mm³
CD4 cells?
14. What happens with a CD4 count individuals start to become more susceptible to opportunis-
below 500 cells/mm³? tic infections
15. What is immunocompetence? individuals ability to protect oneself from infectious agents
because of a strong immune system
16. What is immunosuppression? a defective immune system that is placing an individual at
risk for infections
17. What is an opportunistic infec- infection caused by a microorganism that flourishes because
tion? of a hosts deficient immune system
18. What is hospital-acquired infec- infection caused by microorganisms that originated within
tion? the clinical environment
19. What is difficult to treat about they are often caused by antibiotic-resistant bacteria
hospital -acquired infections?
20. What is innate immunity? nonspecific mechanism that defends the body immediately
vs all types of pathogens
21. What are innate defenses? skin, mucus membrane, phagocytic cells, ciliated cells and
mediators of the inflammatory reaction
22. What is acquired immunity?
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