Abrams Clinical Drug Therapy 12th Edition Frandsen Test Bank 2025 I Rationales

ABRAM’SkCLINICALkDRUGkTHERAPYkRATIONALESkFOR
NURSINGkPRACTICEk13thkEDITIONkGERALYNkFRANDSEN’SkTESTBANK/COM
PLETEkGUIDEk2024-2025/ALLkCHAPTERSk1-61

,Chapterk1:kThekFoundationkofkPharmacology:kQualitykandkSafety
1. Akpatientkdiagnosedkwithkobsessive–
compulsivekdisorderkhaskbeenkprescribedkoralkparoxetinekhydrochloride.kWhatk iskt
hekexpectedkeffectkforkthiskprescription?
A. Curativekeffectkonksymptoms
B. Systemickeffectkonksymptoms
C. Localkeffectkonksymptoms
D. Parenteralkeffectkonksymptoms
ACCURATEkANSWER:-B
REASONING:-
>>>Pharmaceuticalkdrugkthatkproduceksystemickeffectskarektakenkintokthekbody,kcirculatedkt
hroughkthekbloodstreamktoktheirksiteskofkactionkinkvariouskbodyktissues,kandkeventuallykelimin
atedkfromkthekbody.kCurativekagentskarekgivenktokcurekakdiseasekprocess.kInkthiskcase,kparox
etinekhydrochloridekwillkcontrolktheksymptomskbutknotkcurekthekdisorder.
Pharmaceuticalkdrugkwithklocalkeffects,ksuchkasksunscreenkandklocalkanesthetics,kactkmainlykat
ktheksitekofkapplication.kParoxetinekhydrochloridekisknotkadministeredkparenterally.kParenter
alkagentskarekadministeredksubcutaneously,kintramuscularly,korkintravenously.

POINTS: 1 REFERENCE: p.k3,kIntroduction OBJ: 1
NAT:kHospitalkclientkNeeds:kPhysiologicalkIntegrity:kPharmacologicalkandkParenteralkThe
rapieskTOP: Chapter:k1:kThekFoundationkofkPharmacology:kQualitykandkSafety
KEY:k IntegratedkProcess:kNursingkProcess
BLM:k CognitivekLevel:kUnderstand NOT:k MultiplekChoice

2. Akhospitalkclientkhaskbeenkprescribedkankantibiotic.kThiskpharmaceuticalkdrugkiskakn
aturallykoccurringksubstancekthatkhaskbeenkcheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOtkkMikskkanotherkna
.C
mekforkthisktypekofkpharmaceuticalkdrug?
A. Synthetickdrug
B. Semisynthetickdrug
C. Biotechnologykdrug
D. Prototypekdrug
ACCURATEkANSWER:-B
REASONING:-
>>>Semisynthetickpharmaceuticalkdrugk(e.g.,kmanykantibiotics)kareknaturallykoccurringksub
stanceskthatkhavekbeenkchemicallykmodified.kSynthetickpharmaceuticalkdrugkarekmorekstan
dardizedkinktheirkchemicalkcharacteristics,kmorekconsistentkinktheirkeffects,kandklessklikelyktok
producekallergickreactions.kBiotechnologykpharmaceuticalkdrugkinvolvekmanipulatingkDNAka
ndkRNAkandkrecombiningkgeneskintokhybridkmoleculeskthatkcankbekinsertedkintoklivingkorga
nisms.kPrototypekpharmaceuticalkdrugkarekthekfirstkdrugkofkakparticularkgroupktokbekdevelo
ped.

POINTS: 1 REFERENCE: p.k3,kDrugkSources OBJ: 1
NAT:kHospitalkclientkNeeds:kPhysiologicalkIntegrity:kPharmacologicalkandkParenteralkThe
rapieskTOP: Chapter:k1:kThekFoundationkofkPharmacology:kQualitykandkSafety
KEY:k IntegratedkProcess:kNursingkProcess
BLM:k CognitivekLevel:kUnderstand NOT:k MultiplekChoice

3. Whichkclassificationkappliesktokmorphine?
A. Centralknervousksystemkdepressant
B. Centralknervousksystemkstimulant

, C. Anti-inflammatory
D. Antihypertensive
ACCURATEkANSWER:-A
REASONING:-
>>>Pharmaceuticalkdrugkarekclassifiedkaccordingktoktheirkeffectskonkparticularkbodyksystem
s,ktheirktherapeutickuses,kandktheirkchemicalkcharacteristics.kMorphinekiskclassifiedkaskakcentral
knervousksystemkdepressantkandkwillkproducekthiskeffectkinkthekhospitalkclient.kAkcentralknervou
sksystemkstimulantkincreaseskattentionkandkraiseskmood.kAnkanti-
inflammatorykagentkdecreaseskinflammationkatktheksitekofktissuekorkjointkinflammation.kAnkanti
hypertensivekagentkreduceskbloodkpressure.

POINTS: 1 REFERENCE:
p.k3,kDrugkClassificationskandkPrototypeskOBJ: 1
NAT:kHospitalkclientkNeeds:kPhysiologicalkIntegrity:kPharmacologicalkandkParenteralkThe
rapieskTOP: Chapter:k1:kThekFoundationkofkPharmacology:kQualitykandkSafety
KEY:k IntegratedkProcess:kNursingkProcess
BLM:k CognitivekLevel:kRemember NOT:k MultiplekChoice

4. Akhospitalkclientkiskadministeredkamoxicillin.kThekgenericknamekofkthiskpharmaceuticalkdrugkb
elongsktokwhichkdrugkgroup?
A. Selectivekserotoninkreuptakekinhibitors
B. Diuretics
C. Penicillins
D. ACEkinhibitors
ACCURATEkANSWER:-C
REASONING:->>>Thekgenericknamekoftenkindicateskthekdrugkgroupk(e.g.,kpharmaceuticalkdrug
GRADESBOOST.CO
withkgenericknameskendingkink“cillin”karekpenicillins).kSelectivekserotoninkreuptakekinhibit
orskarekpharmaceuticalkdrugs
thatkhavekantidepressantkeffects;kSSRIkiskakbroadkclassification,knotkakgenerickname.kDiureticsk
arekpharmaceuticalkdrugskthatkincreasekurinekoutput;kdiuretickiskakbroadkclassification,knotkak
generickname.kACEkinhibitorkiskthekbroadkclassificationkforkthekangiotensinkreceptorkblockers,k
notkthekgenerickname.

POINTS: 1 REFERENCE: p.k3,kDrugkNames OBJ: 2
NAT:kHospitalkclientkNeeds:kPhysiologicalkIntegrity:kPharmacologicalkandkParenteralkThe
rapieskTOP: Chapter:k1:kThekFoundationkofkPharmacology:kQualitykandkSafety
KEY:k IntegratedkProcess:kNursingkProcess
BLM:k CognitivekLevel:kUnderstand NOT:k MultiplekChoice

5. ThekadministrationkofkdiphenhydraminekiskregulatedkbykwhichkU.S.kgovernmentkagency?
A. PublickHealthkService
B. FederalkTradekCommission
C. OccupationalkSafetykandkHealthkAdministration
D. FoodkandkDrug
kAdministration


ACCURATEkANSWER:-D

, REASONING:-
>>>ThekFoodkandkDrugkAdministrationkapproveskpharmaceuticalkdrugkforkover-kthe-
counterkavailability,kincludingkthektransferkofkpharmaceuticalkdrugkfromkprescriptionktokOTC
kstatus,kandkmaykrequirekclinicalktrialsktokdeterminektheksafetykandkeffectivenesskofkOTCkuse
.kThekPublickHealthkServicekiskregulatedkbykthekstatektokmaintainkthekhealthkofkindividualkciti
zenskofkthekstate.kThekFederalkTradekCommissionkregulateskimportskandkexportskthroughoutk
theknation.kThekOccupationalkSafetykandkHealthkAdministrationkregulatesksafetykwithinkthekw
orkplace.

POINTS: 1 REFERENCE: p.k4,kPrescriptionkandkNonprescription
PharmaceuticalkdrugkOBJ: 4
NAT:kHospitalkclientkNeeds:kPhysiologicalkIntegrity:kPharmacologicalkandkParenteralkThe
rapieskTOP: Chapter:k1:kThekFoundationkofkPharmacology:kQualitykandkSafety
KEY:k IntegratedkProcess:kNursingkProcess
BLM:k CognitivekLevel:kUnderstand NOT:k MultiplekChoice

6. InkthekU.S.,kthekadministrationkofkanabolicksteroidskiskregulatedkbykwhichklaw?
A. ThekFood,kDrug,kandkCosmetickActkofk1938
B. ThekComprehensivekDrugkAbusekPreventionkandkControlkAct
C. ThekHarrisonkNarcotickAct
D. ThekSherleykAmendment
ACCURATEkANSWER:-B
REASONING:-
>>>ThekComprehensivekDrugkAbusekPreventionkandkControlkActkregulateskthekmanufacturek
andkdistributionkofknarcotics,kstimulants,kdepressants,khallucinogens,kandkanabolicksteroids.kTh
ekFood,kDrug,kandkCosmetickActkofk1938krevisedkandkbroadenedkFDAkpowerskandkresponsi
bilities,kgivingkthekFDAkcontrolkoverkdrugksafety.kThekHarrisonkNarcotickActkrestrictedkthekimp
ortation,kmanufacture,ksale,kandkusekofkopium,kcocaine,kmarijuana,kandkotherkpharmaceuticalkdru
gkthatkthekactkdkekfki GnkeRd AaDsk E
naSrcBoO
tiO
csS
.kTh.eCSOhM
erleykAmendmentkofk1912kprohibitedkfraudulen
tkclaimskofkdrugkeffectiveness.

POINTS: 1 REFERENCE: p.k4,kPrescriptionkandkNonprescription
PharmaceuticalkdrugkOBJ: 3
NAT:kHospitalkclientkNeeds:kPhysiologicalkIntegrity:kPharmacologicalkandkParenteralkThe
rapieskTOP: Chapter:k1:kThekFoundationkofkPharmacology:kQualitykandkSafety
KEY:k IntegratedkProcess:kNursingkProcess
BLM:k CognitivekLevel:kRemember NOT:k MultiplekChoice

7. Aknursingkattendantkiskresponsiblekforkmaintainingkankaccuratekcountkandkrecordkofkthek
controlledksubstanceskonktheknursingkdivision.kThisknursingkactionkiskregulatedkbykwhich
U.S.klawkorkagency?
A. ThekFood,kDrug,kandkCosmetickActkofk1938
B. ThekPublickHealthkService
C. ThekDrugkEnforcementk Administration
D. ThekSherleykAmendmentk
ACCURATEkANSWER:-C