Fitzgerald Pharmacology Midterm Practice ACTUAL UPDATED QUESTIONS
AND CORRECT ANSWERS
C
Terms in this set (200)
A drug's mechanism of action is part of its: Pharmacodynamics
Pharmacokinetics.
Therapeutic transformation.
Pharmacodynamics.
Metabolism.
The process of absorption, distribution, Pharmacokinetics
metabolism and elimination of a drug is
known as:
Therapeutic transformation.
Drug interactions study.
Pharmacokinetics.
Pharmacodynamics.
Which of the following would best Determining the effect of a specific medication dose in treating a disease
describe a pharmacodynamic study?
Determining the half-life of a specific
medication dose
Determining the effect of a specific
medication dose in treating a disease
Determining the Cmax of various
medication doses
Determining the AUC of various medication
doses
,Cmax is best described as: Maximum or peak concentration of a drug observed after its administration.
Percent of dose that enters systemic
circulation after administration of a given
dosage form.
A plotted curve of drug plasma
concentration versus time.
Biotransformation and/or excretion of oral
drug by hepatic mechanisms prior to
entering GI tract.
Maximum or peak concentration of a drug
observed after its administration.
When counseling a 56-year-old woman The oral dose of the medication needed is quite high compared to the injectable for
with type 2 diabetes mellitus, the NP due to issues with GI absorption.
mentions which of the following regarding
the use of semaglutide?
Identical A1C reduction is observed with
the oral or injectable formulation
The oral form should be taken immediately
following the first meal of the day
Tablets can be cut in half if a lower dose is
needed
The oral dose of the medication needed is
quite high compared to the injectable for
due to issues with GI absorption.
Tmax is best defined as: Time to maximum drug level is observed.
Maximum or peak concentration of a drug
observed after its administration.
The drug plasma concentration against
time after a single dose drug
administration.
Time to maximum drug level is observed.
The process of passive diffusion.
7 of 10In the development, testing, and Does the medication appear to have a clinical effect when subjected to a double-
approval of a new medication, which of blind clinical trial?
the following best describes the question
that is being asked in phase 3 testing?
Does the medication appear to have a
clinical effect when subjected to a double-
blind clinical trial?
What is the drug's PK in healthy volunteers?
What are the results of post-marketing
surveillance?
How does the medication work in
laboratory animals?
Age-related changes in the elder include Increase in serum albumin.
all of the following except:
Total body water decreases.
Body weight as fat increases.
Increase in serum albumin.
Decrease in kidney weight.
, When considering the movement of drugs Passive diffusion.
throughout the body, it is important to
consider that the most common form of
drug absorption is via:
Active transport.
Facilitated transfer.
Passive diffusion.
Creation of a pH gradient.
The safety and pharmacokinetics of a new Phase 1
drug are best determined in which phase
of clinical trials?
Pre-clinical
Phase 1
Phase 2
Phase 3
Bioavailability is defined as the: Fraction of the administered drug that reaches systemic circulation.
Solubility of the drug.
Fraction of the administered drug that
reaches systemic circulation.
The drug's alkalinity or acidity.
Protein-bound fraction of a drug.
A nursing mother is taking a medication 8
with a 2-hour half-life and is concerned
about her infant ingesting some of the
drug through breastmilk. The NP knows
that <10% of the original drug dose will
remain in the body after how many hours
following her dose?
2
4
8
12
Drugs that are antagonists exhibit clinical Occupying a receptor site and inhibiting its endogenous activity.
action primarily by:
Stimulating the activity of a receptor site.
Enhancing biotransformation of product.
Forming a therapeutically-active
macromolecule.
Occupying a receptor site and inhibiting its
endogenous activity.
AND CORRECT ANSWERS
C
Terms in this set (200)
A drug's mechanism of action is part of its: Pharmacodynamics
Pharmacokinetics.
Therapeutic transformation.
Pharmacodynamics.
Metabolism.
The process of absorption, distribution, Pharmacokinetics
metabolism and elimination of a drug is
known as:
Therapeutic transformation.
Drug interactions study.
Pharmacokinetics.
Pharmacodynamics.
Which of the following would best Determining the effect of a specific medication dose in treating a disease
describe a pharmacodynamic study?
Determining the half-life of a specific
medication dose
Determining the effect of a specific
medication dose in treating a disease
Determining the Cmax of various
medication doses
Determining the AUC of various medication
doses
,Cmax is best described as: Maximum or peak concentration of a drug observed after its administration.
Percent of dose that enters systemic
circulation after administration of a given
dosage form.
A plotted curve of drug plasma
concentration versus time.
Biotransformation and/or excretion of oral
drug by hepatic mechanisms prior to
entering GI tract.
Maximum or peak concentration of a drug
observed after its administration.
When counseling a 56-year-old woman The oral dose of the medication needed is quite high compared to the injectable for
with type 2 diabetes mellitus, the NP due to issues with GI absorption.
mentions which of the following regarding
the use of semaglutide?
Identical A1C reduction is observed with
the oral or injectable formulation
The oral form should be taken immediately
following the first meal of the day
Tablets can be cut in half if a lower dose is
needed
The oral dose of the medication needed is
quite high compared to the injectable for
due to issues with GI absorption.
Tmax is best defined as: Time to maximum drug level is observed.
Maximum or peak concentration of a drug
observed after its administration.
The drug plasma concentration against
time after a single dose drug
administration.
Time to maximum drug level is observed.
The process of passive diffusion.
7 of 10In the development, testing, and Does the medication appear to have a clinical effect when subjected to a double-
approval of a new medication, which of blind clinical trial?
the following best describes the question
that is being asked in phase 3 testing?
Does the medication appear to have a
clinical effect when subjected to a double-
blind clinical trial?
What is the drug's PK in healthy volunteers?
What are the results of post-marketing
surveillance?
How does the medication work in
laboratory animals?
Age-related changes in the elder include Increase in serum albumin.
all of the following except:
Total body water decreases.
Body weight as fat increases.
Increase in serum albumin.
Decrease in kidney weight.
, When considering the movement of drugs Passive diffusion.
throughout the body, it is important to
consider that the most common form of
drug absorption is via:
Active transport.
Facilitated transfer.
Passive diffusion.
Creation of a pH gradient.
The safety and pharmacokinetics of a new Phase 1
drug are best determined in which phase
of clinical trials?
Pre-clinical
Phase 1
Phase 2
Phase 3
Bioavailability is defined as the: Fraction of the administered drug that reaches systemic circulation.
Solubility of the drug.
Fraction of the administered drug that
reaches systemic circulation.
The drug's alkalinity or acidity.
Protein-bound fraction of a drug.
A nursing mother is taking a medication 8
with a 2-hour half-life and is concerned
about her infant ingesting some of the
drug through breastmilk. The NP knows
that <10% of the original drug dose will
remain in the body after how many hours
following her dose?
2
4
8
12
Drugs that are antagonists exhibit clinical Occupying a receptor site and inhibiting its endogenous activity.
action primarily by:
Stimulating the activity of a receptor site.
Enhancing biotransformation of product.
Forming a therapeutically-active
macromolecule.
Occupying a receptor site and inhibiting its
endogenous activity.
