Original Document – Brenner and Stevens’ Pharmacology –
6th Edition – Craig W. Stevens Test Bank
,Brenner and Stevens’ Pharmacology, 6th
Edition
PART A: MULTIPLE CHOICE QUESTIONS
1.
A 42-year-old patient is prescribed acetaminophen for fever. Which of the following correctly
describes the difference between the chemical, generic, and brand names of this drug?
A. Chemical name describes molecular structure, generic name is nonproprietary, brand name is
marketed name.
B. Brand name describes molecular structure, generic name is chemical, chemical name is
marketed.
C. Generic name is molecular structure, brand name is pharmacologic class, chemical name is
marketed.
D. Chemical name and generic name are interchangeable, brand name is only used in research.
Answer: A
Explanation:
• Chemical name: N-acetyl-p-aminophenol, describes molecular structure
• Generic name: Acetaminophen, universally recognized nonproprietary name
• Brand name: Tylenol, the marketed proprietary name
Incorrect options:
• B, C, D misassign the names; chemical name always refers to molecular structure.
2.
Which factor distinguishes a potent drug from a drug with high efficacy?
A. Potency is the dose required to produce a given effect; efficacy is the maximum effect
achievable.
B. Potency is the maximum effect achievable; efficacy is dose required.
C. Both potency and efficacy describe the same concept.
D. Potency only applies to receptor antagonists; efficacy only applies to agonists.
,Answer: A
Explanation:
• Potency reflects how much drug is needed (e.g., EC50)
• Efficacy is the maximal effect regardless of dose
• Incorrect options B–D confuse these terms or limit them incorrectly.
3.
A patient asks why the same drug has multiple brand names. Which explanation is correct?
A. Different pharmaceutical companies market the same generic under different brand names.
B. Each brand name has a different chemical structure.
C. Brand names indicate stronger potency than generic.
D. Brand names are only for over-the-counter drugs.
Answer: A
Explanation:
• Brand names are proprietary marketing terms; chemical structure is the same for all
brands of the same generic.
4.
A clinician wants a drug with a wide therapeutic index. What does this imply?
A. Large margin between effective and toxic dose → safer
B. Drug is highly potent but minimally effective
C. Narrow margin → high safety
D. Drug is ineffective at any dose
Answer: A
Explanation:
• Therapeutic index = TD50 / ED50; higher TI = safer drug
• Incorrect: B–D misinterpret therapeutic index meaning
, 5.
Which of the following is a prototype drug for teaching pharmacology?
A. Morphine for opioids
B. Allopurinol for diabetes
C. Lisinopril for antibiotics
D. Ibuprofen for statins
Answer: A
Explanation:
• Prototype: representative drug for a class, used for teaching and comparison
• Other options assign drugs incorrectly
6.
A patient receives warfarin. The pharmacist explains that the generic is bioequivalent. This
means:
A. Generic has same pharmacokinetics and produces the same clinical effect.
B. Generic has same brand name.
C. Generic always has fewer side effects.
D. Generic has different active ingredients.
Answer: A
Explanation:
• Bioequivalence ensures same absorption, distribution, metabolism, excretion → same
clinical effect
7.
Which naming system is assigned by the United States Adopted Names (USAN) Council?
A. Generic (nonproprietary) names
B. Chemical names
C. Brand names
D. Street names
6th Edition – Craig W. Stevens Test Bank
,Brenner and Stevens’ Pharmacology, 6th
Edition
PART A: MULTIPLE CHOICE QUESTIONS
1.
A 42-year-old patient is prescribed acetaminophen for fever. Which of the following correctly
describes the difference between the chemical, generic, and brand names of this drug?
A. Chemical name describes molecular structure, generic name is nonproprietary, brand name is
marketed name.
B. Brand name describes molecular structure, generic name is chemical, chemical name is
marketed.
C. Generic name is molecular structure, brand name is pharmacologic class, chemical name is
marketed.
D. Chemical name and generic name are interchangeable, brand name is only used in research.
Answer: A
Explanation:
• Chemical name: N-acetyl-p-aminophenol, describes molecular structure
• Generic name: Acetaminophen, universally recognized nonproprietary name
• Brand name: Tylenol, the marketed proprietary name
Incorrect options:
• B, C, D misassign the names; chemical name always refers to molecular structure.
2.
Which factor distinguishes a potent drug from a drug with high efficacy?
A. Potency is the dose required to produce a given effect; efficacy is the maximum effect
achievable.
B. Potency is the maximum effect achievable; efficacy is dose required.
C. Both potency and efficacy describe the same concept.
D. Potency only applies to receptor antagonists; efficacy only applies to agonists.
,Answer: A
Explanation:
• Potency reflects how much drug is needed (e.g., EC50)
• Efficacy is the maximal effect regardless of dose
• Incorrect options B–D confuse these terms or limit them incorrectly.
3.
A patient asks why the same drug has multiple brand names. Which explanation is correct?
A. Different pharmaceutical companies market the same generic under different brand names.
B. Each brand name has a different chemical structure.
C. Brand names indicate stronger potency than generic.
D. Brand names are only for over-the-counter drugs.
Answer: A
Explanation:
• Brand names are proprietary marketing terms; chemical structure is the same for all
brands of the same generic.
4.
A clinician wants a drug with a wide therapeutic index. What does this imply?
A. Large margin between effective and toxic dose → safer
B. Drug is highly potent but minimally effective
C. Narrow margin → high safety
D. Drug is ineffective at any dose
Answer: A
Explanation:
• Therapeutic index = TD50 / ED50; higher TI = safer drug
• Incorrect: B–D misinterpret therapeutic index meaning
, 5.
Which of the following is a prototype drug for teaching pharmacology?
A. Morphine for opioids
B. Allopurinol for diabetes
C. Lisinopril for antibiotics
D. Ibuprofen for statins
Answer: A
Explanation:
• Prototype: representative drug for a class, used for teaching and comparison
• Other options assign drugs incorrectly
6.
A patient receives warfarin. The pharmacist explains that the generic is bioequivalent. This
means:
A. Generic has same pharmacokinetics and produces the same clinical effect.
B. Generic has same brand name.
C. Generic always has fewer side effects.
D. Generic has different active ingredients.
Answer: A
Explanation:
• Bioequivalence ensures same absorption, distribution, metabolism, excretion → same
clinical effect
7.
Which naming system is assigned by the United States Adopted Names (USAN) Council?
A. Generic (nonproprietary) names
B. Chemical names
C. Brand names
D. Street names
